9,128 research outputs found

    Introduction: Special issue on genetic research of alcohol use disorder in diverse racial/ethnic populations

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    This special issue of The American Journal on Addictions is an extension of a workshop held at the Research Society on Alcoholism (2015) highlighting several important issues related to studies of the genetic bases of alcohol use disorder among racially/ethnically diverse populations. While not exhaustive in their coverage, the papers in this special issue focus on three important topics: (1) the importance of considering the social and environmental context in genetic analyses; (2) social and cultural considerations for engaging diverse communities in genetic research; and (3) methodologies related to phenotype development for use with racially/ethnically diverse populations. A brief overview of each paper included in these three sections is presented. The issue concludes with additional considerations for genetic research with racially/ethnically diverse population groups along with a commentary. (Am J Addict 2017;26:422–423

    Topology Classes of Flat U(1) Bundles and Diffeomorphic Covariant Representations of the Heisenberg Algebra

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    The general construction of self-adjoint configuration space representations of the Heisenberg algebra over an arbitrary manifold is considered. All such inequivalent representations are parametrised in terms of the topology classes of flat U(1) bundles over the configuration space manifold. In the case of Riemannian manifolds, these representations are also manifestly diffeomorphic covariant. The general discussion, illustrated by some simple examples in non relativistic quantum mechanics, is of particular relevance to systems whose configuration space is parametrised by curvilinear coordinates or is not simply connected, which thus include for instance the modular spaces of theories of non abelian gauge fields and gravity.Comment: 22 pages, no figures, plain LaTeX file; changes only in details of affiliation and financial suppor

    Energy spectrum of graphene multilayers in a parallel magnetic field

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    We study the orbital effect of a strong magnetic field parallel to the layers on the energy spectrum of the Bernal-stacked graphene bilayer and multilayers, including graphite. We consider the minimal model with the electron tunneling between the nearest sites in the plane and out of the plane. Using the semiclassical analytical approximation and exact numerical diagonalization, we find that the energy spectrum consists of two domains. In the low- and high-energy domains, the semiclassical electron orbits are closed and open, so the spectra are discrete and continuous, correspondingly. The discrete energy levels are the analogs of the Landau levels for the parallel magnetic field. They can be detected experimentally using electron tunneling and optical spectroscopy. In both domains, the electron wave functions are localized on a finite number of graphene layers, so the results can be applied to graphene multilayers of a finite thickness.Comment: 11 pages, 13 figures. Added to v.2: Appendix A, Fig. 13, Refs. [18-23]. V.3: minor stylistic corrections from the published versio

    Pulsating Strings in Deformed Backgrounds

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    This is a brief summary on pulsating strings in beta deformed backgrounds found recently.Comment: 8 pages. Talk presented at Quantum Theory and Symmetries 7, Prague, August 7-13, 201

    Hyperon--anti-hyperon polarization asymmetry in relativistic heavy-ion collisions as an interplay between chiral and helical vortical effects

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    We argue that the enhancement in the spin polarization of anti-hyperons compared to the polarization of the hyperons in noncentral relativistic heavy-ion collisions arises as a result of an interplay between the chiral and helical vortical effects. The chiral vortical effect generates the axial current of quarks along the vorticity axis while the recently found helical vortical effect generates the helicity flow -- the projection of the quark's polarization vector onto its momentum -- along the same axis. For massless fermions, the helical charge corresponds to a difference in the contributions of particles and anti-particles to the axial charge. Assuming that the spin of light quarks transfers to the strange quarks via the vector kaon states ("the spin-vector dominance"), we are able to describe the ratio of the (anti)hyperon spin polarizations, obtained by the STAR group, without fitting parameters. We also argue that the helical vortical effect dominates over the chiral vortical effect and the chiral magnetic effect in the generation of the electric current.Comment: 9 pages, 3 figures; v2: discussions expanded, chiral magnetic effect and helical vortical effect are compare

