Approach to Diagnosis of Salivary Gland Disease from Nuclear Medicine Images

Nuclear medicine images can help in the diagnosis and assessment of some salivary disorders. 99mTcO4−, gallium-67-citrate scintigraphy will be an indication of the function of salivary gland together and it will be used for the diffuse diseases such as sialadenitis, Sjögren’s syndrome, sarcoidosis, glossopharyngeal paralysis, and irradiation. It is also effective for distinguishing benign tumor legion with Warthin’s tumor and others. Moreover, fluorodeoxyglucose positron emission tomography (FDG-PET) is an indispensable modality for determining the localization, focal lesions, and staging of many malignant tumors, the fluorodeoxyglucose (FDG) accumulation is visually and semi-quantitatively assessed using the standardized uptake value (SUV), which is the ratio of uptake to the injected dose per unit body weight. Also for radioactive iodine therapy, attention should be paid to adverse reactions. It is important to note that acute/chronic salivary gland disorders are associated with radioiodine therapy for the treatment of postoperative thyroid cancer. Coordination among healthcare providers including nurses, radiological technologists, and doctors of all departments involved in treatment is important for achieving effective outcomes

Distributions of biogeochemical parameters in the pool and interstitial waters in sand bar system of the Kizu River

Distributions of biogeochemical parameters in temporary pools (TAMARI), riparian side arm of river (WANDO) and interstitial waters were investigated in the sand bars along the lower reaches of the Kizu River. Dissloved inorganic nitrogen (DIN) and phosphate (DIP) concentrations in TAMARI and WANDO waters varied greatly compared with those in river waters. Low concentrations of DIN and DIP were often observed simultaneously in TAMARI waters. The DIN concentrations of most intersitial waters were similar or high in comparison to those of river waters. Low concentrations of DIN and DIP were often observed separately in intersitial waters. Concentrations of biogeochemical constituents clearly varied greatly in the waters of sand bar systems, and the relationships between each biogeochemical constituents were different between surface water (TAMARI and WANDO) and subsurface (intersitial) waters of the Kizu River.Article信州大学山地水環境教育研究センター研究報告 2: 63-67(2004)departmental bulletin pape

Development of Simple Sequence Repeat (SSR) Markers and Their Use to Assess Genetic Diversity in Apomictic Guineagrass (\u3cem\u3ePanicum Maximum\u3c/em\u3e Jacq.)

Guineagrass is an important and widely grown tropical forage grass. Despite its importance and increasing popularity, only little is known about its genetic diversity (Ebina et al., 2001). Such information is useful for the selection of diverse parents in breeding programmes. Moreover, no simple sequence repeat (SSR) markers have been reported in any apomixis species. In this study SSR markers were developed and used to investigate genetic diversity in germplasm of apomictic guineagrass

A new heterozygous compound mutation in the CTSA gene in galactosialidosis

Galactosialidosis is an autosomal recessive lysosomal storage disease caused by the combined deficiency of lysosomal β-galactosidase and neuraminidase due to a defect in the protective protein/cathepsin A. Patients present with various clinical manifestations and are classified into three types according to the age of onset: the early infantile type, the late infantile type, and the juvenile/adult type. We report a Japanese female case of juvenile/adult type galactosialidosis. Clinically, she presented with short stature, coarse facies, angiokeratoma, remarkable action myoclonus, and cerebellar ataxia. The patient was diagnosed with galactosialidosis with confirmation of impaired β-galactosidase and neuraminidase function in cultured skin fibroblasts. Sanger sequencing for CTSA identified a compound heterozygous mutation consisting of NM_00308.3(CTSA):c.746 + 3A>G and c.655-1G>A. Additional analysis of her mother’s DNA sequence indicated that the former mutation originated from her mother, and therefore the latter was estimated to be from the father or was a de novo mutation. Both mutations are considered pathogenic owing to possible splicing abnormalities. One of them (c.655-1G>A) is novel because it has never been reported previously

Discovery of a new dwarf nova, TSS J022216.4+412259.9: WZ Sge-type dwarf novae breaking the shortest superhump period record

We report on the time-resolved CCD photometry of a newly discovered variable star, TSS J022216.4+412259.9 during the outburst in 2005 November-December brightening. The obtained light curves unambiguously showed 0.2-0.3 mag modulations, which we confirmed to be the superhump observed among SU UMa-type dwarf novae. We also performed a period search for the data obtained during the outburst plateau phase, and revealed the existence of the two periodicities: 0.054868(98) days for the first two nights and 0.055544(26) days for the following plateau phase. This bi-periodicity is hardly observed in usual SU UMa-type dwarf novae, but characteristic of WZ Sge-type stars. We undoubtedly detected a rebrightening in the post-outburst stage, which is typical of short-period SU UMa-type dwarf novae including WZ Sge-type stars. These observations suggests that TSS J022216.4+412259.9 may be a new WZ Sge stars breaking the shortest superhump period of 0.05648 days for V592 Her among this class with a known superhump period so far.Comment: 5 pages, 6 figures, accepted for PASJ lette