8,306 research outputs found

    Grid Cells Form a Global Representation of Connected Environments.

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    The firing patterns of grid cells in medial entorhinal cortex (mEC) and associated brain areas form triangular arrays that tessellate the environment [1, 2] and maintain constant spatial offsets to each other between environments [3, 4]. These cells are thought to provide an efficient metric for navigation in large-scale space [5-8]. However, an accurate and universal metric requires grid cell firing patterns to uniformly cover the space to be navigated, in contrast to recent demonstrations that environmental features such as boundaries can distort [9-11] and fragment [12] grid patterns. To establish whether grid firing is determined by local environmental cues, or provides a coherent global representation, we recorded mEC grid cells in rats foraging in an environment containing two perceptually identical compartments connected via a corridor. During initial exposures to the multicompartment environment, grid firing patterns were dominated by local environmental cues, replicating between the two compartments. However, with prolonged experience, grid cell firing patterns formed a single, continuous representation that spanned both compartments. Thus, we provide the first evidence that in a complex environment, grid cell firing can form the coherent global pattern necessary for them to act as a metric capable of supporting large-scale spatial navigation

    A comparison of the responses of mature and young clonal tea to drought.

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    To assist commercial producers with optimising the use of irrigation water, the responses to drought of mature and young tea crops (22 and 5 years after field planting respectively) were compared using data from two adjacent long-term irrigation experiments in Southern Tanzania. Providing the maximum potential soil water deficit was below about 400-500 mm for mature, and 200-250 mm for young plants (clone 6/8), annual yields of dry tea from rainfed or partially irrigated crops were similar to those from the corresponding well-watered crops. At deficits greater than this, annual yields declined rapidly in young tea (up to 22 kg (ha mm)-1) but relatively slowly in mature tea (up to 6.5 kg (ha mm)- 1). This apparent insensitivity of the mature crop to drought was due principally to compensation that occurred during the rains for yield lost in the dry season. Differences in dry matter distribution and shoot to root ratios contributed to these contrasting responses. Thus, the total above ground dry mass of well-irrigated, mature plants was about twice that for young plants. Similarly, the total mass of structural roots (>1 mm diameter), to 3 m depth, was four times greater in the mature crop than in the young crop and, for fine roots (<1 mm diameter), eight times greater. The corresponding shoot to root ratios (dry mass) were about 1:1 and 2:1 respectively. In addition, each unit area of leaf in the canopy of a mature plant had six times more fine roots (by weight) available to extract and supply water than did a young plant. Despite the logistical benefits resulting from more even crop distribution during the year when crops are fully irrigated, producers currently prefer to save water and energy costs by allowing a substantial soil water deficit to develop prior to the start of the rains, up to 250 mm in mature tea, knowing that yield compensation will occur later

    235 Using HbAlc and random blood glucose to screen for cystic fibrosis related diabetes (CFRD)

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    Sculpting the Extra Dimensions: Inflation from Codimension-2 Brane Back-reaction

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    We construct an inflationary model in 6D supergravity that is based on explicit time-dependent solutions to the full higher-dimensional field equations, back-reacting to the presence of a 4D inflaton rolling on a space-filling codimension-2 source brane. Fluxes in the bulk stabilize all moduli except the `breathing' modulus (that is generically present in higher-dimensional supergravities). Back-reaction to the inflaton roll causes the 4D Einstein-frame on-brane geometry to expand, a(t) ~ t^p, as well as exciting the breathing mode and causing the two off-brane dimensions to expand, r(t) ~ t^q. The model evades the general no-go theorems precluding 4D de Sitter solutions, since adjustments to the brane-localized inflaton potential allow the power p to be dialed to be arbitrarily large, with the 4D geometry becoming de Sitter in the limit p -> infinity (in which case q = 0). Slow-roll solutions give accelerated expansion with p large but finite, and q = 1/2. Because the extra dimensions expand during inflation, the present-day 6D gravity scale can be much smaller than it was when primordial fluctuations were generated - potentially allowing TeV gravity now to be consistent with the much higher gravity scale required at horizon-exit for observable primordial gravity waves. Because p >> q, the 4 on-brane dimensions expand more quickly than the 2 off-brane ones, providing a framework for understanding why the observed four dimensions are presently so much larger than the internal two. If uplifted to a 10D framework with 4 dimensions stabilized, the 6D evolution described here could describe how two of the six extra dimensions evolve to become much larger than the others, as a consequence of the enormous expansion of the 4 large dimensions we can see.Comment: 27 pages + appendices, 2 figure

