20 research outputs found
Spinal Cord Stimulation Prevents Autonomic Dysreflexia in Individuals with Spinal Cord Injury:A Case Series
Photo- and thermoinduced ring opening reaction of 2[(1,3,3-trimethylindoline-2(1H)-yliden)propen-1-yl]-3,3-dimethylindolino[1,2-b]-oxazolidine in polymer films
Defective triggering of secondary peristalsis in patients with non-erosive reflux disease
The definitive version is available at www.blackwell-synergy.com Copyright © 2006 The Authors, Journal compilation © 2007 Journal of Gastroenterology and Hepatology Foundation and Blackwell Publishing Asia Pty LtdBackground and Aim: The pathophysiology of non-erosive reflux disease is poorly understood. Triggering of secondary peristalsis is impaired in patients with erosive esophagitis but data in patients with non-erosive reflux disease are lacking. The aim of this study was to evaluate the difference in esophageal motility between patients with non-erosive reflux disease and healthy subjects. Methods: Twenty patients with non-erosive reflux disease, with reflux symptoms occurring more than twice per week, and 20 healthy subjects of comparable age and sex underwent esophageal manometry. Primary peristalsis was tested with 10 swallows of a 5-mL water bolus. Secondary peristalsis was triggered by esophageal distention using a 20-mL air bolus, which was injected rapidly into the mid-esophagus. After 20 s, each stimulus was followed by a dry swallow to clear any residual air and then each stimulus was repeated five times. Results: Basal lower esophageal sphincter pressure, pressure wave amplitude in the upper, middle and lower esophagus, wave velocity and the rates of successful primary peristalsis were similar in non-erosive reflux disease patients and controls. The rate of triggering of secondary peristalsis in patients with non-erosive reflux disease (median 20%, interquartile range 0â40%) was significantly lower (P < 0.0001) than that in healthy subjects (90%, 70â100%). When secondary peristalsis occurred in patients with non-erosive reflux disease, however, there were no differences in the amplitude and velocity of secondary peristalsis between the groups. Conclusions: Triggering of secondary peristalsis is defective in non-erosive reflux disease. This could lead to prolongation of the contact time between refluxed gastric acid and esophageal mucosa thereby leading to symptoms.Katsuhiko Iwakiri, Yoshinori Hayashi, Makoto Kotoyori, Yuriko Tanaka, Noriyuki Kawami, Hirohito Sano, Kaiyo Takubo, Choitsu Sakamoto and Richard H Hollowa
P032 Preclinical study of a novel immunotherapy for renal cell carcinoma: Combination of long and short peptides
A new heterotrophic dinoflagellate from the North-eastern Pacific, Protoperidinium fukuyoi: cystâtheca relationship, phylogeny, distribution and ecology
The cyst-theca relationship of Protoperidinium fukuyoi n. sp. (Dinoflagellata, Protoperidiniaceae) is established by incubating resting cysts from estuarine sediments off southern Vancouver Island, British Columbia, Canada, and San Pedro Harbor, California, USA. The cysts have a brown-coloured wall, and are characterized by a saphopylic archeopyle comprising three apical plates, the apical pore plate and canal plate; and acuminate processes typically arranged in linear clusters. We elucidate the phylogenetic relationship of P. fukuyoi through large and small subunit (LSU and SSU) rDNA sequences, and also report the SSU of the cyst-defined species Islandinium minutum (Harland & Reid) Head etal. 2001. Molecular phylogenetic analysis by SSU rDNA shows that both species are closely related to Protoperidinium americanum (Gran & Braarud 1935) Balech 1974. Large subunit rDNA phylogeny also supports a close relationship between P. fukuyoi and P. americanum. Three subgroups in total are further characterized within the Monovela group. The cyst of P. fukuyoi shows a wide geographical range along the coastal tropical to temperate areas of the North-east Pacific, its distribution reflecting optimal summer sea-surface temperatures of similar to 14-18 degrees C and salinities of 22-34psu
A New Heterotrophic Dinoflagellate from the North-eastern Pacific, Protoperidinium fukuyoi
The 54,56Fe(d,n)55,57Co Reactions at Ed=25MeV and Single-Particle Energies of Nuclei from A = 48 to 60
The 54,56Fe(d,n)55,57Co Reactions at Ed=25MeV and Single-Particle Energies of Nuclei from A = 48 to 60
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