Attitudes and impressions of participants in a study of the causes of childhood cancer

Researchers and ethics committees are increasingly concerned about the perceived emotional impact on individuals following participation in epidemiologic studies. This attitudinal survey was designed to investigate this issue among 751 of the parents who had already given an interview in the UK Childhood Cancer Study (UKCCS), one of the largest case-control studies ever undertaken to investigate the aetiology of cancer in children. Information was collected by postal questionnaire on their reasons for agreeing to take part in the UKCCS, on whether questions had caused distress or difficulty and what their feelings were immediately after the interview and at the time of this survey. Parents were asked if they felt they had benefited in any way by taking part and control parents were asked if they would have taken part without prior consent of their doctor. 90% of both cases and controls felt glad to have taken part immediately after the interview and few reported any anxiety at having done so; 95% of both cases and controls felt satisfied that they had made a worthwhile contribution. Although 18% of cases felt tense and 14% felt unhappy after the interview, over 90% of them felt glad that they had taken part a few weeks later. Of particular interest is that 38% of cases and 24% of controls said they had positively benefited from taking part in the UKCCS and 96% of control mothers did not mind their family doctor giving permission for them to be contacted. © 2001 Cancer Research Campaign http://www.bjcancer.co

Bathymetry and Sediment Geochemistry of Lake Hazen (Quttinirpaaq National Park, Ellesmere Island, Nunavut)

Arctic lakes can provide a long-term perspective on environmental change, including trends in long-range atmospheric transport and deposition of contaminants, inferred from studies of sediment cores. In this study, we conducted the first detailed bathymetric survey of Lake Hazen (Quttinirpaaq National Park, Ellesmere Island, Nunavut), the world’s largest lake north of 74˚ latitude. With these data we were able to determine optimal locations for sediment coring and to collect and analyze profundal sediment cores. A bathymetric map of Lake Hazen was developed on the basis of 362 spot soundings obtained with GPS-coupled sounding equipment placed directly on the ice combined with additional soundings from a small boat. The deepest point in the lake (81˚49.5ʹ N; 70˚42.8ʹ W) was found to be 267 m deep. The lake volume was estimated to be 5.14 × 1010 m3, about 10% larger than previous estimates. Using estimates of the discharge of Lake Hazen from the Water Survey of Canada, we estimated the water retention time to be 89 years. Sediment cores were dated using 210Pb and 137Cs. Sedimentation rates at the deep point, estimated using the Constant Rate of Supply model for excess 210Pb, were relatively high (1260 g m-2yr-1) in the period 2005 – 1963 and lower (650 ± 100 g m-2yr-1) in horizons dated to 1950 – 1880. The majority of elements measured in sediment (24 of 29 consistently above detection limits), as well as organic carbon, showed less than 20% variation in concentrations in the top 10 cm (compacted depth), which represent deposition over approximately 140 years. Geochemical characteristics of the sediment suggest that erosional inputs from annual glacial melting are the major source of essentially all elements and that anthropogenic inputs from long-range transport of toxic metals such as mercury and lead are very low.Les lacs de l’Arctique peuvent fournir une perspective à long terme en matière de changement environnemental, notamment en ce qui a trait aux tendances relatives au transport atmosphérique et au dépôt de contaminants sur de longues périodes, tendances inférées à partir d’études de carottes de sédiments. Dans le cadre de la présente étude, nous avons effectué le premier levé bathymétrique détaillé du lac Hazen (parc national Quttinirpaaq, île d’Ellesmere, Nunavut), le plus grand lac de la planète situé au nord de 74˚ de latitude. Grâce aux données prélevées, nous avons réussi à déterminer les meilleurs emplacements pour le prélèvement de carottes de sédiments de même que pour la collecte et l’analyse de carottes de sédiments profonds. Une carte bathymétrique du lac Hazen a été dressée en fonction de 362 sondages obtenus au moyen de matériel d’appareils phoniques dotés de GPS placés directement sur la glace et supplémentés par des sondages recueillis à partir d’un petit bateau. Le point le plus profond du lac (81˚49,5ʹ N; 70˚42,8ʹ O) a été trouvé à 267 m de profondeur. Le volume du lac a été évalué à 5,14 × 1010 m3, soit 10 % de plus que les évaluations précédentes. À l’aide d’estimations du déversement du lac Hazen obtenues auprès de la Division des relevés hydrologiques du Canada, nous avons évalué que la durée de rétention de l’eau était de 89 ans. La datation des carottes de sédiments a été faite à l’aide de 210Pb et de 137Cs. Les taux de sédimentation au point profond, estimés en s’appuyant sur le modèle CRS (Constant Rate of Supply) pour l’excédent 210Pb, étaient relativement élevés (1260 g m-2an-1) pour la période allant de 2005 à 1963, et moins élevés (650 ± 100 g m-2an-1) pour la période de 1950 à 1880. La majorité des éléments mesurés dans les sédiments (24 sur 29 étaient uniformément au-dessus des seuils de détection) ainsi que dans le carbone organique ont produit une variation de concentrations de moins de 20 % dans les 10 cm supérieurs (profondeur compactée), ce qui représente des dépôts s’échelonnant sur environ 140 ans. Les caractéristiques géochimiques des sédiments laissent présumer que les matières d’érosion découlant de la fonte glaciaire annuelle constituent la source principale de sensiblement tous les éléments, et que les matières anthropiques provenant du transport à grande distance de métaux toxiques, tels que le mercure et le plomb, sont très faibles

