53 research outputs found
A note on the (h,q)-Zeta type function with weight alpha
The objective of this paper is to derive symmetric property of (h,q)-Zeta
function with weight alpha. By using this property, we give some interesting
identities for (h,q)-Genocchi polynomials with weight alpha. As a result, our
applications possess a number of interesting property which we state in this
paper.Comment: 7 page
A note on q-Bernstein polynomials
In this paper we constructed new q-extension of Bernstein polynomials. Fron
those q-Berstein polynomials, we give some interesting properties and we
investigate some applications related this q-Bernstein polynomials.Comment: 13 page
New identities involving q-Euler polynomials of higher order
In this paper we give new identities involving q-Euler polynomials of higher
order.Comment: 11 page
Identities involving values of Bernstein, q-Bernoulli and q-Euler polynomials
In this paper we give some relation involving values of q-Bernoulli, q-Euler
and Bernstein polynomials. From these relations, we obtain some interesting
identities on the q-Bernoulli, q-Euler and Bernstein polynomials.Comment: 12 page
Cellular differentiation determines the expression of the hypoxia-inducible protein NDRG1 in pancreatic cancer
N-myc downstream-regulated gene-1 (NDRG1) is a recently described hypoxia-inducible protein that is upregulated in various human cancers. Pancreatic ductal adenocarcinoma, called pancreatic cancer, is a highly aggressive cancer that is characterised by its avascular structure, which results in a severe hypoxic environment. In this study, we investigated whether NDRG1 is upregulated in these tumours, thus providing a novel marker for malignant cells in the pancreas. By immunohistochemistry, we observed that NDRG1 was highly expressed in well-differentiated cells of pancreatic cancer, whereas the poorly differentiated tumour cells were negative. In addition, hyperplastic islets and ducts of nonquiescent pancreatic tissue were positive. To further explore its selective expression in tumours, two well-established pancreatic cancer cell lines of unequal differentiation status were exposed to 2% oxygen. NDRG1 mRNA and protein were upregulated by hypoxia in the moderately differentiated Capan-1 cells; however, its levels remained unchanged in the poorly differentiated Panc-1 cell line. Taken together, our data suggest that NDRG1 will not serve as a reliable marker of tumour cells in the pancreas, but may serve as a marker of differentiation. Furthermore, we present the novel finding that cellular differentiation may be an important factor that determines the hypoxia-induced regulation of NDRG1
AKT inhibitor suppresses hyperthermia-induced Ndrg2 phosphorylation in gastric cancer cells
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