6 research outputs found

    ΠŸΠ°Ρ€Π°Π²Π΅Ρ€Ρ‚Π΅Π±Ρ€Π°Π»ΡŒΠ½Π°Ρ Π±Π»ΠΎΠΊΠ°Π΄Π° ΠΏΡ€ΠΈ Π»Π΅Ρ‡Π΅Π½ΠΈΠΈ ΠΏΠ°Ρ†ΠΈΠ΅Π½Ρ‚ΠΎΠ² с Π·Π°ΠΊΡ€Ρ‹Ρ‚ΠΎΠΉ Ρ‚Ρ€Π°Π²ΠΌΠΎΠΉ Π³Ρ€ΡƒΠ΄ΠΈ

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    The study was conducted in the Thoracoabdominal Department of the N.V. Sklifosovsky Research Institute for Emergency Medicine to explore the role of paravertebral block in the treatment of blunt chest trauma. The study included 715 patients with isolated chest trauma hospitalized between January 1, 2020 and August 2021. 55 patients received analgesic therapy in the form of paravertebral block. The comparison group included 660 patients who did not undergo paravertebral block, in their case pain relief was provided by systemic administration of analgesics. The compared groups did not differ significantly in sex and age composition. There were also no differences in the frequency of chronic diseases and interpleural complications. There were no significant complications during the block. The comparison revealed a significant decrease in the incidence of pleurisy and a shorter length of stay in hospital. Paravertebral block is an effective and safe method of pain management for patients with blunt chest trauma. The use of this technique reduces the incidence of post-traumatic pleurisy and duration of hospitalization.ИсслСдованиС ΠΏΡ€ΠΎΠ²Π΅Π΄Π΅Π½ΠΎ Π² Ρ‚ΠΎΡ€Π°ΠΊΠΎΠ°Π±Π΄ΠΎΠΌΠΈΠ½Π°Π»ΡŒΠ½ΠΎΠΌ ΠΎΡ‚Π΄Π΅Π»Π΅Π½ΠΈΠΈ НИИ БП ΠΈΠΌ. Н.Π’. Бклифосовского с Ρ†Π΅Π»ΡŒΡŽ изучСния значСния ΠΏΠ°Ρ€Π°Π²Π΅Ρ€Ρ‚Π΅Π±Ρ€Π°Π»ΡŒΠ½ΠΎΠΉ Π±Π»ΠΎΠΊΠ°Π΄Ρ‹. Π‘Ρ‹Π»ΠΎ Π²ΠΊΠ»ΡŽΡ‡Π΅Π½ΠΎ 715 ΠΏΠ°Ρ†ΠΈΠ΅Π½Ρ‚ΠΎΠ² с ΠΈΠ·ΠΎΠ»ΠΈΡ€ΠΎΠ²Π°Π½Π½ΠΎΠΉ Ρ‚Ρ€Π°Π²ΠΌΠΎΠΉ Π³Ρ€ΡƒΠ΄ΠΈ, госпитализированных Π² экстрСнном порядкС Π² ΠΏΠ΅Ρ€ΠΈΠΎΠ΄ с 1 января 2020 ΠΏΠΎ август 2021 Π³ΠΎΠ΄Π°; 55 ΠΏΠ°Ρ†ΠΈΠ΅Π½Ρ‚ΠΎΠ² Π² Ρ…ΠΎΠ΄Π΅ лСчСния ΠΏΠΎΠ»ΡƒΡ‡ΠΈΠ»ΠΈ ΠΎΠ±Π΅Π·Π±ΠΎΠ»ΠΈΠ²Π°ΡŽΡ‰ΡƒΡŽ Ρ‚Π΅Ρ€Π°ΠΏΠΈΡŽ Π² Π²ΠΈΠ΄Π΅ ΠΏΠ°Ρ€Π°Π²Π΅Ρ€Ρ‚Π΅Π±Ρ€Π°Π»ΡŒΠ½ΠΎΠΉ Π±Π»ΠΎΠΊΠ°Π΄Ρ‹. Π’ Π³Ρ€ΡƒΠΏΠΏΡƒ сравнСния