1 research outputs found
Ag and MoO<sub>3</sub> Nanoparticle-Containing Polyacrylonitrile Nanofiber Membranes for Wound Dressings
Herein,
we report the effect of different reducing agents
on Ag-MoO3/polyacrylonitrile nanofibers for their promising
potential
as advanced wound dressings. The nanofibers were treated with NaOH,
NaBH4, sodium citrate, and UV light, and their properties
were evaluated. Water contact angle measurements revealed that NaOH
treatment resulted in a less wettable surface, while NaBH4 and sodium citrate treatments led to more wettable surfaces. UV
light treatment induced a slight increase in the surface wettability.
Antibacterial inhibition zone tests showed that NaOH and UV treatments
exhibited significant inhibitory effects against both Escherichia
coli and Bacillus subtilis, while NaBH4 and sodium citrate treatments displayed moderate inhibitory
effects. Moreover, silver release profiles demonstrated a sustained
release of silver ions over time, with sodium citrate treatment exhibiting
a higher release rate. MoO3/polyacrylonitrile displayed
a substantially lower stress value, 73% less than that of the blank
polyacrylonitrile (PAN) nanofiber. This decrease in the stress value
is advantageous for wound dressings, as it allows for improved flexibility
and conformability to the wound site. Overall, these findings provide
insights into the surface wettability, antimicrobial properties, and
silver ion release capabilities of Ag-MoO3/polyacrylonitrile
nanofibers under different treatments, highlighting their potential
for wound dressing applications