Oral Rehabilitation of Trauma - a Clinical Report

Ozljede glave i vrata od nezgoda u životu na selu nisu česte (4% prema Zachariades na uzorku od 6000 pacijenata). Jedan od najčešćih uzroka među tim nezgodama jesu u vezi s poljoprivrednim strojevima, osobito otvorenima. To su vozila koja ne razvijaju velike brzine , ali upotreba zaštitnih sredstva je rijetka. U slučajevima kada vozač ispaden iz vozila ili se ono prevrne nastaju velike ozljede lica koje su u mnogočemu drugačije od ozljeda u ostalim prometnim nesrećama.. Prikazan je slučaj liječenja pacijenta na Klinici za maksilofacijalnu kirurgiju i Kliničkom zavodu za stomatološku protetiku Kliničke bolnice Dubrava. Pacijent u dobi od 32 godine starosti preživio je prevrtanje traktora, no nagnječena mu je desna strana srednjeg lica. Nakon nekoliko uspješnih rekonstruktivnih zahvata započeta je oralna rehabilitacija. Narav ozljede te preostali broj zuba odredili su način odgovarajuće oralne rahabilitacije.Head and neck injuries caused by accidents associated with rural life are not frequent (4% according to Zachariades on a survey of more than 6000 patients). One of the most frequent among those accidents are agricultural vehicle accidents, especially open vehicles. These vehicles do not develop high speed and helmets are seldom required. Therefore in cases of falling out of a vehicle or turning of the vehicle very extensive facial injury occurs which is quite different from other road traffic accident injuries. A report of the treatment and outcome of a case tretaed at the Clinic for Maxillofacial surgery and Department of Prosthodontics, University Hospital Dubrava is presented. A 32 year-old man survived accident in with the tractor oveerturned During the accident the right side of his midface was smashed. Clinical examination and x-rays revealed a defect of the right cheek including the complete zygomatic bone with the floor of the orbit and lateral upper part of the maxilla including molar teeth with adjacent bone and soft tissue. The skin of the cheek was missing and buccal lining was severely reduced. After initial examination and stabilization, immediate surgery was performed. The patient was satisfied with the appearance, after several major reconstructive procedures (three distant flaps and two local flaps) and oral rehabilitation started. The nature of the injury and the position of the left teeth started the procedure of the oral rehabilitation. The choice was a metal alloy upper partial denture with telescopic crown, and fixed frontal down bridge with attachment and lower partial denture from metal alloy

EFFICACY OF 15% FORMIC ACID ON VARROA MITES IN DIFFERENT FORMS OF APPLICATION

Varroa destructor je pčelinji nametnik odgovoran za smanjenu proizvodnju meda i legla i veću smrtnost pčela tokom zime. Zbog sve veće rezistentnosti nametnika na akaricide i njihovih rezidua u pčelinjim proizvodima sve se više upotrebljavaju alternativne metode i sredstva u liječenju varoe. Jedna od tih metoda je i tretiranje mravljom kiselinom. Mravlja kiselina djeluje na nametnika u poklopljenom leglu i ne ostavlja rezidue u pčelinjim proizvodima. Koncentrirana mravlja kiselina (60-85%) je vrlo efikasna, ali pri povišenim temperaturama zraka negativno utječe na pčele. U poslijednje se vrijeme u liječenju varooze, osim koncentrirane, preporuča i upotreba razrijeđene, 15%-tne, mravlje kiseline. Razrijeđena mravlja kiselina smanjuje reakciju pčela na liječenje, a povećanje vanjske temperature i različiti načini primjene pozitivno utječu na njenu djelotvornost (65 – 95%).Varroa destructor is a parasitic mite of the honeybee, Apis mellifera, responsible for reduced honey and brood production, higher bee mortality in winter. Because the resistance to the acaricides and they residues to bee products, alternative products and methods have been used against Varroa. One of this methods is treatment with formic acid. Formic acid induce to Varroa mite in brood and do not leave any residues in products. Concentric formic acid (60-85%) is very effective, but at higher air temperature, it has influence on bee. In the last few years, except concentric formic acid, 15 % formic acid was recommended as control of varroosis. Diluted formic acid (15%) reduced the bee response to treatment. In treatment with 15% formic acid, higher air temperature and different forms of application have positive influence to they function (65 – 95%)

