2,3-Dimethyl-N-[(E)-4-nitro­benzyl­idene]aniline

In the title compound, C15H14N2O2, the aromatic rings are oriented at a dihedral angle of 24.52 (5)°. The dihedral angle between the nitro group and its parent benzene ring is 9.22 (16)°. In the crystal, mol­ecules inter­act through aromatic π—π stacking inter­actions [centroid–centroid separations = 3.8158 (14) and 3.9139 (14) Å]

Microbial transformation of the steroidal alkaloid dictyophlebine by Rhizopus stolonifer

Devkota KP, Choudhary MI, Nawaz SA, et al. Microbial transformation of the steroidal alkaloid dictyophlebine by Rhizopus stolonifer. Chemical & Pharmaceutical Bulletin. 2007;55(4):682-684.The microbial transformation of a steroidal alkaloid, dictyophlebine (1) with Rhizopus stolonifer (ATCC 10404) afforded three oxidized metabolites 2-4. Compound 2 was found to be a new product. These metabolites were structurally characterized on the basis of modern spectroscopic techniques. Their inhibitory activity towards acetyl- and butyrylcholinesterase has been evaluated and the new product 2 has been found to be more potent than the parent compound and other metabolites