4 research outputs found
Retrospective Evaluation of Patients Aged 45 Years or Younger Diagnosed with Colorectal Cancer
Aim: The incidence of colorectal carcinoma is less common under
45 years of age when compared to older patients. In the last
decades, the prognosis, pathological, genetic and physiological
behavior of the tumor in young patients gained the attention of the
researchers. It is a reality that nowadays, colorectal cancers are
more commonly encountered in younger population.
Methods: We retrospectively analyzed colorectal cancer patients
who had been under 45 years of age and operated on in our
surgery clinic in a period of 6 years. Forty-one young patients out of
a total of 331 patients with colorectal carcinoma were evaluated.
Gender, age, tumor markers, anemia, pathology reports, in addition
to Dukes classification and histological subtype (mucinous or
non-mucinous) were recorded.
Results: 25 patients were male (61%) and 16 were female
(39%).The most common complaint was restlessness and the most
common type was non-mucinous adenocarcinoma. The most
common locations were rectum and sigmoid colon, in 23 (56%)
and 11 (27%) patients, respectively. While 1 patient (2%) was in
stage A, almost half of the patients (49%) were in stage D.
Conclusion: Colorectal carcinoma in young individuals is usually
encountered in males and is often in advanced stage at time of
diagnosis, in addition to more aggressive behavior when compared
to elderly patients. (The Me di cal Bul le tin of Ha se ki 2011; 49: 110-3