Micromechanics of seismic wave propagation in granular materials

In this study experimental data on a model soil in a cubical cell are compared with both discrete element (DEM) simulations and continuum analyses. The experiments and simulations used point source transmitters and receivers to evaluate the shear and compression wave velocities of the samples, from which some of the elastic moduli can be deduced. Complex responses to perturbations generated by the bender/extender piezoceramic elements in the experiments were compared to those found by the controlled movement of the particles in the DEM simulations. The generally satisfactory agreement between experimental observations and DEM simulations can be seen as a validation and support the use of DEM to investigate the influence of grain interaction on wave propagation. Frequency domain analyses that considered filtering of the higher frequency components of the inserted signal, the ratio of the input and received signals in the frequency domain and sample resonance provided useful insight into the system response. Frequency domain analysis and analytical continuum solutions for cube vibration show that the testing configuration excited some, but not all, of the system’s resonant frequencies. The particle scale data available from DEM enabled analysis of the energy dissipation during propagation of the wave. Frequency domain analysis at the particle scale revealed that the higher frequency content reduces with increasing distance from the point of excitation

Blaming Bill Gates AGAIN! Misuse, overuse and misunderstanding of performance data in sport

Recently in Sport, Education and Society, Williams and Manley (2014) argued against the heavy reliance on technology in professional Rugby Union and elite sport in general. In summary, technology is presented as an elitist, ‘gold standard’ villain that management and coaches use to exert control and by which players lose autonomy, identity, motivation, social interactions and expertise. In this article we suggest that the sociological interpretations and implications offered by Williams and Manley may be somewhat limited when viewed in isolation. In doing so, we identify some core methodological issues in Williams and Manley’s study and critically consider important arguments for utilising technology; notably, to inform coach decision making and generate player empowerment. Secondly, we present a different, yet perhaps equally concerning, practice-oriented interpretation of the same results but from alternative coaching and expertise literature. Accordingly, we suggest that Williams and Manley have perhaps raised their alarm prematurely, inappropriately and on somewhat shaky foundations. We also hope to stimulate others to consider contrary positions, or at least to think about this topic in greater detail. More specifically, we encourage coaches and academics to think carefully about what technology is employed, how and why, and then the means by which these decisions are discussed with and, preferably, sold to players. Certainly, technology can significantly enhance coach decision making and practice, while also helping players to optimise their focus, empowerment and independence in knowing how to achieve their personal and collective goals

Tunneling and Quantum Noise in 1-D Luttinger Liquids

We study non-equilibrium noise in the transmission current through barriers in 1-D Luttinger liquids and in the tunneling current between edges of fractional quantum Hall liquids. The distribution of tunneling events through narrow barriers can be described by a Coulomb gas lying in the time axis along a Keldysh (or non-equilibrium) contour. The charges tend to reorganize as a dipole gas, which we use to describe the tunneling statistics. Intra-dipole correlations contribute to the high-frequency ``Josephson'' noise, which has an algebraic singularity at $\omega=e^*V/\hbar$, whereas inter-dipole correlations are responsible for the low-frequency noise. Inter-dipole interactions give a $1/t^2$ correlation between the tunneling events that results in a $|\omega|$ singularity in the noise spectrum. We present a diagrammatic technique to calculate the correlations in perturbation theory, and show that contributions from terms of order higher than the dipole-dipole interaction should only affect the strength of the $|\omega|$ singularity, but its form should remain $\sim |\omega|$ to all orders in perturbation theory.Comment: RevTex, 9 figures available upon request, cond-mat/yymmnn