    D-Brane Dynamics and NS5 Rings

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    We consider the classical motion of a probe D-brane moving in the background geometry of a ring of NS5 branes, assuming that the latter are non-dynamical. We analyse the solutions to the Dirac-Born-Infield (DBI) action governing the approximate dynamics of the system. In the near horizon (throat) approximation we find several exact solutions for the probe brane motion. These are compared to numerical solutions obtained in more general cases. One solution of particular interest is when the probe undergoes oscillatory motion through the centre of the ring (and perpendicular to it). By taking the ring radius sufficiently large, this solution should remain stable to any stringy corrections coming from open-strings stretching between the probe and the NS5-branes along the ring.Comment: 17 pages, Latex, 8 figures; References adde

    DBI Lifshitz Inflation

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    A new model of DBI inflation is introduced where the mobile brane, the inflaton field, is moving relativistically inside a Lifshitz throat with an arbitrary anisotropic scaling exponent zz. After dimensional reduction to four dimension the general covariance is broken explicitly both in the matter and the gravitational sectors. The general action for the metric and matter field perturbations are obtained and it is shown to be similar to the classifications made in the effective field theory of inflation literature.Comment: Version 3: minor typos corrected, the JCAP published versio

    Atomic data from the IRON Project. I. Electron-impact scattering of Fe17+ using <I>R</I>-matrix theory with intermediate coupling

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    We present results for electron-impact excitation of F-like Fe calculated using R-matrix theory where an intermediate-coupling frame transformation (ICFT) is used to obtain level-resolved collision strengths. Two such calculations are performed, the first expands the target using 2s2 2p5, 2s 2p6, 2s2 2p4 3l, 2s 2p5 3l, and 2p6 3l configurations while the second calculation includes the 2s2 2p4 4l, 2s 2p5 4l, and 2p6 4l configurations as well. The effect of the additional structure in the latter calculation on the n=3 resonances is explored and compared with previous calculations. We find strong resonant enhancement of the effective collision strengths to the 2s2 2p4 3s levels. A comparison with a Chandra X-ray observation of Capella shows that the n=4 R-matrix calculation leads to good agreement with observation</p

    Bulk Axions, Brane Back-reaction and Fluxes

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    Extra-dimensional models can involve bulk pseudo-Goldstone bosons (pGBs) whose shift symmetry is explicitly broken only by physics localized on branes. Reliable calculation of their low-energy potential is often difficult because it requires details of the stabilization of the extra dimensions. In rugby ball solutions, for which two compact extra dimensions are stabilized in the presence of only positive-tension brane sources, the effects of brane back-reaction can be computed explicitly. This allows the calculation of the shape of the low-energy pGB potential and response of the extra dimensional geometry as a function of the perturbing brane properties. If the pGB-dependence is a small part of the total brane tension a very general analysis is possible, permitting an exploration of how the system responds to frustration when the two branes disagree on what the proper scalar vacuum should be. We show how the low-energy potential is given by the sum of brane tensions (in agreement with common lore) when only the brane tensions couple to the pGB. We also show how a direct brane coupling to the flux stabilizing the extra dimensions corrects this result in a way that does not simply amount to the contribution of the flux to the brane tensions. We calculate the mass of the would-be zero mode, and briefly describe several potential applications, including a brane realization of `natural inflation,' and a dynamical mechanism for suppressing the couplings of the pGB to matter localized on the branes. Since the scalar can be light enough to be relevant to precision tests of gravity (in a technically natural way) this mechanism can be relevant to evading phenomenological bounds.Comment: 36 pages, JHEP styl

    MSSM Higgses as the source of reheating and all matter

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    We consider the possibility that the dark energy responsible for inflation is deposited into extra dimensions outside of our observable universe. Reheating and all matter can then be obtained from the MSSM flat direction condensate involving the Higgses HuH_u and HdH_d, which acquires large amplitude by virtue of quantum fluctuations during inflation. The reheat temperature is TRHâ‰Č109T_{RH} \lesssim 10^9 GeV so that there is no gravitino problem. We find a spectral index ns≈1n_s\approx 1 with a very weak dependence on the Higgs potential.Comment: 4 page
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