Electrophilic Cyanate As a Recognition Motif for Reactive Sulfur Species: Selective Fluorescence Detection of H₂S

An ESIPT-based fluorescent dye, 3-hydroxyflavone, is chemically masked with an electrophilic cyanate motif in order to construct a fluorescent probe for cellular sulfur species. This novel probe structure, displays an extremely fast, highly sensitive and selective “turn-on” type fluorescent response toward H₂S. We have also documented its utility for imaging of H₂S in the living cells

BODIPY–Au(I): A Photosensitizer for Singlet Oxygen Generation and Photodynamic Therapy

Upon complexation with Au­(I), a photoinactive BODIPY derivative was transformed into a highly photoactive triplet sensitizer. Along with high efficiency in singlet oxygen generation (Φ_Δ = 0.84), the new BODIPY–Au­(I) skeleton showed excellent photocytotoxic activity against cancer cell lines (EC₅₀ = 2.5 nM)