Enhancement of the Deuteron-Fusion Reactions in Metals and its Experimental Implications

Recent measurements of the reaction d(d,p)t in metallic environments at very low energies performed by different experimental groups point to an enhanced electron screening effect. However, the resulting screening energies differ strongly for divers host metals and different experiments. Here, we present new experimental results and investigations of interfering processes in the irradiated targets. These measurements inside metals set special challenges and pitfalls which make them and the data analysis particularly error-prone. There are multi-parameter collateral effects which are crucial for the correct interpretation of the observed experimental yields. They mainly originate from target surface contaminations due to residual gases in the vacuum as well as from inhomogeneities and instabilities in the deuteron density distribution in the targets. In order to address these problems an improved differential analysis method beyond the standard procedures has been implemented. Profound scrutiny of the other experiments demonstrates that the observed unusual changes in the reaction yields are mainly due to deuteron density dynamics simulating the alleged screening energy values. The experimental results are compared with different theoretical models of the electron screening in metals. The Debye-H\"{u}ckel model that has been previously proposed to explain the influence of the electron screening on both nuclear reactions and radioactive decays could be clearly excluded.Comment: 22 pages, 12 figures, REVTeX4, 2-column format. Submitted to Phys. Rev. C; accepte

Integration of professional judgement and decision-making in high-level adventure sports coaching practice

This study examined the integration of professional judgement and decision-making processes in adventure sports coaching. The study utilised a thematic analysis approach to investigate the decision-making practices of a sample of high-level adventure sports coaches over a series of sessions. Results revealed that, in order to make judgements and decisions in practice, expert coaches employ a range of practical and pedagogic management strategies to create and opportunistically use time for decision-making. These approaches include span of control and time management strategies to facilitate the decision-making process regarding risk management, venue selection, aims, objectives, session content, and differentiation of the coaching process. The implication for coaches, coach education, and accreditation is the recognition and training of the approaches that“create time” for the judgements in practice, namely“creating space to think”. The paper concludes by offering a template for a more expertise-focused progression in adventure sports coachin

Higher analogues of the discrete-time Toda equation and the quotient-difference algorithm

The discrete-time Toda equation arises as a universal equation for the relevant Hankel determinants associated with one-variable orthogonal polynomials through the mechanism of adjacency, which amounts to the inclusion of shifted weight functions in the orthogonality condition. In this paper we extend this mechanism to a new class of two-variable orthogonal polynomials where the variables are related via an elliptic curve. This leads to a `Higher order Analogue of the Discrete-time Toda' (HADT) equation for the associated Hankel determinants, together with its Lax pair, which is derived from the relevant recurrence relations for the orthogonal polynomials. In a similar way as the quotient-difference (QD) algorithm is related to the discrete-time Toda equation, a novel quotient-quotient-difference (QQD) scheme is presented for the HADT equation. We show that for both the HADT equation and the QQD scheme, there exists well-posed $s$-periodic initial value problems, for almost all \s\in\Z^2. From the Lax-pairs we furthermore derive invariants for corresponding reductions to dynamical mappings for some explicit examples.Comment: 38 page

Influence of dissipation on the extraction of quantum states via repeated measurements

A quantum system put in interaction with another one that is repeatedly measured is subject to a non-unitary dynamics, through which it is possible to extract subspaces. This key idea has been exploited to propose schemes aimed at the generation of pure quantum states (purification). All such schemes have so far been considered in the ideal situations of isolated systems. In this paper, we analyze the influence of non-negligible interactions with environment during the extraction process, with the scope of investigating the possibility of purifying the state of a system in spite of the sources of dissipation. A general framework is presented and a paradigmatic example consisting of two interacting spins immersed in a bosonic bath is studied. The effectiveness of the purification scheme is discussed in terms of purity for different values of the relevant parameters and in connection with the bath temperature.Comment: 10 pages, 3 figure