856 research outputs found
Wyman's solution, self-similarity and critical behaviour
We show that the Wyman's solution may be obtained from the four-dimensional
Einstein's equations for a spherically symmetric, minimally coupled, massless
scalar field by using the continuous self-similarity of those equations. The
Wyman's solution depends on two parameters, the mass and the scalar charge
. If one fixes to a positive value, say , and let
take values along the real line we show that this solution exhibits critical
behaviour. For the space-times have eternal naked singularities,
for one has a Schwarzschild black hole of mass and finally
for one has eternal bouncing solutions.Comment: Revtex version, 15pages, 6 figure
First Detection of Ar-K Line Emission from the Cygnus Loop
We observed the Cygnus Loop with XMM-Newton (9 pointings) and Suzaku (32
pointings) between 2002 and 2008. The total effective exposure time is 670.2
ks. By using all of the available data, we intended to improve a
signal-to-noise ratio of the spectrum. Accordingly, the accumulated spectra
obtained by the XIS and the EPIC show some line features around 3 keV that are
attributed to the S He and Ar He lines, respectively. Since the
Cygnus Loop is an evolved (10,000 yr) supernova remnant whose temperature
is relatively low (1 keV) compared with other young remnants, its spectrum
is generally faint above 3.0 keV, no emission lines, such as the Ar-K line have
ever been detected. The detection of the Ar-K line is the first time and we
found that its abundance is significantly higher than that of the solar value;
9.0 and 8.4 (in units of solar), estimated from
the XIS and the EPIC spectra, respectively. We conclude that the Ar-K line
originated from the ejecta of the Cygnus Loop. Follow-up X-ray observations to
tightly constrain the abundances of Ar-rich ejecta will be useful to accurately
estimate the progenitor's mass.Comment: 12 pages, 9 figures, accepted for publication in PAS
Development of geothermal field following the 2000 eruption of Usu volcano as revealed by ground temperature, resistivity and self-potential variations
The 2000 eruption of Usu volcano, NE Japan, took place on the foot of the somma, and formed a cryptodome
of 65 m high accompanying numerous faults. We made repeated measurements of ground temperature, Self-Potential
(SP) and electrical resistivity, in order to clarify the mechanism of development of the newly formed geothermal
field on the fault zone. Prior to the expansion of the geothermal field, we detected a resistive zone at
the center of the geothermal zone and it supposed to evidence that the zone involving dry steam phase had been
formed beneath the fault zone. A rapid expansion of the geothermal field followed along the fault zone away
from the craters. The place of maximum amplitude of the SP field also migrated following the expansion of the
high ground temperature zone. The high resistive part has shrunk as a consequence of the progress of condensation
to warm the surroundings. Based on the observations, we delineated the process of the hydrothermal circulation.
Considering the topographic effect of the SP field observed on the highly permeable zone in the Usu somma,
the potential flow along the slope of the soma was expected to play an important role to promote the rapid
expansion of the geothermal field and the migration of the most active part
Spontaneous Bacterial Pericarditis and Coronary Sinus Endocarditis Caused by Oxacillin-Susceptible Staphylococcus aureus
This paper describes a case of a 44-year-old male patient previously healthy admitted with an unusual spontaneous acute bacterial pericarditis associated with coronary sinus mass. Two-dimensional echocardiography showed large loculated pericardial effusion with signs of diastolic restriction and an image suggesting vegetation in topography of the right atrium coronary sinus. Pericardial drainage, coronary sinus vegetation resection, and antibiotic therapy with Oxacillin were performed due to Oxacillin-susceptible Staphylococcus aureus identified on the pericardial effusion and blood culture. This is a rare condition and a unique combination of a spontaneous acute bacterial pericarditis with coronary sinus endocarditis without cardiac valve compromise
Duality through the symplectic embedding formalism
In this work we show that we can obtain dual equivalent actions following the
symplectic formalism with the introduction of extra variables which enlarge the
phase space. We show that the results are equal as the one obtained with the
recently developed gauging iterative Noether dualization method (NDM). We
believe that, with the arbitrariness property of the zero mode, the symplectic
embedding method (SEM) is more profound since it can reveal a whole family of
dual equivalent actions. We illustrate the method demonstrating that the
gauge-invariance of the electromagnetic Maxwell Lagrangian broken by the
introduction of an explicit mass term and a topological term can be restored to
obtain the dual equivalent and gauge-invariant version of the theory.Comment: RevTeX4, 10 pages. To appear in Int. J. Mod. Phys.