    Perancangan Promosi O\u27jamur Sebagai Wujud Peduli Dengan Lingkungan Alam

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    O\u27jamur restoran merupakan restoran peduli bumi yang terletak di Jl. Bridjen Katamso 270 Waru, Sidoarjo. O\u27jamur restoran ingin agar visi dan misi restorannya yakni menjaga lingkungan alam dari makanan yang di konsumsi sehari-hari dapat di ketahui oleh anak muda. Dengan tujuan agar lebih memperhatikan komposisi makanan mereka dan mulai merubahnya dari sekarang. Untuk mewujudkan hal tersebut, melakukan sebuah promosi dengan cara membuat gerakkan yang mengajak anak muda untuk mengonsumsi jamur tiram putih sebagai salah satu bahan makanan yang bermanfaat baik bagi tubuh dan lingkungan alam. Melalui gerakkan tersebut, informasi untuk mengonsumsi jamur tiram putih sebagai salah satu makanan yang sehat untuk tubuh dan lingkungan dapat tersebar ke masyarakat khususnya kota Surabaya

    The thermodynamic limit for fractional exclusion statistics

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    I discuss Haldane's concept of generalised exclusion statistics (Phys. Rev. Lett. {\bf 67}, 937, 1991) and I show that it leads to inconsistencies in the calculation of the particle distribution that maximizes the partition function. These inconsistencies appear when mutual exclusion statistics is manifested between different subspecies of particles in the system. In order to eliminate these inconsistencies, I introduce new mutual exclusion statistics parameters, which are proportional to the dimension of the Hilbert sub-space on which they act. These new definitions lead to properly defined particle distributions and thermodynamic properties. In another paper (arXiv:0710.0728) I show that fractional exclusion statistics manifested in general systems with interaction have these, physically consistent, statistics parameters.Comment: 8 page

    Evidence of increased hypoxia signaling in fetal liver from maternal nutrient restriction in mice.

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    BACKGROUND: Intrauterine growth restriction (IUGR) is a pregnancy condition where fetal growth is reduced, and offspring from IUGR pregnancies are at increased risk for type II diabetes as adults. The liver is susceptible to fetal undernutrition experienced by IUGR infants and animal models of growth restriction. This study aimed to examine hepatic expression changes in a maternal nutrient restriction (MNR) mouse model of IUGR to understand fetal adaptations that influence adult metabolism. METHODS: Liver samples of male offspring from MNR (70% of ad libitum starting at E6.5) or control pregnancies were obtained at E18.5 and differential expression was assessed by RNAseq and western blots. RESULTS: Forty-nine differentially expressed (FDR \u3c 0.1) transcripts were enriched in hypoxia-inducible pathways including Fkbp5 (1.6-fold change), Ccng2 (1.5-fold change), Pfkfb3 (1.5-fold change), Kdm3a (1.2-fold change), Btg2 (1.6-fold change), Vhl (1.3-fold change), and Hif-3a (1.3-fold change) (FDR \u3c 0.1). Fkbp5, Pfkfb3, Kdm3a, and Hif-3a were confirmed by qPCR, but only HIF-2a (2.2-fold change, p = 0.002) and HIF-3a (1.3 p = 0.03) protein were significantly increased. CONCLUSION: Although a moderate impact, these data support evidence of fetal adaptation to reduced nutrients by increased hypoxia signaling in the liver

    High Energy Hadron-Nucleus Cross Sections and Their Extrapolation to Cosmic Ray Energies

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    Old models of the scattering of composite systems based on the Glauber model of multiple diffraction are applied to hadron-nucleus scattering. We obtain an excellent fit with only two free parameters to the highest energy hadron-nucleus data available. Because of the quality of the fit and the simplicity of the model it is argued that it should continue to be reliable up to the highest cosmic ray energies. Logarithmic extrapolations of proton-proton and proton-antiproton data are used to calculate the proton-air cross sections at very high energy. Finally, it is observed that if the exponential behavior of the proton-antiproton diffraction peak continues into the few TeV energy range it will violate partial wave unitarity. We propose a simple modification that will guarantee unitarity throughout the cosmic ray energy region.Comment: 8 pages, 9 postscript figures. This manuscript replaces a partial manuscript incorrectly submitte
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