Combined effectiveness of Maharasnadi Kashaya with Shunti Churna and Matra Basti with Ksheerabala Taila in Janu Sandhigata Vata (Osteoarthritis Knee) : An open label, single arm clinical study

Sandhi Gata Vata is a clinical condition that comes under the heading of Vata Vyadhi where Prakupita Vata affects Sandhi and causes specific signs and symptoms. Lakshanas of Sandhi Gata Vata of Janu Sandhi resembles the signs and symptoms of osteoarthritis of knee. Osteoarthritis of the knee is more commonly found in women than men, and the prevalence increases dramatically with age. The major risk factors associated with osteoarthritis knee joint are old age, obesity, excessive usage of knee joint (occupational), which makes it an important cause of disability. A clinical study was conducted on 31 subjects by administering combination of Maharsnadi Kashaya with Shunti Churna and Matra Basti with Ksheerabala Taila and the results obtained were statistically analysed. Statistically significant reduction in Lakshanas of Janu Sandhi Gata Vata and WOMAC scores were noted

An open label single arm prospective clinical study on Vatagajankusha Rasa with Pippali Churna and Manjishta Kwatha as Anupana in Pakshaghata (CVA due to Infarct)

Background: Pakshaghata is one among the 80 vataja nanatmaja vikara and is a roga of madhyama roga marga. Vatavyadhi is considered to be one among the ashta mahagadas. Vatagajankusha rasa is a combination of vyosha, bhasmas, vatsanabha, karkatasringi, haritaki etc. It has vatakaphahara, vikasi, vyavayi, rasayana etc properties. It is said to be effective in treating pakshaghata in 7 days if given along with Pippali churna and Manjishta kwatha. Aims and Objectives: To evaluate the efficacy of Vatagajankusha rasa with Pippali churna and Manjishta kwatha as anupana in the management of pakshaghata (CVA due to infarct). Methodology: Among 32 registered patients, 30 completed the course of treatment. They were administered with Vatagajankusha rasa 1 tablet (125 mg) after food with anupana 3gm Pippali churna and 15 ml Manjishta kwatha twice daily (morning and evening) for a period of 7 days. Nominal & ordinal data were analysed using non parametric tests like McNemar and Wilcoxon’s signed rank tests respectively. Result: There was statistically significant improvement in the primary and secondary outcome measures (p<0.05 was observed). Conclusion: Vatagajankusha rasa with Pippali churna and Manjishta kwatha as anupana is effective in the management of Pakshaghata (CVA due to infarct)