S.11.1 Influence of digital ulcer healing on disability and daily activity limitations in SSc

Objective. We previously showed that DU significantly increased global and hand disability with a significant impact on activities of daily living (ADLs) and work disability. This study aims to evaluate the impact of digital ulcer (DU) healing on disability and daily activity limitations in SSc. Methods. From January 2008 and June 2009, we prospectively evaluated 189 SSc patients for DU history, disability, employment and occupational status during meetings of the French SSc Patient Association (n = 86, 45.5%) or during hospitalization (n = 103, 54.5%)1. Among the 60 patients with at least one active DU at baseline (M0), 40 patients were followed longitudinally over 6 (3) months. These patients were evaluated for DU history, global and hand disability, health-related quality of life (HRQoL), daily activity limitation and employment status. Results. The median (IQR) age was 57.5 (43.5-68) years and the median (IQR) disease duration was 8.3 (3-16.5) years. Twenty-two (55%) patients had diffuse SSc and 34 (85%) were females. At baseline, a mean of 2.9 (2.8) DU per patient was reported. Thirty-three (82.5%) patients had ischaemic DU, 7 (17.5%) patients had >1 DU associated with calcinosis and 13 (32.5%) patients had mechanical DU. Thirteen (32.5%) patients had >4 DU at baseline. Among the 40 patients, 16 (40%) patients showed complete ulcer healing. In these patients with DU, the presence of calcinosis was associated with a lower probability of healing (P = 0.03). Comparison between healed and no-healed DU patients showed an improvement of hand disability provided by an improvement of the Cochin Hand Function score (P = 0.05)) and a trend towards HAQ domain dressing and grooming (P = 0.06) between M0 and M6 (3) visit in healed patients but not in no-healed patients. Concerning HRQoL, there were no difference for Mental and Physical component Scores of SF-36 but significant improvement of Bodily Pain score (P = 0.04) and Physical Role score (P = 0.05) between M0 and M6 (3) visit in patients with healed DU. The absence of healing was associated with significantly decreased work productivity (P = 0.05), whereas the performance in ADL was not significantly decreased (P = 0.15). Patients who were on sick-leave and who received some help for household tasks at the time of active DU were more likely to heal. Conclusion. For the first time, we provide prospective data with evidence that DU healing is associated with an improvement in hand function. Sick leave was associated with better healing of D

Novel one-pot synthesis of mpg-C3N4 with metal/metal oxide nanoparticles

International @ MATERIAUX+EPU:ATUInternational audienceDue to many interesting properties such as high thermal and chemical stability polymeric graphitic carbon nitride found numerous applications in many fields of chemistry [1]. Recently, g-C3N4 have been reported to be effective and inexpensive photocatalyst for water splitting under visible light irradiation [2]. The performance of g-C3N4 as a photocatalyst could be improved by modification of textural properties or adjusting the electronic structure of C3N4 via doping with heteroelements. In the present work we have investigated the influence of synthesis route (hard templating method and condensation way of preparation with electron-deficient precursors) and the role of cocatalysts on the photocatalytic activity of mesoporous g-C3N4. Experimental Mesoporous g-C3N4 was prepared by two different strategies. In a hard templating method mesoporous silica KIT-6 was impregnated with cyanamide with the following calcination and removal of silica matrix. H2PtCl6-6H2O and Co(NO3)2-6H2O were introduced in functionalized KIT-6 before the cyanamide impregnation to form the nanoparticles of cocatalysts (Pt and Co3O4) inside the pores of KIT-6. The prepared KIT-6 material containing nanoparticles of cocatalysts with a size limited by the pore openings of KIT-6 was used as a hard template for the formation of mesoporous g-C3N4. The influence of synthesis methods (impregnation conditions, calcination temperature, conditions of cocatalyst incorporation and formation etc.) on crystalline and electronic structure of mpg-C3N4 has been investigated in details. Our second approach consisted in preparation of modified g-C3N4 via condensation of melem or melamine with electron-deficient precursors like pyromellitic dianhydride. This strategy allows to modify the band structure of g-C3N4 toward enhanced photooxidation/photoreduction properties. We systematically investigated the influence of structure of electron-deficient precursors on the electronic structure of g-C3N4. The photocatalytic activities of prepared samples have been determined for methanol dehydrogenation in comparison with Pt/TiO2. The influence of the preparation parameters on the activities will be discussed. Conclusions We developed an original way of preparation of mpg-C3N4 by replication of mesoporous silica KIT-6 containing cocatalyst nanoparticles in the pores of KIT-6. The strategy provides the better dispersion of cocatalyst nanoparticles in the mpg-C3N4 and leads to the creation of highly ordered 3-D materials with large surface area and photooxidation/photoreduction properties for water splitting. The second, "condensation" approach has been demonstrated to tune the band gap of g-C3N4 depending on the structure of electron-deficient precursors.[1] Q. Li, J. Yang, D. Feng, Z. Wu, Q. Wu, S. S. Park, C.-S. Ha, D. Zhao, Nano Res., 2010, 3, 632-642.[2] X. Wang, K. Maeda, A. Thomas, K. Takanabe, G. Xin, J.M. Carlsso, K. Domen, M. Antonietti, Nat Mater. 2009, 8(1), 76-80.</lu

