THE EFFECT OF HYPOXIC BRAIN DAMAGE ON THE SURVIVAL OF PREMATURE INFANTS

The central nervous system injuries are a common neonatal pathology, hypoxia being one of the main causes of cerebral dysfunction. The purpose of this study was studying the incidence of hypoxic cerebral disorders in premature infants with an extremely low body weight and a very low birth weight and revealing the risk factors that adversely affected the disease outcome. The subject of the study was preterm infants whose gestational age did not exceed 31 weeks. The main criterion for inclusion into the study was the presence of hypoxic-ischemic and hypoxic-hemorrhagic brain damage. To reveal the perinatal risk factors, the somatic health of mothers, and pregnancy and childbirth peculiarities were studied. The structure of children’s pathology and intensive care techniques were analyzed. Cerebral disorders were verified in 42 out of 176 patients (23.5 %). 2–3rd-degree intraventricular hemorrhage was diagnosed in 34 newborns (80.9 %), severe ischemia in 8 children (19.1 %). To determine the structure of the disease outcome, all children were divided into deceased and survivors. A fatal outcome was observed in 14 cases (33.3 %). The mothers of deceased children were more likely to have obstetric and concomitant extragenital pathologies. Analysis of pediatric pathology showed that the hemodynamically significant functioning arterial duct and severe asphyxia in childbirth were much more frequent in deceased children. Intensive therapy of deceased children included «hard» parameters of artificial ventilation and high doses of cardiotonic drugs. Thus the presented risk factors can be considered as predictors of an unfavorable outcome in children with this pathology

ФОРМУВАННЯ ПОЗИТИВНИХ ЗМІН У РОБОТІ ВИКЛАДАЧІВ АКАДЕМІЇ НА ПІДСТАВІ АНКЕТУВАННЯ

In the article attention is paid to an opportunity to reveal problems of teachers according to questioning data and formation of positive changes in improvement of teachers` work.У статті звернено увагу на можливість за даними анкетування викладачів виявляти проблеми викладачів і формувати позитивні зміни в поліпшенні їх роботи

ВНУТРИГОСПИТАЛЬНАЯ ТРАНСПОРТИРОВКА ПАЦИЕНТОВ С РАЗРЫВОМ АРТЕРИАЛЬНЫХ АНЕВРИЗМ ГОЛОВНОГО МОЗГА

Goal: to evaluate cerebral hemodynamics in the patients with aneurysm rupture during their transportation within the hospital. Materials and methods. 60 patients divided into 2 groups were included into the study. Patients from group 1 were transported as it was traditionally adopted in the clinic; additional sedation and continuous administration of nimodipine were used in group 2. Results. The increase of medium blood velocity in cerebral vessels by 23.5% on the operated side was observed in group 1. Continuous administration nimodipine solution during all transport stages allows reducing the velocity increase in cerebral vessels on the operated side down to 4.5%. Conclusion. The increase of cerebral angiospasm was observed during intrahospital transportation. The need for additional sedation has been justified for the patients transported while being on the artificial pulmonary ventilation. Цель: оценить церебральную гемодинамику у пациентов с разрывом аневризм при внутрибольничной транспортировке. Материалы и методы. Проведено исследование у 60 пациентов, разделенных на две группы. Больные 1-й группы транспортированы по принятой в клинике методике, а 2-й − с применением дополнительной седации и непрерывным введением нимодипина. Результаты. Отмечено нарастание средних скоростей по церебральным сосудам на 23,5% на стороне оперативного вмешательства в 1-й группе. Применение непрерывного введения раствора нимодипина на всех этапах транспортировки позволяет снизить повышение скорости по церебральным сосудам на стороне хирургического вмешательства до 4,5%. Заключение. Выявлено повышение показателей церебрального ангиоспазма при внутригоспитальной транспортировке. Обоснована необходимость применения дополнительной седации у пациентов, транспортируемых с применением искусственной вентиляции легких.

INTRAHOSPITAL TRANSPORT OF PATIENTS WITH RUPTURE OF CEREBRAL ARTERY ANEURYSM

Goal: to evaluate cerebral hemodynamics in the patients with aneurysm rupture during their transportation within the hospital. Materials and methods. 60 patients divided into 2 groups were included into the study. Patients from group 1 were transported as it was traditionally adopted in the clinic; additional sedation and continuous administration of nimodipine were used in group 2. Results. The increase of medium blood velocity in cerebral vessels by 23.5% on the operated side was observed in group 1. Continuous administration nimodipine solution during all transport stages allows reducing the velocity increase in cerebral vessels on the operated side down to 4.5%. Conclusion. The increase of cerebral angiospasm was observed during intrahospital transportation. The need for additional sedation has been justified for the patients transported while being on the artificial pulmonary ventilation

Coexistence of magnetic states and metamagnetism in the Bi

The dichalcogenide Bi2Te3 and Bi2Se3 crystals belong to the 3D topological insulator family. Doping the crystals with magnetic ions can break the time-reversal symmetry and open an energy gap at surface Dirac points. This provides the opportunity of manipulating the surface transport and observing the anomalous quantum Hall effect. We studied magnetic properties of three single-crystalline Bi$_{2-x}$ CrxSe3 samples with $x = 0.01$ , 0.03, and 0.06 within a temperature range from 2 to 300 K. The dc magnetization revealed the coexistence of antiferromagnetic and ferromagnetic ordering and paramagnetism. Their significance depends on the chromium content. The ferromagnetic phase transition was suppressed by high enough magnetic field. The antiferromagnetic transition near 80 K did not shift visibly up to 50 kOe. The Curie-Weiss law approximation gave the effective magnetic moment $\mu_{\textit{eff}}$ close to $4.9\;{\mu_{B}}$ , which corresponds to divalent chromium ions. Metamagnetic phenomena were found for crystals with $x=0.03$ and 0.06

Magnetic Studies of Iron-Doped Probable Weyl Semimetal WTe2

The non-trivial topology of electronic bands in Weyl semimetals originates from band inversion due to strong spin–orbit coupling. The Weyl semimetals have pairs of Weyl gap-less nodes in the bulk Brillouin zone. The tungsten ditelluride WTe2 likely belongs to type II Weyl semimetals. Doping WTe2 with magnetic ions could induce magnetic ordering in this crystal, which provides prospects for practical applications. We studied the magnetic properties of the iron-doped single crystals Fe0.03W0.97Te2, annealed and unannealed, in comparison with the undoped WTe2. Measurements of the dc magnetization were carried out from 1.8 to 400 K. We revealed pronounced ferromagnetic ordering that was affected by annealing. Anomalies associated with antiferromagnetism and paramagnetism were also found. The magnetic order was suppressed by a field of 60 kOe. The rise in susceptibility with increasing temperature was observed at high temperatures in all samples and was treated using a model developed for Weyl semimetals. The Curie–Weiss law fit at 60 kOe showed that the effective magnetic moment was close to that of Fe2+. Metamagnetism was demonstrated for the unannealed doped WTe2 crystal. The data for the heat capacity of the iron-doped sample agreed with results for the undoped WTe2