Influence of vitamin B3 on morphosynthesis of CaCO3, BaCO3 and SrCO3 micro and nano structures

Influence of vitamin B3, nicotinic acid has been investigated on crystallization of CaCO3, BaCO3 and SrCO3 as a growth modifier. Well-defined crystals with size range from micro-scale to nano-scale can be easily obtained. Different polymorphs of CaCO3, aggregates of hexagonal rods to nano fibers of BaCO3 and dendrimeric nano structures of SrCO3 could be formed, depending on the reaction conditions. Mineralization of alkali metal carbonates controlled by nicotinic acid is a simple and versatile method for production of materials with different morphologies. The concentration of nicotinic acid has significant influence on the size and growth of the final product. The synthesized products were characterized by X-ray diffraction, FT-IR and Scanning Electron Microscopy (SEM)

Effect of <em>γ</em>-radiation on structure, photoluminescence properties and <em>in vitro</em> cytotoxicity of LaPO₄:Tb³⁺,Ce³⁺ phosphor

784-790Lauric acid capped Ce3+ sensitized LaPO4:Tb3+ nanorods have been synthesized by hydrothermal route at 150 °C. The structure, stability and luminescent properties have been examined by TEM, TG/DTA, FT-IR, powder X-ray diffraction and PL spectral data. Cytotoxic activity has been examined by MTT assay. The LaPO4:Tb3+,Ce3+ phosphor exhibits four emission peaks at 485, 551, 583 and 619 nm corresponding to 5D4→7F6, 5D4→7F5, 5D4→7F4 and 5D4→7F3 transitions, respectively. The influence of γ-radiation on photoluminescence properties of LaPO4:Tb3+,Ce3+ phosphor has also been examined at 5 and 300 kGy. Furthermore, LaPO4 and LaPO4:Tb3+,Ce3+ phosphors exhibit 80–82% cytotoxic effect against breast cancer cell lines, MDA-MB 231 and MCF-7. The IC50 values for LaPO4 and LaPO4:Tb3+,Ce3+ phosphors are 17.2 and 13.5 µg/mL against MCF-7 and 21.5 and 15.0 µg/mL against MDA-MB 231 cell line, respectively