13 research outputs found
Amyloid β-protein oligomers upregulate the β-secretase, BACE1, through a post-translational mechanism involving its altered subcellular distribution in neurons
Full text linkCeylonins G–I: spongian diterpenes from the marine sponge Spongia ceylonensis
Get PDFThree new spongian diterpenes, ceylonins G–I (1–3), were isolated from the marine sponge Spongia ceylonensis collected in Indonesia, together with five known spongian diterpenes (4–8). Only 4 inhibited USP7 with an IC50 value of 8.2 μM
Thrombospondin-1 secreted by human umbilical cord blood-derived mesenchymal stem cells rescues neurons from synaptic dysfunction in Alzheimer’s disease model
No full textThe neurotoxicity of amyloid β-protein oligomers is reversible in a primary neuron model
No full textRestoring synaptic plasticity and memory in mouse models of Alzheimer’s disease by PKR inhibition
No full textMagnetic Properties of 1:2 Mixed Cobalt(II) Salicylaldehyde Schiff-Base Complexes with Pyridine Ligands Carrying High-Spin Carbenes ( S
No full textAstrocytes infected with Chlamydia pneumoniae demonstrate altered expression and activity of secretases involved in the generation of β-amyloid found in Alzheimer disease
No full textIL-1β suppresses cLTP-induced surface expression of GluA1 and actin polymerization via ceramide-mediated Src activation
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Assessment of cognitive and neural recovery in survivors of pediatric brain tumors in a pilot clinical trial using metformin
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