Developmental diet defines metabolic traits in larvae and adult Drosophila

The influence of the developmental nutrition on adult metabolism and overall performance becomes a hot topic of modern evolutionary biology. We used fruit fly Drosophila melanogaster as a model and experimental nutrition media composed of different sucrose content (S) and dry yeast content (Y): 0S:2Y, 20S:2Y or 0S:5Y, 20S:5Y to show that the developmental nutrition conditions define metabolism in larvae and adults. The level of glucose, glycogen, triglycerids and total lipids in the larvae and flies body were measured with the diagnostic assay kits. We found that individuals developed on either low-yeast or high-sugar diet showed delayed developmental rate. When kept on the diets with high sucrose content the larvae and adult flies had lower weight and higher amount of lipids as energy reserves. Restriction of dry yeast content in the diet of larvae led to a decrease in glycogen storage and protein levels in larvae and adult flies. The results obtained indicate that the metabolic traits revealed in adult flies are the result of nutrition during development and may be associated with mechanisms of organisms adaptation to the developmental nutritional conditions

The Rise of Three Rs Centres and Platforms in Europe*

Public awareness and discussion about animal experiments and replacement methods has greatly increased in recent years. The term 'the Three Rs', which stands for the Replacement, Reduction and Refinement of animal experiments, is inseparably linked in this context. A common goal within the Three Rs scientific community is to develop predictive non-animal models and to better integrate all available data from in vitro, in silico and omics technologies into regulatory decision-making processes regarding, for example, the toxicity of chemicals, drugs or food ingredients. In addition, it is a general concern to implement (human) non-animal methods in basic research. Toward these efforts, there has been an ever-increasing number of Three Rs centres and platforms established over recent years - not only to develop novel methods, but also to disseminate knowledge and help to implement the Three Rs principles in policies and education. The adoption of Directive 2010/63/EU on the protection of animals used for scientific purposes gave a strong impetus to the creation of Three Rs initiatives, in the form of centres and platforms. As the first of a series of papers, this article gives an overview of the European Three Rs centres and platforms, and their historical development. The subsequent articles, to be published over the course of ATLA's 50th Anniversary year, will summarise the current focus and tasks as well as the future and the plans of the Three Rs centres and platforms. The Three Rs centres and platforms are very important points of contact and play an immense role in their respective countries as 'on the ground' facilitators of Directive 2010/63/EU. They are also invaluable for the widespread dissemination of information and for promoting implementation of the Three Rs in general

The Current Status and Work of Three Rs Centres and Platforms in Europe*

The adoption of Directive 2010/63/EU on the protection of animals used for scientific purposes has given a major push to the formation of Three Rs initiatives in the form of centres and platforms. These centres and platforms are dedicated to the so-called Three Rs, which are the Replacement, Reduction and Refinement of animal use in experiments. ATLA's 50th Anniversary year has seen the publication of two articles on European Three Rs centres and platforms. The first of these was about the progressive rise in their numbers and about their founding history; this second part focuses on their current status and activities. This article takes a closer look at their financial and organisational structures, describes their Three Rs focus and core activities (dissemination, education, implementation, scientific quality/translatability, ethics), and presents their areas of responsibility and projects in detail. This overview of the work and diverse structures of the Three Rs centres and platforms is not only intended to bring them closer to the reader, but also to provide role models and show examples of how such Three Rs centres and platforms could be made sustainable. The Three Rs centres and platforms are very important focal points and play an immense role as facilitators of Directive 2010/63/EU 'on the ground' in their respective countries. They are also invaluable for the wide dissemination of information and for promoting the implementation of the Three Rs in general

The Global Burden of Snakebite: A Literature Analysis and Modelling Based on Regional Estimates of Envenoming and Deaths

Janaka de Silva and colleagues estimate that globally at least 421,000 envenomings and 20,000 deaths occur each year due to snakebite

The politics of performance: transnationalism and its limits in former Yugoslav popular music, 1999–2004

This paper examines transnational relations between the Yugoslav successor states from the point of view of popular music, and demonstrates how transnational musical figures (such as Djordje Balaševi?, Mom?ilo Bajagi?-Bajaga and Ceca Ražnatovi?) are interpreted as symbolic reference points in national ethnopolitical discourse in the process of identity construction. Another symbolic function is served by Serbian turbofolk artists, who in Croatia serve as a cultural resource to distance oneself from a musical genre associated by many urban Croats with the ruralization (and Herzegovinization) of Croatian city space. In addition, value judgements associated with both Serbian and Croatian newly composed folk music provide an insight into the transnational negotiation of conflicting identities in the ex-Yugoslav context. Ultimately the paper shows how the ethnonational boundaries established by nationalizing ideologies created separate cultural spaces which themselves have been transnationalized after Yugoslavia's disintegration

About sensititvity: salmonella biofi lms’ resistance to disinfectants action

Salmonella biofi lms’ resistance to the action of the disinfectants was studied. It was founded that Salmonella biofi lms, which were formed on the hard carriers during 24 hours of incubation, demanded 32-fold increase of the minimal bactericide concentration of the disinfectant with quaternary ammonium compound