Circulation Statistics in Three-Dimensional Turbulent Flows
We study the large limit of the loop-dependent characteristic
functional , related
to the probability density function (PDF) of the circulation around a closed
contour . The analysis is carried out in the framework of the
Martin-Siggia-Rose field theory formulation of the turbulence problem, by means
of the saddle-point technique. Axisymmetric instantons, labelled by the
component of the strain field -- a partially annealed variable in
our formalism -- are obtained for a circular loop in the plane, with
radius defined in the inertial range. Fluctuations of the velocity field around
the saddle-point solutions are relevant, leading to the lorentzian asymptotic
behavior . The
subleading correction and the asymmetry between right and left PDF tails due to
parity breaking mechanisms are also investigated.Comment: Computations are discussed in a more detailed way; accepted for
publication in Physical Review
Characterization of a half-wave plate for cosmic microwave background circular polarization measurement with POLARBEAR
A half-wave plate (HWP) is often used as a modulator to suppress systematic
error in the measurements of cosmic microwave background (CMB) polarization. A
HWP can also be used to measure circular polarization (CP) through its optical
leakage from CP to linear polarization. The CP of the CMB is predicted from
various sources, such as interactions in the Universe and extension of the
standard model. Interaction with supernova remnants of population III stars is
one of the brightest CP sources. Thus, the observation of the CP of CMB is a
new tool for searching for population III stars. In this paper, we demonstrate
the improved measurement of the leakage coefficient using the transmission
measurement of an actual HWP in the laboratory. We measured the transmittance
of linearly polarized light through the HWP used in \textsc{Polarbear} in the
frequency range of \SIrange{120}{160}{GHz}. We evaluate properties of the HWP
by fitting the data with a physical model using the Markov Chain Monte Carlo
method. We then estimate the band-averaged CP leakage coefficient using the
physical model. We find that the leakage coefficient strongly depends on the
spectra of CP sources. We thus calculate the maximum fractional leakage
coefficient from CP to linear polarization as in the
Rayleigh--Jeans spectrum. The nonzero value shows that \textsc{Polarbear} has
sensitivity to CP. Additionally, because we use the bandpass of detectors
installed in the telescope to calculate the band-averaged values, we also
consider systematic effects in the experiment.Comment: 27 pages, 7 figure
Domain Walls in a FRW Universe
We solve the equations of motion for a scalar field with domain wall boundary
conditions in a Friedmann-Robertson-Walker (FRW) spacetime. We find (in
agreement with Basu and Vilenkin) that no domain wall solutions exist in de
Sitter spacetime for h = H/m >= 1/2, where H is the Hubble parameter and m is
the scalar mass. In the general FRW case we develop a systematic perturbative
expansion in h to arrive at an approximate solution to the field equations. We
calculate the energy momentum tensor of the domain wall configuration, and show
that the energy density can become negative at the core of the defect for some
values of the non-minimal coupling parameter xi. We develop a translationally
invariant theory for fluctuations of the wall, obtain the effective Lagrangian
for these fluctuations, and quantize them using the Bunch-Davies vacuum in the
de Sitter case. Unlike previous analyses, we find that the fluctuations act as
zero-mass (as opposed to tachyonic) modes. This allows us to calculate the
distortion and the normal-normal correlators for the surface. The normal-normal
correlator decreases logarithmically with the distance between points for large
times and distances, indicating that the interface becomes rougher than in
Minkowski spacetime.Comment: 23 pages, LaTeX, 7 figures using epsf.tex. Now auto-generates P
Intraperitoneal administration of telomerase-specific oncolytic adenovirus sensitizes ovarian cancer cells to cisplatin and affects survival in a xenograft model with peritoneal dissemination
Despite tremendous development in chemotherapy for ovarian cancer over the past few decades, the prognosis of advanced cases with massive peritoneal dissemination is still unsatisfactory, and novel treatment modalities that can combine with chemotherapy are urgently needed. We recently developed virotherapy for solid tumors using telomerase-specific replication-selective adenoviruses (Telomelysin: OBP-301), in which the human telomerase reverse transcriptase (hTERT) gene promoter has been inserted to direct tumor-specific E1 gene expression. In this study, we investigated the anti-tumor effects of OBP-301, combined with cisplatin (CDDP), on ovarian cancer cells. In vitro treatment of SKOV3 cells with OBP-301 at a multiplicity of infection (MOI) of 0.01–100 induced significant cell death in a dose-dependent manner, with moderate cytotoxicity at an MOI of 1–10 and maximal cytotoxicity at an MOI of 100. In contrast, OBP-301 treatment of normal human cells showed no significant cell death at an MOI of 1–10 and exhibited modest cytotoxicity at an MOI of 100. The effects of low-dose CDDP at 0.5–1 μM, which induced only 20% cell death, were significantly augmented by combination with OBP-301 at an MOI of 1–10, finally achieving 40% cell death. Such enhancement of CDDP sensitivity was also observed in CDDP-resistant ovarian cancer cells. The combinatorial effects were further tested using a xenograft mouse model of SKOV3 with peritoneal dissemination. After intraperitoneal administration of OBP-301, we confirmed that injected OBP-301 fused with the green fluorescent protein (GFP) gene (OBP-401) was preferentially localized to peritoneal disseminations, as determined by fluorescence imaging. Treatment of mice with CDDP at low dose (0.5 mg kg–1) had modest effects, showing a 10% decrease in disseminations, whereas combination with intraperitoneal administration of OBP-301 at an MOI of 10 led to enhanced effects, achieving an approximately 80% decrease in disseminations. Kaplan–Meier analysis showed improved overall survival of mice treated with CDDP plus OBP-301 compared with CDDP alone. These findings support the therapeutic potential of intraperitoneal administration of OBP-301 to sensitize ovarian cancer cells to CDDP
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