14 research outputs found

    Asymmetric C-C bond formation by the mixed oxidative coupling of 1,1 '-bi-2-naphthyl esters

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    Asymmetric C-C bond formation was effected by the oxidative coupling of two different ester enolates using (R)-(+)-1,1'-bi(2-naphthol) as a common tether which served to link together both ester moieties in an asymmetric environment. Reduction of the corresponding succinates afforded diastereomerically pure 2,3-disubstituted-1,4-butanediols
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