Novel one-pot synthesis of mpg-C3N4 with metal/metal oxide nanoparticles

International @ MATERIAUX+EPU:ATUInternational audienceDue to many interesting properties such as high thermal and chemical stability polymeric graphitic carbon nitride found numerous applications in many fields of chemistry [1]. Recently, g-C3N4 have been reported to be effective and inexpensive photocatalyst for water splitting under visible light irradiation [2]. The performance of g-C3N4 as a photocatalyst could be improved by modification of textural properties or adjusting the electronic structure of C3N4 via doping with heteroelements. In the present work we have investigated the influence of synthesis route (hard templating method and condensation way of preparation with electron-deficient precursors) and the role of cocatalysts on the photocatalytic activity of mesoporous g-C3N4. Experimental Mesoporous g-C3N4 was prepared by two different strategies. In a hard templating method mesoporous silica KIT-6 was impregnated with cyanamide with the following calcination and removal of silica matrix. H2PtCl6-6H2O and Co(NO3)2-6H2O were introduced in functionalized KIT-6 before the cyanamide impregnation to form the nanoparticles of cocatalysts (Pt and Co3O4) inside the pores of KIT-6. The prepared KIT-6 material containing nanoparticles of cocatalysts with a size limited by the pore openings of KIT-6 was used as a hard template for the formation of mesoporous g-C3N4. The influence of synthesis methods (impregnation conditions, calcination temperature, conditions of cocatalyst incorporation and formation etc.) on crystalline and electronic structure of mpg-C3N4 has been investigated in details. Our second approach consisted in preparation of modified g-C3N4 via condensation of melem or melamine with electron-deficient precursors like pyromellitic dianhydride. This strategy allows to modify the band structure of g-C3N4 toward enhanced photooxidation/photoreduction properties. We systematically investigated the influence of structure of electron-deficient precursors on the electronic structure of g-C3N4. The photocatalytic activities of prepared samples have been determined for methanol dehydrogenation in comparison with Pt/TiO2. The influence of the preparation parameters on the activities will be discussed. Conclusions We developed an original way of preparation of mpg-C3N4 by replication of mesoporous silica KIT-6 containing cocatalyst nanoparticles in the pores of KIT-6. The strategy provides the better dispersion of cocatalyst nanoparticles in the mpg-C3N4 and leads to the creation of highly ordered 3-D materials with large surface area and photooxidation/photoreduction properties for water splitting. The second, "condensation" approach has been demonstrated to tune the band gap of g-C3N4 depending on the structure of electron-deficient precursors.[1] Q. Li, J. Yang, D. Feng, Z. Wu, Q. Wu, S. S. Park, C.-S. Ha, D. Zhao, Nano Res., 2010, 3, 632-642.[2] X. Wang, K. Maeda, A. Thomas, K. Takanabe, G. Xin, J.M. Carlsso, K. Domen, M. Antonietti, Nat Mater. 2009, 8(1), 76-80.</lu

PHOTOCATALYTIC TEXTILES: DEGRADATION OF BODY ODORS FOR SPORTSWEARS

International @ EAU+CRL:EPU:CGUInternational audienceNon

Influence of thermal treatments on phase composition and acidity of mesoporous tungsten oxides

International @ MATERIAUX+NKS:EPU:ATUInternational audienceTungsten trioxide has attracted much attention because of its unique photo-, thermo-, gaso- and electrochromic properties. Wide range of application of tungsten trioxide requires both high crystallinity as well as large surface area. In the present work we have investigated the influence of thermal treatments (calcination and treatment in reducing environment) on phase composition, crystallization and acidity of mesoporous tungsten oxides prepared via hard templating method. The acidity of WO3 materials was studied by pyridine adsorption-desorption method and chemisorption of probe molecules (CO, H2)

Photocatalysis: a green technology for methylamine and dimethylamine degradation: kinetic of adsorption and photocatalytic degradation.

internationa

Degradation photocatalytique d'un mélange de deux colorants anioniques

nationa

Photocatalytic degradation of methylamine and dimethylamine.

internationa