20 research outputs found

    Photosynthate Partitioning into Starch in Soybean Leaves

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    Nonstructural carbohydrates in tall fescue cultivars: Relationship to animal preference

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    Grazing animals prefer some plants to others. These choices are likely related to physical and chemical factors such as energy-dense carbohydrates contained in plants. This study quantified the nonstructural carbohydrate fractions in each of eight vegetatively growing, endophyte-free, tall fescue cultivars (Festuca arundinacea Schreb.) and relates their sugar concentrations to cattle grazing preferences. The experimental area consisted of eight cultivar plots replicated three times in each of three pastures. Within each pasture, forage was sampled between 0830 and 1000 h mountain daylight time (MDT) during each of four seasons and 2 yr. Freeze-dried forage samples were extracted with hot water and an amylase (Clarase) solution. Sugars were quantified colorimetrically using potassium-ferricyanide and glucose-oxidase methods. Cattle grazing preferences among these tall fescue cultivars were related to the concentrations of total nonstructural carbohydrates (TNC) (r2 = 0.49, P < 0.05). Other sugar fractions were not significantly related to grazing preference in this study. The nonstructural carbohydrate concentrations averaged over the entire study were glucose, 14; fructose, 5; sucrose, 40; fructan, 23; insoluble starch, 24; and TNC, 129 g kg-1. A forage selection criterion should include measures of the TNC because of their close relationship to animal grazing preference

    Dimethyl fumarate in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial

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    Dimethyl fumarate (DMF) inhibits inflammasome-mediated inflammation and has been proposed as a treatment for patients hospitalised with COVID-19. This randomised, controlled, open-label platform trial (Randomised Evaluation of COVID-19 Therapy [RECOVERY]), is assessing multiple treatments in patients hospitalised for COVID-19 (NCT04381936, ISRCTN50189673). In this assessment of DMF performed at 27 UK hospitals, adults were randomly allocated (1:1) to either usual standard of care alone or usual standard of care plus DMF. The primary outcome was clinical status on day 5 measured on a seven-point ordinal scale. Secondary outcomes were time to sustained improvement in clinical status, time to discharge, day 5 peripheral blood oxygenation, day 5 C-reactive protein, and improvement in day 10 clinical status. Between 2 March 2021 and 18 November 2021, 713 patients were enroled in the DMF evaluation, of whom 356 were randomly allocated to receive usual care plus DMF, and 357 to usual care alone. 95% of patients received corticosteroids as part of routine care. There was no evidence of a beneficial effect of DMF on clinical status at day 5 (common odds ratio of unfavourable outcome 1.12; 95% CI 0.86-1.47; p = 0.40). There was no significant effect of DMF on any secondary outcome

    Dimethyl fumarate in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial

    Get PDF
    Dimethyl fumarate (DMF) inhibits inflammasome-mediated inflammation and has been proposed as a treatment for patients hospitalised with COVID-19. This randomised, controlled, open-label platform trial (Randomised Evaluation of COVID-19 Therapy [RECOVERY]), is assessing multiple treatments in patients hospitalised for COVID-19 (NCT04381936, ISRCTN50189673). In this assessment of DMF performed at 27 UK hospitals, adults were randomly allocated (1:1) to either usual standard of care alone or usual standard of care plus DMF. The primary outcome was clinical status on day 5 measured on a seven-point ordinal scale. Secondary outcomes were time to sustained improvement in clinical status, time to discharge, day 5 peripheral blood oxygenation, day 5 C-reactive protein, and improvement in day 10 clinical status. Between 2 March 2021 and 18 November 2021, 713 patients were enroled in the DMF evaluation, of whom 356 were randomly allocated to receive usual care plus DMF, and 357 to usual care alone. 95% of patients received corticosteroids as part of routine care. There was no evidence of a beneficial effect of DMF on clinical status at day 5 (common odds ratio of unfavourable outcome 1.12; 95% CI 0.86-1.47; p = 0.40). There was no significant effect of DMF on any secondary outcome

    Atriplex polycarpa

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    Photosynthate Partitioning into Starch in Soybean Leaves

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    Range Plant Development In Utah: A Historical View

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