Randomised controlled trial comparing rubber band ligation with stapled haemorrhoidopexy for Grade II circumferential haemorrhoids : Long-term results

Peer reviewedPostprin

Comparative analysis of inter population genetic diversity in Puntius filametosus using restriction fragment length polymorphism (RFLP) analysis

The genetic variation in different population of the freshwater cyprinid Puntius filamentosus was studied using restriction fragment length polymorphism (RFLP) analysis. Samples were collected fromfive different locations of southern Western Ghats, India. The morphometric characters of population from Alancholai showed little variation when compared with other population. The genomic size of the different population of P. filamentosus found between 3.45 and 3.80 ng/mg. The result of RFLP analysis showed that the population from Alancholai had distinct fragment length and scored high band volume (12.430 nmoles). The result of cluster analysis showed that Alancholai population had distinct genetic structure and it did not cluster with other population. The study inferred that the population from Alancholai appeared to be unique among the other population of P. filamentosus

DETERMINATION OF BIOACTIVE COMPONENTS OF BARLERIA COURTALLICA NEES (ACANTHACEAE) BY GAS CHROMATOGRAPHY–MASS SPECTROMETRY ANALYSIS

Objective: The present investigation was carried out to determine the possible bioactive components of stem, root, and leaf of Barleria courtallica Nees using a gas chromatography–mass spectrometry (GC-MS).Methods: The phytocomponents of the ethanol extracts of stem, root, and leaf of B. courtallica were investigated using PerkinElmer GC-MS, while the mass spectra of the compounds found in the extracts were matched with the National Institute of Standards and Technology version II library. Results: 25, 23, and 28 compounds were identified in the ethanol extracts of stem, root, and leaf of B. courtallica, respectively. The prevailing compounds of stem were β-sitosterol (20.27%), stigmasterol (17.07%), eicosane, 7-hexyl- (6.64%), 3,7,11,15-tetramethyl-2-hexadecan-1-ol (5.97%), and tetracosane, 11-decyl- (5.91%). The major constituents recorded from root extract of B. courtallica were β-sitosterol (22.94%), stigmasterol (20.17%), urs-12-en-28-oic acid, 3-hydroxy-, methyl ester, (3β)- (18.42%), and eiosane, 7-hexyl- (7.06%). The prevailing compounds of leaf were 3,7,11,15- tetramethyl-2-hexadecan-1-ol (34.42%), phytol (14.18%), β-sitosterol (12.71%), squalene (11.25%), stigmasterol (8.15%), phytol acetate (6.53%). Conclusions: From the results, it is evident that B. courtallica contains various bioactive compounds and is recommended as a plant of phytopharmaceutical importance

Tribological Analysis of Copper-Coated Graphite Particle-Reinforced A359 Al/5 wt.% SiC Composites

[[abstract]]Copper-coated graphite particles can be mass-produced by the cementation process using simple equipment. Graphite particulates that were coated with electroless copper and 5 wt.% SiC particulates were introduced into an aluminum alloy by compocasting to make A359 Al/5 wt.% SiC(p) composite that contained 2, 4, 6, and 8 wt.% graphite particulate composite. The effects of SiC particles, quantity of graphite particles, normal loading, sliding speed and wear debris on the coefficient of friction, and the wear rate were investigated. The results thus obtained indicate that the wear properties were improved by adding small amounts of SiC and graphite particles into the A359 Al alloy. The coefficient of friction of the A359 Al/5 wt.% SiC(p) composite that contained 6.0 wt.% graphite particulates was reduced to 0.246 and the amount of graphite film that was released on the worn surface increased with the graphite particulate content. The coefficient of friction and the wear rate were insensitive to the variation in the sliding speed and normal loading.[[notice]]補正完畢[[incitationindex]]SCI[[booktype]]紙本[[booktype]]電子

PANC Study (Pancreatitis: A National Cohort Study): national cohort study examining the first 30 days from presentation of acute pancreatitis in the UK

Background Acute pancreatitis is a common, yet complex, emergency surgical presentation. Multiple guidelines exist and management can vary significantly. The aim of this first UK, multicentre, prospective cohort study was to assess the variation in management of acute pancreatitis to guide resource planning and optimize treatment. Methods All patients aged greater than or equal to 18 years presenting with acute pancreatitis, as per the Atlanta criteria, from March to April 2021 were eligible for inclusion and followed up for 30 days. Anonymized data were uploaded to a secure electronic database in line with local governance approvals. Results A total of 113 hospitals contributed data on 2580 patients, with an equal sex distribution and a mean age of 57 years. The aetiology was gallstones in 50.6 per cent, with idiopathic the next most common (22.4 per cent). In addition to the 7.6 per cent with a diagnosis of chronic pancreatitis, 20.1 per cent of patients had a previous episode of acute pancreatitis. One in 20 patients were classed as having severe pancreatitis, as per the Atlanta criteria. The overall mortality rate was 2.3 per cent at 30 days, but rose to one in three in the severe group. Predictors of death included male sex, increased age, and frailty; previous acute pancreatitis and gallstones as aetiologies were protective. Smoking status and body mass index did not affect death. Conclusion Most patients presenting with acute pancreatitis have a mild, self-limiting disease. Rates of patients with idiopathic pancreatitis are high. Recurrent attacks of pancreatitis are common, but are likely to have reduced risk of death on subsequent admissions