Π²ΠΊΠ»ΡŽΡ‡ΠΈΠ»ΠΈ 660 ΠΏΠ°Ρ†ΠΈΠ΅Π½Ρ‚ΠΎΠ², ΠΊΠΎΡ‚ΠΎΡ€Ρ‹ΠΌ Π½Π΅ выполняли ΠΏΡ€ΠΎΠ²ΠΎΠ΄Π½ΠΈΠΊΠΎΠ²ΡƒΡŽ Π±Π»ΠΎΠΊΠ°Π΄Ρƒ, ΠΎΠ±Π΅Π·Π±ΠΎΠ»ΠΈΠ²Π°Π½ΠΈΠ΅ обСспСчивали систСмным Π²Π²Π΅Π΄Π΅Π½ΠΈΠ΅ΠΌ Π°Π½Π°Π»ΡŒΠ³Π΅Ρ‚ΠΈΠΊΠΎΠ². Π‘Ρ€Π°Π²Π½ΠΈΠ²Π°Π΅ΠΌΡ‹Π΅ Π³Ρ€ΡƒΠΏΠΏΡ‹ Π·Π½Π°Ρ‡ΠΈΠΌΠΎ Π½Π΅ ΠΎΡ‚Π»ΠΈΡ‡Π°Π»ΠΈΡΡŒ ΠΏΠΎ ΠΏΠΎΠ»ΠΎΠ²ΠΎΠΌΡƒ ΠΈ возрастному составу. ΠžΡ‚Π»ΠΈΡ‡ΠΈΠΉ Π² частотС хроничСских Π·Π°Π±ΠΎΠ»Π΅Π²Π°Π½ΠΈΠΉ ΠΈ ΠΈΠ½Ρ‚Ρ€Π°ΠΏΠ»Π΅Π²Ρ€Π°Π»ΡŒΠ½Ρ‹Ρ… ослоТнСний Ρ‚Π°ΠΊΠΆΠ΅ Π½Π΅ Π±Ρ‹Π»ΠΎ. Π—Π½Π°Ρ‡ΠΈΠΌΡ‹Ρ… ослоТнСний ΠΏΡ€ΠΈ Π²Ρ‹ΠΏΠΎΠ»Π½Π΅Π½ΠΈΠΈ Π±Π»ΠΎΠΊΠ°Π΄Ρ‹ Π½Π΅ ΠΎΡ‚ΠΌΠ΅Ρ‡Π°Π»ΠΎΡΡŒ. ΠŸΡ€ΠΈ сравнСнии выявлСно достовСрноС ΡƒΠΌΠ΅Π½ΡŒΡˆΠ΅Π½ΠΈΠ΅ частоты ΠΏΠ»Π΅Π²Ρ€ΠΈΡ‚Π° ΠΈ Π±ΠΎΠ»Π΅Π΅ ΠΊΠΎΡ€ΠΎΡ‚ΠΊΠΎΠ΅ врСмя нахоТдСния Π² стационарС. ΠŸΠ°Ρ€Π°Π²Π΅Ρ€Ρ‚Π΅Π±Ρ€Π°Π»ΡŒΠ½Π°Ρ Π±Π»ΠΎΠΊΠ°Π΄Π° являСтся эффСктивным ΠΈ бСзопасным ΠΌΠ΅Ρ‚ΠΎΠ΄ΠΎΠΌ обСзболивания ΠΏΠ°Ρ†ΠΈΠ΅Π½Ρ‚ΠΎΠ² с Π·Π°ΠΊΡ€Ρ‹Ρ‚ΠΎΠΉ Ρ‚Ρ€Π°Π²ΠΌΠΎΠΉ Π³Ρ€ΡƒΠ΄ΠΈ. ИспользованиС этой ΠΌΠ΅Ρ‚ΠΎΠ΄ΠΈΠΊΠΈ сниТаСт частоту развития посттравматичСского ΠΏΠ»Π΅Π²Ρ€ΠΈΡ‚Π° ΠΈ ускоряСт выписку Π±ΠΎΠ»ΡŒΠ½Ρ‹Ρ…

    Врансплантация Π»Π΅Π³ΠΊΠΈΡ… Ρƒ ΠΏΠ°Ρ†ΠΈΠ΅Π½Ρ‚Π° с эмфизСмой Π½Π° Ρ„ΠΎΠ½Π΅ Π΄Π΅Ρ„ΠΈΡ†ΠΈΡ‚Π° Ξ±1-антитрипсина

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    The condition of patients with chronic lung diseases is gradually deteriorating despite modern drug therapy and often progresses to severe respiratory failure. Thus, it is important to consider other options, including surgical methods, to help such patients. The aim of the study is to demonstrate potential additional pharmacological and surgical treatment algorithms for chronic obstructive pulmonary disease (COPD) associated with Ξ±1-anti-trypsin (A1AT) deficiency. Results. The analysis of long-term medical history (from the onset to the terminal stage of the respiratory failure) of a patient with A1AT deficiency was performed. Conclusion. Patients with COPD associated with A1AT deficiency require combination inhaled controller therapy and augmentation therapy with a1-proteinase inhibitor. Patients with terminal stage of the disease need lung transplantation unless they have any contraindications.