Serum adiponectin and metabolic profile in women with polycystic ovarian syndrome in relation to body mass index

Background: Polycystic ovarian syndrome is a common endocrine disorder which affects approximately 5-10% of women in reproductive age. It is both a reproductive endocrinopathy and a metabolic disorder.Methods: 160 women aged 18 to 40 years attending obstetrics and gynaecology clinic at Federal medical centre, Owerri, Imo State Nigeria were recruited and divided into 2 groups (women diagnosed with PCOS using Rotterdam criteria and control) of 80 participants each. Anthropometric data were collected, and participants categorized into 3 based on BMI. Fasting blood samples was collected for biochemical analyses. Data were analyzed using the Statistical Package for Social Sciences SPSS version 23.0, and level of significance set at p<0.05.Results: The mean serum levels of adiponectin and high density lipoprotein (HDL-C) were significantly lower while fasting plasma glucose, serum insulin, homeostatic model assessment for insulin resistance, total cholesterol, low density lipoprotein (LDL-C), very low density lipoprotein (VLDL-C) and triglyceride were significantly higher in women with PCOS when compared with the control (p<0.05) as well as in obese when compared with normal weight women with PCOS (p<0.05). BMI negatively correlated with serum adiponectin and HDL-C, but positively correlated with FPG, insulin, HOMA-IR, TC, TG, LDL-C and VLDL-C in women with PCOS (p<0.05).Conclusions: This study highlights the prevalent biochemical and metabolic derangements in PCOS patients and was more evident in the obese and overweight patients. Early detection with subsequent application of preemptive measures including lifestyle modifications are therefore essential in the management of PCOS patients

Effects of Climate Change on Fluted Pumpkin Production and Adaptaton Measures Used Among Farmers in Rivers State

The importance of fluted pumpkin crop in rural household economy cannot be over emphasized. Farmers in the South South Nigeria depend greatly on fluted pumpkin for its many uses. The production however is beset with a myriad of constraints of which climate change is one of the most outstanding. The study assessed the effects of climate change and adaptation measures used by fluted pumpkin farmers in Ikwerre Local Government Area(LGA) of Rivers State, Southsouth Nigeria. Multi-stage sampling technique was used to select respondents for the study. Out of the twelve communities that make up Ikwerre LGA, six communities were randomly chosen from which one hundred and eighty fluted pumpkin farmers were proportionately selected. Interview schedule and focus group discussion were used to elicit in depth information from respondents. Data were analyzed using percentage, frequency count and mean. Tables and charts were used in presentation of data. The result of the study showed that 51 percent of the respondents were female, majority were married (77 percent) and were full time farmers (79 percent). Relatively large proportion had no formal education (42 percent) and indicated both consumption and sale (79 percent) as the major aim of production. The respondents perceived that unpredictable climate condition, changes in rainfall pattern, changes in rainfall distribution, reduced yield of fluted pumpkin and reduction of family income were the major effects of climate change on fluted pumpkin production. A combination of fluted pumpkin production with other income generating activities was shown to be the most widely used adaptation strategy by respondents. Based on the results of the study it was recommended that improved extension services that can provide the needed farming inputs (fluted pumpkin seedlings, fertilizers e.t.c) as well as useful and relevant information on climate change and adaptation strategies should be made available to the people

Effects of Climate Change on Fluted Pumpkin Production and Adaptaton Measures Used Among Farmers in Rivers State

The importance of fluted pumpkin crop in rural household economy cannot be over emphasized. Farmers in the South South Nigeria depend greatly on fluted pumpkin for its many uses. The production however is beset with a myriad of constraints of which climate change is one of the most outstanding. The study assessed the effects of climate change and adaptation measures used by fluted pumpkin farmers in Ikwerre Local Government Area(LGA) of Rivers State, Southsouth Nigeria. Multi-stage sampling technique was used to select respondents for the study. Out of the twelve communities that make up Ikwerre LGA, six communities were randomly chosen from which one hundred and eighty fluted pumpkin farmers were proportionately selected. Interview schedule and focus group discussion were used to elicit in depth information from respondents. Data were analyzed using percentage, frequency count and mean. Tables and charts were used in presentation of data. The result of the study showed that 51 percent of the respondents were female, majority were married (77 percent) and were full time farmers (79 percent). Relatively large proportion had no formal education (42 percent) and indicated both consumption and sale (79 percent) as the major aim of production. The respondents perceived that unpredictable climate condition, changes in rainfall pattern, changes in rainfall distribution, reduced yield of fluted pumpkin and reduction of family income were the major effects of climate change on fluted pumpkin production. A combination of fluted pumpkin production with other income generating activities was shown to be the most widely used adaptation strategy by respondents. Based on the results of the study it was recommended that improved extension services that can provide the needed farming inputs (fluted pumpkin seedlings, fertilizers e.t.c) as well as useful and relevant information on climate change and adaptation strategies should be made available to the people

Trends and Perspective of Metabolic Syndrome

Overweight, sedentary lifestyles, and some degree of insulin resistance are only a few of the traits linked with individuals who have the metabolic syndrome. Additional risk factors include a sedentary or inactive lifestyle, the use of psychiatric drugs, and excessive alcohol use. Weight gain and insulin resistance are connected with the metabolic syndrome. The most effective methods of losing weight are low-calorie diets and increased physical activity. Preliminary research indicates that individuals who consume a paleolithic diet may reduce three of the five quantitative risk factors for cardiovascular disease