PROSPECTS FOR USE RARE EARTH METAL OXIDES NANOPARTICLES IN BIOLOGY AND MEDICINE

Rare earth metal dioxide nanoparticles are promising as analogs of biological enzymes. The main research problem is the high dependence on both the structure of nanoparticles and the reaction conditions. Research is aimed at identifying the optimal structure of nanoparticles and environment

Optical and luminescent properties of ceria nanoparticles produced by gas phase method

The study on luminescent and optical properties of ceria nanoparticles allow one to indirectly assess the defectiveness of the material crystal lattice. The decomposition of the luminescence spectrum in the Gaussian bands shows the presence of Ce3+ ions in the CeO2 crystal lattice, as well as optical active centers, probably associated with oxygen vacancies. These characteristics permit us to estimate the relative amount of Ce3+ ions in the crystal lattice and could be considered as an important prerequisite for the use of nanoparticles as redox agents in industry and medicine. © 2020 IOP Publishing Ltd.Russian Science Foundation, RSF: 18-72-00041The work was supported by Russian Science Foundation project № 18-72-00041

Modifying the surface of cerium oxide nanopowders produced by physical method

Cerium oxide nanoparticles present an interesting material for different industrial applications in biotechnology and medicine. The CeO2 nanopowder was produced by the method of pulsed electron evaporation of ceramic oxide targets with condensation of the vapors in a low pressure gas. The modification of nanoparticle surface was made with sodium citrate and N-phosphonomethylaminodiacetic acid. The stable aqueous suspensions of CeO2 nanoparticles could not be obtained in the work. This is probably due to the high hydrophobic properties of the nanoparticle surface. The cerium oxide nanoparticles with different stabilizers exhibit luminescence properties. © 2019 Author(s)

Gd2O3, SiO2-Gd2O3 and SiO2-MnO2 nanoparticles as potential MRI contrast agents

Gd2O3, SiO2-Gd2O3 and SiO2-MnO2 nanoparticles were produced by the method of pulsed electron evaporation of oxide targets with condensation of the vapors in a vacuum. These materials are considered as probable contrast agents for magnetic resonance imaging (MRI). The Gd2O3 nanoparticles exhibit a rather high r1 and r2 relaxivities. These results point to the potential of using nanocrystals for MRI diagnosis. The mesoporous nanostructures SiO2-Gd2O3 and SiO2-MnO2 could be considered as multimodal theranostic agents. © 2020 IOP Publishing Ltd

Modifying the Surface of Cerium Oxide Nanopowders Produced by Physical Method

The work was supported by Russian Science Foundation project № 18-72-00041. The authors are grateful to A. N. Kiryakov (Ural Federal University) for assistance in luminescence measurements

REDUCE THE TOXICITY OF ZINC OXIDE BY MODIFYING THE APPLIED SURFACE OF SILICON OXIDE

Despite the widespread use of zinc oxide nanoparticles in the chemical industry, electronics, medicine and cosmetology, the compound has high toxicity to humans and the environment. One way to reduce toxicity is the application layer of SiO2 on nanoparticles ZnO.SiO2/ZnO nanoparticles moderated the toxicity of ZnO by restricting free radical formation and the release of zinc ions, and decreasing surface contact with cells

Effect of Cerium Dioxide Nanoparticles Doping with Rare Earth Metal Ions on the Biocatalytic Activity

Nanocrystalline ceria takes active part in redox processes. Doping with rare earth ions modifies biocatalytic activity due to the change of the surface oxidation level and the number of oxygen vacancies. The results of a study of catalytic activity of pure and doped CeO2 nanoparticles are presented

STABILIZATION OF NANOPARTICLES IN AQUEOUS SUSPENSION FOR BIOLOGICAL APPLICATION

The using of nanoparticles for biological application requires the preparation of stable aqueous suspensions. The main principle is the encapsulation of nanoparticles with a layer of substance that will prevent the formation of nanoparticle agglomerates. As stabilizers generally chosen substances capable to adsorb onto the surface of nanoparticles or complex organic compounds that act as frame members which lie between the nanoparticles. One important feature of the stabilizer is its toxicity towards biological objects

OBTAINING AND STUDYING THE OPTICAL PROPERTIES OF FILMS BASED ON CERIUM OXIDE NANOPARTICLES

Composites films based on cerium dioxide nanoparticles were obtained. Xanthan gum was used as a matrix. The properties of the films were evaluated using optical microscopy and optical spectrophotometry