НСсмотря Π½Π° ΡΠΎΠ²Ρ€Π΅ΠΌΠ΅Π½Π½ΡƒΡŽ ΠΌΠ΅Π΄ΠΈΠΊΠ°ΠΌΠ΅Π½Ρ‚ΠΎΠ·Π½ΡƒΡŽ Ρ‚Π΅Ρ€Π°ΠΏΠΈΡŽ, состояниС ΠΌΠ½ΠΎΠ³ΠΈΡ… ΠΏΠ°Ρ†ΠΈΠ΅Π½Ρ‚ΠΎΠ² с хроничСскими заболСваниями Π»Π΅Π³ΠΊΠΈΡ… постСпСнно ΡƒΡ…ΡƒΠ΄ΡˆΠ°Π΅Ρ‚ΡΡ, Π½Π΅Ρ€Π΅Π΄ΠΊΠΎ это ΠΏΡ€ΠΈΠ²ΠΎΠ΄ΠΈΡ‚ ΠΊ Ρ€Π°Π·Π²ΠΈΡ‚ΠΈΡŽ тяТСлой Π΄Ρ‹Ρ…Π°Ρ‚Π΅Π»ΡŒΠ½ΠΎΠΉ нСдостаточности. ΠŸΡ€ΠΈ этом Π²Π°ΠΆΠ½ΠΎ Ρ€Π°ΡΡΠΌΠ°Ρ‚Ρ€ΠΈΠ²Π°Ρ‚ΡŒ Π΄ΠΎΠΏΠΎΠ»Π½ΠΈΡ‚Π΅Π»ΡŒΠ½Ρ‹Π΅ возмоТности ΠΏΠΎΠΌΠΎΡ‰ΠΈ Ρ‚Π°ΠΊΠΈΠΌ ΠΏΠ°Ρ†ΠΈΠ΅Π½Ρ‚Π°ΠΌ, Π² Ρ‚. Ρ‡. хирургичСскиС. ЦСлью исслСдования явилась дСмонстрация Π²ΠΎΠ·ΠΌΠΎΠΆΠ½Ρ‹Ρ… Π΄ΠΎΠΏΠΎΠ»Π½ΠΈΡ‚Π΅Π»ΡŒΠ½Ρ‹Ρ… ΠΌΠ΅Π΄ΠΈΠΊΠ°ΠΌΠ΅Π½Ρ‚ΠΎΠ·Π½Ρ‹Ρ… ΠΈ хирургичСских способов лСчСния ΠΏΠ°Ρ†ΠΈΠ΅Π½Ρ‚ΠΎΠ² с хроничСской обструктивной болСзнью Π»Π΅Π³ΠΊΠΈΡ… (Π₯ΠžΠ‘Π›) Π½Π° Ρ„ΠΎΠ½Π΅ Π΄Π΅Ρ„ΠΈΡ†ΠΈΡ‚Π° Ξ±1-антитрипсина (А1АВ). Π Π΅Π·ΡƒΠ»ΡŒΡ‚Π°Ρ‚Ρ‹. Π’Ρ‹ΠΏΠΎΠ»Π½Π΅Π½ Π°Π½Π°Π»ΠΈΠ· ΠΌΠ½ΠΎΠ³ΠΎΠ»Π΅Ρ‚Π½Π΅Π³ΠΎ Π°Π½Π°ΠΌΠ½Π΅Π·Π° ΠΏΠ°Ρ†ΠΈΠ΅Π½Ρ‚Π° с Π΄Π΅Ρ„ΠΈΡ†ΠΈΡ‚ΠΎΠΌ А1АВ ΠΎΡ‚ Π΄Π΅Π±ΡŽΡ‚Π° заболСвания Π΄ΠΎ достиТСния Ρ‚Π΅Ρ€ΠΌΠΈΠ½Π°Π»ΡŒΠ½ΠΎΠΉ стадии Π΄Ρ‹Ρ…Π°Ρ‚Π΅Π»ΡŒΠ½ΠΎΠΉ нСдостаточности. Π—Π°ΠΊΠ»ΡŽΡ‡Π΅Π½ΠΈΠ΅. ΠŸΠ°Ρ†ΠΈΠ΅Π½Ρ‚Ρ‹ с Π₯ΠžΠ‘Π› Π½Π° Ρ„ΠΎΠ½Π΅ Π΄Π΅Ρ„ΠΈΡ†ΠΈΡ‚Π° А1АВ Π½ΡƒΠΆΠ΄Π°ΡŽΡ‚ΡΡ Π² ΠΊΠΎΠΌΠ±ΠΈΠ½ΠΈΡ€ΠΎΠ²Π°Π½Π½ΠΎΠΉ ингаляционной базисной Ρ‚Π΅Ρ€Π°ΠΏΠΈΠΈ ΠΈ Π·Π°ΠΌΠ΅ΡΡ‚ΠΈΡ‚Π΅Π»ΡŒΠ½ΠΎΠΉ Ρ‚Π΅Ρ€Π°ΠΏΠΈΠΈ ΠΈΠ½Π³ΠΈΠ±ΠΈΡ‚ΠΎΡ€ΠΎΠΌ Ξ±1-ΠΏΡ€ΠΎΡ‚Π΅ΠΈΠ½Π°Π·Ρ‹. По достиТСнии Ρ‚Π΅Ρ€ΠΌΠΈΠ½Π°Π»ΡŒΠ½ΠΎΠΉ стадии заболСвания ΠΈ ΠΏΡ€ΠΈ отсутствии ΠΏΡ€ΠΎΡ‚ΠΈΠ²ΠΎΠΏΠΎΠΊΠ°Π·Π°Π½ΠΈΠΉ Π½Π΅ΠΎΠ±Ρ…ΠΎΠ΄ΠΈΠΌΠΎ Π²Ρ‹ΠΏΠΎΠ»Π½Π΅Π½ΠΈΠ΅ трансплантации Π»Π΅Π³ΠΊΠΈΡ…

    Predictors of using extracorporeal membrane oxygenation in lung transplantation

