Observing Water Vapour in the Planetary Boundary Layer from the Short-Wave Infrared

Water vapour is a key greenhouse gas in the Earth climate system. In this golden age of satellite remote sensing, global observations of water vapour fields are made from numerous instruments measuring in the ultraviolet/visible, through the infrared bands, to the microwave regions of the electromagnetic spectrum. While these observations provide a wealth of information on columnar, free-tropospheric and upper troposphere/lower stratosphere water vapour amounts, there is still an observational gap regarding resolved bulk planetary boundary layer (PBL) concentrations. In this study we demonstrate the ability of the Greenhouse Gases Observing SATellite (GOSAT) to bridge this gap from highly resolved measurements in the shortwave infrared (SWIR). These new measurements of near surface columnar water vapour are free of topographic artefacts and are interpreted as a proxy for bulk PBL water vapour. Validation (over land surfaces only) of this new data set against global radiosondes show low biases that vary seasonally between −2% to 5%. Analysis on broad latitudinal bands show biases between −3% and 2% moving from high latitudes to the equatorial regions. Finally, with the extension of the GOSAT program out to at least 2027, we discuss the potential for a new GOSAT PBL water vapour Climate Data Record (CDR)

Evaluation of tropospheric water vapour and temperature profiles retrieved from MetOp-A by the Infrared and Microwave Sounding scheme

Since 2007, the Meteorological Operational satellite (MetOp) series of platforms operated by the European Organisation for the Exploitation of Meteorological Satellites (EUMETSAT) has provided valuable observations of the Earth's surface and atmosphere for meteorological and climate applications. With 15 years of data already collected, the next generation of MetOp satellites will see this measurement record extend to and beyond 2045. Although a primary role is in operational meteorology, tropospheric temperature and water vapour profiles will be key data products produced using infrared and microwave sounding instruments on board. Considering the MetOp data record that will span 40 years, these profiles will form an essential climate data record (CDR) for studying long-Term atmospheric changes. Therefore, the performance of these products must be characterized to support the robustness of any current or future analysis. In this study, we validate 9.5 years of profile data produced using the Infrared and Microwave Sounding (IMS) scheme with the European Space Agency (ESA) Water Vapour Climate Change Initiative (WV_cci) project against radiosondes from two different archives. The Global Climate Observing System (GCOS) Reference Upper-Air Network (GRUAN) and Analyzed RadioSoundings Archive (ARSA) data records were chosen for the validation exercise to provide the contrast between global observations (ARSA) with sparser characterized climate measurements (GRUAN). Results from this study show that IMS temperature and water vapour profile biases are within 0.5ĝ€¯K and 10ĝ€¯% of the reference for "global"scales. We further demonstrate the difference between diurnal sampling and cloud amount match-ups on observed biases and discuss the implications that sampling also plays on attributing these effects. Finally, we present the first look at the profile bias stability from the IMS product, where we observe global stabilities ranging from-0.32ĝ€¯±ĝ€¯0.18 to 0.1ĝ€¯±ĝ€¯0.27ĝ€¯K per decade and-1.76ĝ€¯±ĝ€¯0.19 to 0.79ĝ€¯±ĝ€¯0.83ĝ€¯%ĝ€¯ppmv (parts per million by volume) per decade for temperature and water vapour profiles, respectively. We further break down the profile stability into diurnal and latitudinal values and relate all observed results to required climate performance. Overall, we find the results from this study demonstrate the real potential for tropospheric water vapour and temperature profile CDRs from the MetOp series of platforms.</p

Longitudinal immune profiling reveals key myeloid signatures associated with COVID-19

COVID-19 pathogenesis is associated with an exaggerated immune response. However, the specific cellular mediators and inflammatory components driving diverse clinical disease outcomes remain poorly understood. We undertook longitudinal immune profiling on both whole blood and peripheral blood mononuclear cells of hospitalized patients during the peak of the COVID-19 pandemic in the United Kingdom. Here, we report key immune signatures present shortly after hospital admission that were associated with the severity of COVID-19. Immune signatures were related to shifts in neutrophil to T cell ratio, elevated serum IL-6, MCP-1, and IP-10 and modulation of CD14+ monocyte phenotype and function. Modified features of CD14+ monocytes included poor induction of the prostaglandin-producing enzyme, COX-2, and enhanced expression of the cell cycle marker Ki-67. Longitudinal analysis revealed reversion of some immune features back to the healthy median level in patients with a good eventual outcome. These findings identify previously unappreciated alterations in the innate immune compartment of patients with COVID-19 and lend support to the idea that therapeutic strategies targeting release of myeloid cells from bone marrow should be considered in this disease. Moreover, they demonstrate that features of an exaggerated immune response are present early after hospital admission, suggesting that immunomodulating therapies would be most beneficial at early time points