Quantum phase transitions in the Kane-Mele-Hubbard model

We study the two-dimensional Kane-Mele-Hubbard model at half filling by means of quantum Monte Carlo simulations. We present a refined phase boundary for the quantum spin liquid. The topological insulator at finite Hubbard interaction strength is adiabatically connected to the groundstate of the Kane-Mele model. In the presence of spin-orbit coupling, magnetic order at large Hubbard U is restricted to the transverse direction. The transition from the topological band insulator to the antiferromagnetic Mott insulator is in the universality class of the three-dimensional XY model. The numerical data suggest that the spin liquid to topological insulator and spin liquid to Mott insulator transitions are both continuous.Comment: 13 pages, 10 figures; final version; new Figs. 4(b) and 8(b

Robertsonian chromosome polymorphism found in a local herd of the Japanese Black cattle

International audienc

Comment on "Novel Superfluidity in a Trapped Gas of Fermi Atoms with Repulsive Interaction Loaded on an Optical Lattice"

In a recent letter Machida et al. [Phys. Rev. Lett. 93, 200402 (2004)] concluded that in a trapped gas of fermions with repulsive interactions a superfluid phase appears around the Mott-insulator at the center of the trap. They base their conclusion on a negative binding energy, and a large weight for a singlet formed by particles located at opposite sides of the Mott-insulator. We show here that the observed effects are not related to superfluidity.Comment: Revtex file, 1 page, 1 figure, published versio

Midkine in Inflammation

The 13 kDa heparin-binding growth factor midkine (MK) was originally identified as a molecule involved in the orchestration of embryonic development. Recent studies provided evidence for a new role of MK in acute and chronic inflammatory processes. Accordingly, several inflammatory diseases including nephritis, arthritis, atherosclerosis, colitis, and autoimmune encephalitis have been shown to be alleviated in the absence of MK in animal models. Reduced leukocyte recruitment to the sites of inflammation was found to be one important mechanism attenuating chronic inflammation when MK was absent. Furthermore, MK was found to modulate expression of proinflammatory cytokines and the expansion of regulatory T-cells. Here, we review the current understanding of the role of MK in different inflammatory disorders and summarize the knowledge of MK biology

Mott Domains of Bosons Confined on Optical Lattices

In the absence of a confining potential, the boson Hubbard model in its ground state is known to exhibit a superfluid to Mott insulator quantum phase transition at commensurate fillings and strong on-site repulsion. In this paper, we use quantum Monte Carlo simulations to study the ground state of the one dimensional bosonic Hubbard model in a trap. We show that some, but not all, aspects of the Mott insulating phase persist when a confining potential is present. The Mott behavior is present for a continuous range of incommensurate fillings, a very different situation from the unconfined case. Furthermore the establishment of the Mott phase does not proceed via a quantum phase transition in the traditional sense. These observations have important implications for the interpretation of experimental results for atoms trapped on optical lattices. Initial results show that, qualitatively, the same results persist in higher dimensions.Comment: Revtex file, five figures, include

The virtuous cycle of axon growth: Axonal transport of growth-promoting machinery as an intrinsic determinant of axon regeneration

Injury to the brain and spinal cord has devastating consequences because adult central nervous system (CNS) axons fail to regenerate. Injury to the peripheral nervous system (PNS) has a better prognosis, because adult PNS neurons support robust axon regeneration over long distances. CNS axons have some regenerative capacity during development, but this is lost with maturity. Two reasons for the failure of CNS regeneration are extrinsic inhibitory molecules, and a weak intrinsic capacity for growth. Extrinsic inhibitory molecules have been well characterised, but less is known about the neuron-intrinsic mechanisms which prevent axon re-growth. Key signalling pathways and genetic / epigenetic factors have been identified which can enhance regenerative capacity, but the precise cellular mechanisms mediating their actions have not been characterised. Recent studies suggest that an important prerequisite for regeneration is an efficient supply of growth-promoting machinery to the axon, however this appears to be lacking from non-regenerative axons in the adult CNS. In the first part of this review, we summarise the evidence linking axon transport to axon regeneration. We discuss the developmental decline in axon regeneration capacity in the CNS, and comment on how this is paralleled by a similar decline in the selective axonal transport of regeneration-associated receptors such as integrins and growth factor receptors. In the second part, we discuss the mechanisms regulating selective polarised transport within neurons, how these relate to the intrinsic control of axon regeneration, and whether they can be targeted to enhance regenerative capacity.ERA‐NET Neuron International Foundation for Research in Paraplegia Christopher and Dana Reeve Foundation. Grant Numbers: JFC‐2013(3), JFC‐2013(4) Gates Cambridge Trust Medical Research Council. Grant Numbers: G1000864 018556, MR/R004463/