PEN experiment: a precise measurement of the pi+ -> e+ nu decay branching fraction

A new measurement of $B_{\pi e2}$, the $\pi^+ \to e^+\nu(\gamma)$ decay branching ratio, is currently under way at the Paul Scherrer Institute. The present experimental result on $B_{\pi e2}$ constitutes the most accurate test of lepton universality available. The accuracy, however, still lags behind the theoretical precision by over an order of magnitude. Because of the large helicity suppression of the $\pi_{e2}$ decay, its branching ratio is susceptible to significant contributions from new physics, making this decay a particularly suitable subject of study.Comment: 4 pages, 3 figures, talk given at the Tenth Conference on the Intersections of Particle and Nuclear Physics (CIPANP 2009), La Jolla/San Diego, CA, 26-31 May 2009; to appear in Proceedings to be published by the American Institute of Physic

PEN: a low energy test of lepton universality

Allowed charged $\pi$ meson decays are characterized by simple dynamics, few available decay channels, mainly into leptons, and extremely well controlled radiative and loop corrections. In that sense, pion decays represent a veritable triumph of the standard model (SM) of elementary particles and interactions. This relative theoretical simplicity makes charged pion decays a sensitive means for testing the underlying symmetries and the universality of weak fermion couplings, as well as for studying pion structure and chiral dynamics. Even after considerable recent improvements, experimental precision is lagging far behind that of the theoretical description for pion decays. We review the current state of experimental study of the pion electronic decay $\pi^+ \to e^+\nu_e(\gamma)$, or $\pi_{e2(\gamma)}$, where the $(\gamma)$ indicates inclusion and explicit treatment of radiative decay events. We briefly review the limits on non-SM processes arising from the present level of experimental precision in $\pi_{e2(\gamma)}$ decays. Focusing on the PEN experiment at the Paul Scherrer Institute (PSI), Switzerland, we examine the prospects for further improvement in the near term.Comment: 11 pages, 5 figures; paper presented at the XIII International Conference on Heavy Quarks and Leptons, 22-27 May 2016, Blacksburg, Virginia, US

Precise Measurement of the Pi+ -> Pi0 e+ nu Branching Ratio

Using a large acceptance calorimeter and a stopped pion beam we have made a precise measurement of the rare Pi+ -> Pi0 e+ Nu,(pi_beta) decay branching ratio. We have evaluated the branching ratio by normalizing the number of observed pi_beta decays to the number of observed Pi+ -> e+ Nu, (pi_{e2}) decays. We find the value of Gamma(Pi+ -> Pi0 e+ Nu)/Gamma(total) = [1.036 +/- 0.004(stat.) +/- 0.004(syst.) +/- 0.003(pi_{e2})] x 10^{-8}$, where the first uncertainty is statistical, the second systematic, and the third is the pi_{e2} branching ratio uncertainty. Our result agrees well with the Standard Model prediction.Comment: 4 pages, 5 figures, 1 table, revtex4; changed content; updated analysi

Design, Commissioning and Performance of the PIBETA Detector at PSI

We describe the design, construction and performance of the PIBETA detector built for the precise measurement of the branching ratio of pion beta decay, pi+ -> pi0 e+ nu, at the Paul Scherrer Institute. The central part of the detector is a 240-module spherical pure CsI calorimeter covering 3*pi sr solid angle. The calorimeter is supplemented with an active collimator/beam degrader system, an active segmented plastic target, a pair of low-mass cylindrical wire chambers and a 20-element cylindrical plastic scintillator hodoscope. The whole detector system is housed inside a temperature-controlled lead brick enclosure which in turn is lined with cosmic muon plastic veto counters. Commissioning and calibration data were taken during two three-month beam periods in 1999/2000 with pi+ stopping rates between 1.3*E3 pi+/s and 1.3*E6 pi+/s. We examine the timing, energy and angular detector resolution for photons, positrons and protons in the energy range of 5-150 MeV, as well as the response of the detector to cosmic muons. We illustrate the detector signatures for the assorted rare pion and muon decays and their associated backgrounds.Comment: 117 pages, 48 Postscript figures, 5 tables, Elsevier LaTeX, submitted to Nucl. Instrum. Meth.

Precise Measurement of pi+ -> e+ nu Branching Ratio

The PEN Collaboration is conducting a new measurement of the pi+ -> e+ nu branching ratio at the Paul Scherrer Institute, with the goal uncertainty of delta B/B(pie2)=5E-4 or lower. At present, the combined accuracy of all published pie2 decay measurements lags behind the theoretical calculation by a factor of 40. In this contribution we report on the PEN detector configuration and its performance during two development runs done in 2007 and 2008.Comment: pdflatex, 11 pages, 5 figures, to be published in "Progress in High-Energy Physics and Nuclear Safety", NATO Science for Peace Series: B - Physics and Biophysic

ProSAAS-Derived Peptides are Colocalized with Neuropeptide Y and Function as Neuropeptides in the Regulation of Food Intake

ProSAAS is the precursor of a number of peptides that have been proposed to function as neuropeptides. Because proSAAS mRNA is highly expressed in the arcuate nucleus of the hypothalamus, we examined the cellular localization of several proSAAS-derived peptides in the mouse hypothalamus and found that they generally colocalized with neuropeptide Y (NPY), but not α-melanocyte stimulating hormone. However, unlike proNPY mRNA, which is upregulated by food deprivation in the mediobasal hypothalamus, neither proSAAS mRNA nor proSAAS-derived peptides were significantly altered by 1–2 days of food deprivation in wild-type mice. Furthermore, while proSAAS mRNA levels in the mediobasal hypothalamus were significantly lower in Cpefat/fat mice as compared to wild-type littermates, proNPY mRNA levels in the mediobasal hypothalamus and in other subregions of the hypothalamus were not significantly different between wild-type and Cpefat/fat mice. Intracerebroventricular injections of antibodies to two proSAAS-derived peptides (big LEN and PEN) significantly reduced food intake in fasted mice, while injections of antibodies to two other proSAAS-derived peptides (little LEN and little SAAS) did not. Whole-cell patch clamp recordings of parvocellular neurons in the hypothalamic paraventricular nucleus, a target of arcuate NPY projections, showed that big LEN produced a rapid and reversible inhibition of synaptic glutamate release that was spike independent and abolished by blocking postsynaptic G protein activity, suggesting the involvement of a postsynaptic G protein-coupled receptor and the release of a retrograde synaptic messenger. Taken together with previous studies, these findings support a role for proSAAS-derived peptides such as big LEN as neuropeptides regulating food intake