8 research outputs found
CAT and SOD activity.
<p>Erythrocytes were pretreated with resveratrol (RSV, 100 μM and 1000 μM) for 1 h at 37°C and incubated for 30 min with DDS-NHOH (2.5 μg/ml) or T-BHP (200 μM). Results are expressed as mean ± S.E.M. *P < 0.05 compared to methanol group.</p
Proposal for a possible action mechanism of resveratrol (RSV) in inhibiting methemoglobin formation and DNA damage induced by DDS hydroxylamine (DDS-NHOH) <i>in vitro</i> model.
<p>Proposal for a possible action mechanism of resveratrol (RSV) in inhibiting methemoglobin formation and DNA damage induced by DDS hydroxylamine (DDS-NHOH) <i>in vitro</i> model.</p
Comparative effect of post-treatment with resveratrol (RSV) or methylene blue (MET) on methemoglobin formation induced by DDS-NHOH.
<p>Erythrocytes were incubated for 1 h with DDS-NHOH (2.5 μg/mL), then these cells were incubated with RSV (100μM) for 1 h or MET(40 nM). Data are reported as mean ± S.E.M. *P < 0.05 compared to methanol group. <sup>#</sup>P < 0.05 compared to DDS-NHOH group.</p
Redox mechanism.
<p>Ionization potential and stabilization energy of dapsone hydroxylamine (DDS-NHOH), resveratrol (RSV), and methylene blue (MET) on antioxidant and methemoglobinemia reversion.</p
Effect of treatment with resveratrol on DNA damage induced by DDS-NHOH.
<p>Tail Length (μm—<b>A</b>), DNA in tail (%—<b>B</b>) Tail Moment (TM—<b>C</b>) and Olive Moment (OM—<b>D</b>) were used as a marker of DNA damage in lymphocyte using Comet assay. As positive control was used H<sub>2</sub>O<sub>2</sub> (200 μM). All values are depicted as mean ± S.E.M.</p
Effect of the DDS-NHOH on methemoglobin formation in human erythrocytes.
<p>Erythrocytes were incubated with different concentrations of DDS-NHOH (2.5; 5.0 and 7.5 μg/mL) for 1 h at 37°C. Data are reported as means ± S.E.M from three independent experiments done in triplicate. *P < 0.05 compared to methanol group.</p
HOMO surface.
<p>Structure for HOMO of the dapsone hydroxylamine (DDS-NHOH), resveratrol (RSV), and methylene blue (MET). All nodal patterns related to individual group contributions are presented by blue or yellow for negative or positive wave function, respectively.</p
Effect of the pretreatment with different concentration of resveratrol (RSV) on methemoglobin formation induced by DDS-NHOH.
<p>Erythrocytes were pretreated with different concentrations of RSV(10, 100, 200 and 1000 μM) for 1 h at 37°C, then these cells were incubated with different concentrations of DDS-NHOH (2.5; 5.0 and 7.5 μg/mL) for 1 h at 37°C. Data are reported as means ± S.E.M from three independent experiments done in triplicate. <sup><b>#</b></sup>P < 0.05 compared to DDS-NHOH group.</p