Kikuchi-Fujimoto disease presenting as pyrexia of unknown origin

Background: Kikuchi-Fujimoto disease, a benign self-limited lymphadenopathy is an uncommon cause of pyrexia of unknown origin (PUO). Methods: We retrospectively studied the case-records of 13 patients presenting with PUO who were diagnosed to have Kikuchi-Fujimoto disease on peripheral lymph node excision biopsy and report the salient clinical manifestations and histopathological findings in them. All of them received symptomatic treatment. Results: Their median age was 28 [interquartile range (IQR) 18.5-38.0] years. Women (11/13, 84.6%) were more frequently affected. All of them were human immunodeficiency virus (HIV) seronegative. Prior to presenting to us, two were being treated for lymph node tuberculosis with DOTS. Cervical lymph nodes were predominantly involved, the distribution being: right cervical (n=10, 76.9%); left cervical (n=4); and bilateral cervical (n=2). Axillary and generalized lymphadenopathy were rare being seen in 2 and 1 patient respectively. The median (IQR) erythrocyte sedimentation rate (n=11) was 53 (35-89) mm at the end of first hour. Salient histopathological features were paracortical patchy zones of eosinophilic fibrinoid necrosis with karyorrhectic debris, large numbers of histiocytes, including histiocytes with peripherally placed “crescentic” nuclei. Spontaneous regression of fever and lymphadenopathy was observed over a median (IQR) period of 8 (6.75-10.25) months in all of them. Conclusions: Kikuchi-Fujimoto disease is a rare but important cause of PUO presenting with peripheral lymphadenopathy. Women are most often affected and cervical lymph nodes are the most frequently involved site. Clinical suspicion and thoughtful collaboration between clinicians and pathologists are essential for accurate diagnosis, and to minimize unnecessary investigations and inappropriate aggressive treatment

Effect of Structured Teaching Programme on Neonatal Resuscitation among the Staff Nurses of Selected Hospitals at Bhopal, Madhya Pradesh, India

The present study was conducted to assess the effectiveness of structured teaching programme on neonatal resuscitation among the staff nurses. An experimental design was chosen with pre-test and post-test of experimental and control group. The sample size was 60 registered staff nurses divided into two groups as 30 in experimental and 30 in control group. The tools used for conducting the study included demographic variables, self-structured questioner to assess knowledge of experimental and control group. The experimental group was given structured teaching programme and the control group was used for comparison only. The data were analyzed with the help of descriptive and inferential statistics. The study clearly shows that there was a significant gain in knowledge of staff nurses in experimental group with structured teaching programme which emphasizes neonatal resuscitation by the staff nurses. Therefore, the staff nurses can be benefited with structured teaching programme to improve knowledge on neonatal resuscitation

Risk analaysis of ethanol blending fuel in refinery industry using event tree analysis and Topsis method

Chemicals have always posed risks including fire, explosion, and the release of harmful substances in process industries like the Petroleum Industry. The occurrence of such catastrophes has a significant impact on the resources for finances and daily living. In this research paper, the major safety-related causes and effects are identified through event tree analysis based on accidents and incidents while using ethanol as fuel. For this purpose, the accident and incident data collected so far while using ethanol in the fuel industry, detailed information about ethanol, and even tree analysis. The event tree analysis (ETA) and Technique for Order Preference by Similarity to Ideal Solution (TOPSIS) analysis method is utilized to Identifying an initiating event of interest of accident. The event tree\u27s structure also aids the analyst in identifying the locations where additional protocols or safety measures are required to mitigate accidents or lower their frequency

What controls seasonal evolution of sea surface temperature in the Bay of Bengal? Mixed layer heat budget analysis using moored buoy observations along 90°E

Author Posting. © The Oceanography Society, 2016. This article is posted here by permission of The Oceanography Society for personal use, not for redistribution. The definitive version was published in Oceanography 29, no. 2 (2016): 202–213, doi:10.5670/oceanog.2016.52.Continuous time-series measurements of near surface meteorological and ocean variables obtained from Research Moored Array for African-Asian-Australian Monsoon Analysis and Prediction (RAMA) moorings at 15°N, 90°E; 12°N, 90°E; and 8°N, 90°E and an Ocean Moored buoy Network for Northern Indian Ocean (OMNI) mooring at 18°N, 90°E are used to improve understanding of air-sea interaction processes and mixed layer (ML) temperature variability in the Bay of Bengal (BoB) at seasonal time scales. Consistent with earlier studies, this analysis reveals that net surface heat flux primarily controls the ML heat balance. The penetrative component of shortwave radiation plays a crucial role in the ML heat budget in the BoB, especially during the spring warming phase when the ML is thin. During winter and summer, vertical processes contribute significantly to the ML heat budget. During winter, the presence of a strong barrier layer and a temperature inversion (warmer water below the ML) leads to warming of the ML by entrainment of warm subsurface water into the ML. During summer, the barrier layer is relatively weak, and the ML is warmer than the underlying water (i.e., no temperature inversion); hence, the entrainment cools the mixed layer. The contribution of horizontal advection to the ML heat budget is greatest during winter when it serves to warm the upper ocean. In general, the residual term in the ML heat budget equation is quite large during the ML cooling phase compared to the warming phase when the contribution from vertical heat flux is small.WHOI buoy deployment was supported by the US Office of Naval Research (grant no. N00014- 13-10453)

Ab initio molecular dynamics using density based energy functionals: application to ground state geometries of some small clusters