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    Rationale. Lung transplantation is the only definitive treatment in end-stage pulmonary disease. Extracorporeal membrane oxygenation (ECMO) has been used during surgery in recent years as a replacement for respiratory function; ECMO, however, has some drawbacks: the presence of an extracorporeal circuit, the need for heparinization, potential thrombogenicity that underlies the risks of developing specific complications that worsen the transplantation prognosis. In this regard, it is relevant to study the factors that make it possible to predict the need in intraoperative ECMO in order to avoid its unjustified use.Purpose. To identify predictors for intraoperative use of ECMO in lung transplantation.Material and methods. The medical records of patients who underwent lung transplantation in the Sklifosovsky Research Institute for Emergency Medicine from May 2011 to July 2017 were retrospectively reviewed. Forty nine bilateral lung transplantations were made where 15 patients (30.6%) had lung transplantation performed without ECMO, and 34 (69.4%) underwent lung transplantation and ECMO. A central veno-arterial connection was used in all patients. The study analyzed various factors of patient condition at baseline and identified the most significant of them that enabled to predict the need of ECMO use at surgery with a high degree of probability, avoiding episodes of gas exchange and hemodynamic impairments, the prolongation of surgery, and, therefore, the graft ischemia time.Results. As assessed in this study, pulmonary hypertension was the only predictor of an increased likelihood of using ECMO. The probability of connection to ECMO statistically significantly increased in the patients with systolic pulmonary artery pressure higher 50 mm Hg (p<0.05).Conclusion. The presence of pulmonary hypertension > 50 mm Hg determines the preventive use of ECMO during lung transplantation, which should reduce the number of uncontrolled emergencies during the main stages of surgical intervention; in all other cases, ECMO should be connected basing either on the pulmonary artery compression test results or when indicated
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