22 research outputs found
The effect of tigecycline and ertapenem against clinical isolates of Brucella melitensis detected by E-test on different media
In this study, in vitro activity of tigecycline (TIG) and ertapenem
(ERT) against clinical isolates of Brucella melitensis and the effect
of different media on in vitro test results were investigated. The in
vitro effects of TIG and ERT to 38 B. melitensis isolates were
comparatively investigated in brucella agar and 5% sheep blood agar.
MIC value of ERT was 0.032 μg/mL in 23 of 38 and 20 of 38 isolates
on blood and brucella agar, respectively. Minimum inhibitory
concentration values of TIG were substantially different ranging
between 0.064-0.25 μg/mL on blood agar. However, MIC values of TIG
were similar on brucella agar with 0.25 μg/mL in 15 of 38 isolates
and 0.5 μg/mL in 10 of 38 isolates. In conclusion, although ERT
and TIG were effective against B. melitensis isolates in vitro, further
studies are needed in order to determine the use of these novel drugs
in treatment of brucellosis
Predictors of fatality in influenza A virus subtype infections among inpatients in the 2015-2016 season
Background: Infection with the influenza A virus can cause severe disease and mortality. The effect of the different subtypes of influenza on morbidity and mortality is not yet known in Turkey. The aim of this study was to describe the predictors of fatality related to influenza A infection among hospitalized patients in Istanbul during the 2015-2016 influenza season, and to detail the differences between infections caused by H3N2 and H1N1