QUALITY CHARACTERIZATION OF MADHUYASHTI GHRITA

Madhuyashti Ghrita, is an Ayurvedic medicated ghee preparation containing Yashtimadhu. It is used for treating external ulcers and wounds in vital points of the body. However, there is no quality monograph available for Madhuyashti Ghrita. Hence, the present work was carried out to characterize this Ghrita to confirm its identity, quality and purity. This work reported various pharmacognostic and physicochemical parameters of Madhuyashti Ghrita along with its TLC based rapid fingerprinting as per the present standards of Ayurvedic Pharmacopoeia of India. Moreover, the presence of toxic contaminants like heavy metals, and microbial load were also evaluated. In organoleptic evaluation, the Ghrita was found to be semi–solid and dark yellow in colour, sweet and bitter in taste with a characteristic and pleasant odour. The values of the physicochemical parameters such as acid value, saponification value, peroxide value, refractive index, rancidity and pH value of the Ghrita were also assed. In the microscopical analysis of the rhizomes of Yashtimadhu, the presence of pitted vessels, fibres, prismatic crystals and starch grains were noted as a confirmation characteristic for the genuinely of this raw material in Madhuyashti Ghrita. The amount of heavy metals such arsenic, lead, mercury, cadmium, nickel, zinc, copper and chromium as well as total bacterial count and total fungal count were found to be much below their API limits. The TLC showed different characteristic spots indicating the presence of Yashtimadhu in this product. The parameters of Madhuyashti Ghrita presented in this paper may be utilized for preparing a quality monograph for this product

ESTABLISHMENT OF QUALITY CONTROL PARAMETERS OF PANCHASAKARA CHURNA - A CLASSICAL AYURVEDIC FORMULATION

Objective: Standardization of any herbal formulation is essential in order to assess the quality, purity, safety, and efficacy of drugs based on the analysis of their active properties. Testing of Ayurvedic preparations using scientific methodologies adds to quality and authenticity of the product.Methods: This article reports standardization parameters for a classical Ayurvedic formulation Panchasakara Churna. In this paper, the formulation was prepared as per Ayurvedic Formulary of India and was characterized by pharmacognostic, physical, physicochemical, phytochemical, toxicological parameters as well as thin layer chromatography (TLC) profiling using standard methodologies.Results: This experimental work provided diagnostic characteristics to identify and standardize the formulation Panchasakara Churna prepared using its official ingredients.Conclusion: Based on the present investigation results, a monograph on quality standards for Panchasakara Churna can be proposed for its batch-to-batch consistency. This document can also be utilised for rapid authentication fingerprints of this formulation using its TLC profiling.Keywords: Panchasakara Churna, Toxicological, Chromatography, Microscopi

Pharmacognostic, physicochemical and chromatographic characterization of Samasharkara Churna

Background: Samasharkara Churna, a polyherbal Ayurvedic formulation, is prescribed for treating various conditions such as asthma and cough. Literature review suggested that characterization parameters of Samasharkara Churna are not reported. Objective: To report characteristic parameters of Samasharkara Churna to conform its identity, quality and purity. Materials and Methods: Samasharkara Churna was evaluated for pharmacognostic, physicochemical, microbiological, and chromatographic parameters. Results: The chromatographic analysis was able to showed presence of all ingredients in Samasharkara Churna. Conclusion: The characterization parameters presented in this paper may serve as standard reference for the quality control analysis of Samasharkara Churna