The ground state geometries of some small clusters have been obtained via ab initio molecular dynamical simulations by employing density based energy functionals. The approximate kinetic energy functionals that have been employed are the standard Thomas-Fermi $(T_{TF})$ along with the Weizsacker correction $T_W$ and a combination $F(N_e)T_{TF} + T_W$. It is shown that the functional involving $F(N_e)$ gives superior charge densities and bondlengths over the standard functional. Apart from dimers and trimers of Na, Mg, Al, Li, Si, equilibrium geometries for $Li_nAl, n=1,8$ and $Al_{13}$ clusters have also been reported. For all the clusters investigated, the method yields the ground state geometries with the correct symmetries with bondlengths within 5\% when compared with the corresponding results obtained via full orbital based Kohn-Sham method. The method is fast and a promising one to study the ground state geometries of large clusters.Comment: 15 pages, 3 PS figure

Scaling of hadronic transverse momenta in a hydrodynamic treatment of relativistic heavy ion collisions

The transverse momenta of hadrons in central nucleus-nucleus collisions are evaluated in a boost invariant hydrodynamics with transverse expansion. Quark gluon plasma is assumed to be formed in the initial state which expands and cools via a first order phase transition to a rich hadronic matter and ultimately undergoes a freeze-out. The average transverse momentum of pions, kaons, and protons is estimated for a wide range of multiplicity densities and transverse sizes of the system. For a given system it is found to scale with the square-root of the particle rapidity density per unit transverse area, and consistent with the corresponding values seen in $p\overline{p}$ experiments at 1800 GeV, suggesting a universal behaviour. The average transverse momentum shows only an approximate scaling with multiplicity density per nucleon which is at variance with the $p\overline{p}$ data.Comment: 6 pages including 9 figure

A Clinical Cross Sectional study on Palmoplantar Dermatoses

BACKGROUND: Dermatoses of palms and soles are common in daily practice. They limit the day to day activities of the patients. Often there will be difficulties to differentiate, diagnose and treat these conditions. Hence thorough knowledge about diseases affecting palms and soles is required. AIM OF THE STUDY: To study the clinical features and frequency of involvement of various palmoplantar dermatoses and their epidemiological aspects like age, sex distribution and occupation. MATERIALS AND METHODS: 200 patients with diseases involving palms, soles or both were selected from OPD of Dermatology, Coimbatore Medical College Hospital, for a period of one year. In every patient, details like name, age, sex, occupation and marital status were noted. A detailed history of symptoms and their duration were recorded. A complete general and dermatological examination were carried out in all the patients. For scaly lesions, microscopic examination of scrapings in 10 percentage of KOH was done, in case of pustular lesions Gram Staining was done and for selected cases skin biopsy was taken. RESULTS: A total of 200 patients were enrolled, among which 53.46% were males. The most common age group affected was 17-40 years. Seasonal variation was reported in 45.5% of patients. The most common symptom was pruritus. Eczema was the most common palmoplantar dermatoses, followed by fungal infections and psoriasis. Palms were the most common site involved. CONCLUSION: Most of the studies in the palmoplantar dermatoses were focused on the specific diseases, this study highlights the need for comprehensive studies in palmoplantar dermatoses

RANSPLANTING DATES AND NITROGEN LEVELS INFLUENCES ON GROWTH, YIELD ATTRIBUTES, AND YIELD OF SUMMER PEARL MILLET

The experiment was taken with three dates of transplanting viz, Normal drilling at RSD (T1), first transplanting (Transplanting on RSD, T2) and second transplanting (Transplanting 25 days after RSD, T3) and four levels of nitrogen viz., 75% RDN (N1), 75% RDN + Azospirillum (N2), 100% RDN (N3), and 125% RDN (N4). Treatment T1 recorded significantly higher plant height (178.69 cm) length of earhead (21.79 cm), girth of earhead (9.71 cm), test weight (9.01 g), grain yield (35.90 kg ha-1) and straw yield (92.11 kg ha-1), and found statistically at par with treatment T2. Among nitrogen levels Significantly higher length of earhead (22.25 cm), girth of earhead (9.79 cm), test weight (9.10 g), grain yield (37.93 kg ha-1) and straw yield (94.45 kg ha-1) were recorded under treatment N4 but in case of length of earhead and grain yield, treatment N4 did not differ significantly with N3. Hence, summer pearlmillet crop should be sown by normal drilling or transplanting on RSD with 100% RDN

Impact of health education on unmet needs of contraception in urban slums of Chandigarh, India

Background: Unmet need points to gap between some women reproductive intention and their contraceptive behavior. Unmet need for contraception is mainly attributed to lack of information, negative attitude, fear of adverse effects and social influences. The objective of this study was to investigate awareness and practice of contraceptive usage. And to estimate unmet need of contraception in the studied population and to identify the factors associated with it, and to evaluate impact of health education on unmet needs of contraception.Methods: A community-based longitudinal study was conducted in four randomly selected urban slum areas (colonies) of Chandigarh, India. A systematic two-stage random sample design was adopted.Results: Overall contraceptive awareness rates among women and men were increased from 84.1% to 96.3% and from 82.2% to 95.5% in post-interventional survey as compared to baseline survey. Contraceptive prevalence rates were found to be 57.3% and 65.5% respectively in pre interventional and post interventional surveys, against contraceptive awareness rates of 81.7% and 95.5% respectively, resulting in gaps between knowledge and practice to be unmet needs of contraception to the extents of 24.4% and 30.0% respectively in the two surveys.Conclusions: There is an urgent need of adopting some population specific integral strategies for changing social norms and attitudes of couples regarding reproductive issues, increase in contraceptives awareness as well as practice for reductions in unmet needs of contraception and unwanted/unplanned pregnancies