ENDOCERVICAL GLANDULAR INVOLVEMENT, MULTICENTRICITY AND EXTENT OF THE DISEASE ARE FEATURES OF HIGH GRADE CERVICAL INTRAEPITHELIAL NEOPLASIA

WOS: 000330379501377

Isolated tubal torsion in pregnancy - a rare case

WOS: 000294753300022PubMed ID: 21995163Isolated fallopian tube torsion is an uncommon cause of acute abdomen in pregnancy. Patients present with lower quadrant abdominal pain, and some have nausea and vomiting. There is no pathognomic diagnostic sign, so most patients are operated when it is too late to save the tube by detorsion alone. Here we present a case of isolated tubal torsion in a term pregnancy managed by salpingectomy and cesarean section simultaneously. As far as we know this will be the 20th case of reported isolated tubal torsion in pregnancy

Retinol-binding protein 4, as a negative acute-phase reactant in polycystic ovary syndrome

WOS: 000346880800006PubMed ID: 25371056Aim. The aim of our study was to compare serum levels of RBP4 in women with PCOS to the control group and to understand the relationship among RBP4 and biochemical and hormonal parameters related to disease process, especially gonadal steroids and markers of inflammation., Methods. Twenty-eight women with PCOS (18 normal weight and 10 obese) and 27 normally menstruating healthy women (20 normal weight and 7 obese) were included. Results. Women with PCOS had higher RBP4 concentrations. RBP4 levels correlated negatively with LDL, hsCRP and LH in women with PCOS and positively with BMI in the control group. When obese PCOS were compared to normal weight PCOS, increased CRP levels correlated negatively with RBP4 only in the normal weight PCOS group (normal PCOS r=-0.465, P=0.042; obese PCOS r=-0.505, P=0.137). Regression analysis of the effects of CRP and BMI on RBP4 levels revealed a statistically significant relationship between CRP and RBP4 independent of BMI. Conclusion. Serum RBP4 levels increased in women with PCOS and correlated negatively with CRP, LH and LDL. RBP4 probably acts as a negative acute phase reactant in normal weight PCOS. It cannot be used as a marker of chronic low grade inflammation in women with PCOS

Squamous cell carcinoma developing in a huge dermoid cyst of the ovary in an 80-year-old woman - case report

WOS: 000244241100015PubMed ID: 17375712A case of an 80-year-old patient with squamous cell carcinoma originating from a huge septated dermoid cyst of the right ovary is reported. There were bilateral dermoids in the patient. The tumor sizes were 30 x 40 x 20 cm and 4 x 3 x 5 cm in the right and left ovary, respectively, confirmed by ultrasound and computed tomography. Squamous cell carcinoma arose in the solid part of a huge dermoid cyst of the left ovary. Total abdominal hysterectomy and bilateral salpingo-oophorectomy, omentectomy and appendectomy were performed. The tumor was confined to the right ovary. The patient was categorized as FIGO Stage IA. She recovered uneventfully and there was no evidence of recurrence in the early-stage case during one year of follow-up. The clinical and pathological features, treatment modalities and prognosis of squamous cell carcinoma are described

A SHORT RIB POLYDACTYLY SYNDROME OVERLAPPING BOTH LETHAL AND NONLETHAL TYPES

WOS: 000306574200012PubMed ID: 22876582A short rib polydactyly syndrome overlapping both lethal and nonlethal types: Short rib polydactyly syndrome (SRPS) type II is a rare, autosomal recessively inherited, lethal skeletal dysplasia characterized by polydactyly, short limbs, short and horizontal ribs, a short ovoid tibia and major organ anomalies. We report a patient with a fetus with SRPS type II that presented at the 19th week of pregnancy for amniocentesis because of maternal age. During ultrasound pre-axial synpolydacytly, a short and ovoid tibia, nuchal edema, vertebral irregularities, hypoplastic thorax with short ribs and talipes were detected. All of the extremities were under the 5th percentile. Thorax-abdomen ratio was 0,56. The family was counselled for a diagnosis of lethal SRPS. After termination of pregnancy, radiological and histopathological examination allowed us to reach the diagnosis of Majewski syndrome (SRPS type II). SRPSs are a continuous spectrum of both lethal and nonlethal forms. Prenatal diagnosis and termination depending on ultrasound findings should be done very precociously considering different phenotypic expressions, even in families previously affected by a lethal SRPS

Bilateral vulvar mass mimicking Bartholin's gland abscess in the postpartum period: Klippel-Trenaunay Syndrome

WOS: 000337902500022PubMed ID: 24766189