447 research outputs found

    The Role of Scanning, Evaluation, and Mindfulness in the Assimilation of Information Technology: The Case of Enterprise Resource Planning (ERP) Systems

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    Enterprise Resource Planning Systems (ERPs) are commercial software packages that enable integration of information and business processes throughout the organization. Realizing the business value of information technology (IT) requires its successful assimilation by the firm. ERP assimilation refers to the effective application of this type of IT in supporting a firm's business strategies and value-chain activities. To succeed at this, the IS function must continuously manage the adaptation between the organization and the ERP system, even after initial deployment. For this purpose, the IS function must continuously scan both the firm's internal and external environment to identify new ERP adaptation opportunities that will allow the effective application of new ERP technologies to support the firm's objectives. Also, it is important for the IS function to engage in evaluation activities to analyze and select those ERP adaptation opportunities with the greatest potential for impact on ERP assimilation. It is posited here that ERP scanning will have a direct positive effect on the firm's level of ERP assimilation, and that this effect will be moderated by the extent of ERP evaluation activities. IS mindfulness, the degree of collective mindfulness present in the IS function, is also posited to moderate the relationship between ERP scanning and ERP assimilation. Collective mindfulness is an elevated state of alertness toward expectations, in the face of new and unprecedented situations or changes, with a nuanced appreciation of the specific context. IS mindfulness makes more likely the identification and realization of unexpected ERP adaptation opportunities leading to a higher level of ERP assimilation for the firm. A model is proposed to describe the relations among IS mindfulness, ERP scanning, ERP evaluation, and ERP assimilation. This model has been tested by collecting survey data from 113 firms. The results suggest that first, collective mindfulness is a construct with two dimensions: alertness/attention, a state of vigilant alertness, and change/situation, an awareness or knowledge of an unprecedented situation or change in the firm's environment; second, scanning of the internal environment (scanning of needs) has a main effect on ERP assimilation, and this effect is moderated by the presence of IS mindfulness ("alertness" dimension), as predicted by the model; and third, ERP evaluation has rather a direct effect on ERP assimilation and does not moderate the scanning-assimilation relationship as expected

    The Content of the Basic/Required MIS Course in a Latin-American MBA

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    The panel is about the basic/required MIS course in Latin-American MBA programs. Given the current insufficiency of qualified MIS faculty in Latin-America this course is frequently taught by faculty from other areas and its content is often highly technical. The panel (introduced and moderated by Dr. Carlos Ferran) will discuss the current and the ideal content of this course as well as avenues to move forward. Two panelists are resident faculty in Latin-American universities (Dr. Aurora Sanchez –UCNA in Chile– and Dr. David Montesinos –INCAE in Costa Rica–), one visits Latin-America regularly to teach MIS in MBA programs (Dr. Enrique Mu), and one is completely unrelated to Latin-America (Dr. Janis Gogan) who will question why the course should be any different to the ones taught elsewhere. The panel is of interest to Latin-American academics but also for any academic interested on what should be included in the basic/required MIS course in MBA programs regardless of geography

    Pancreatic Exocrine Insufficiency as a Complication of Gastrointestinal Surgery and the Impact of Pancreatic Enzyme Replacement Therapy

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    BACKGROUND: Pancreatic exocrine insufficiency (PEI) is characterized by inadequate production, insufficient secretion, and/or inactivation of pancreatic enzymes, resulting in maldigestion. The aim of this review was to analyze the prevalence and pathophysiology of PEI resulting from gastrointestinal (GI) surgery and to examine the use of pancreatic enzyme replacement therapy (PERT) for effectively managing PEI. SUMMARY: A targeted PubMed search was conducted for studies examining the prevalence and pathophysiology of PEI in patients following GI surgery and for studies assessing the effects of PERT in these patients. PEI is a common complication following GI surgery that can lead to nutritional deficiencies, which may contribute to morbidity and mortality in patients. Timely treatment of PEI with PERT can prevent malnutrition, increase quality of life, and possibly reduce the associated mortality. Treatment of PEI should aim not only to alleviate symptoms but also to achieve significant improvements in nutritional parameters. Dose optimization of PERT is required for effective management of PEI, in addition to regular assessment of nutritional status, appropriate patient education, and reassessment if symptoms return. Key Messages: Difficulties in detecting PEI following GI surgery can result in undiagnosed and untreated maldigestion, leading to metabolic complications and increased morbidity. Both are preventable by early administration and monitoring for optimal doses of PERT

    Multidisciplinary consensus statement on the clinical management of patients with pancreatic cancer

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    Pancreatic cancer (PC) remains one of the most aggressive tumors with an increasing incidence rate and reduced survival. Although surgical resection is the only potentially curative treatment for PC, only 15-20% of patients are resectable at diagnosis. To select the most appropriate treatment and thus improve outcomes, the diagnostic and therapeutic strategy for each patient with PC should be discussed within a multidisciplinary expert team. Clinical decision-making should be evidence-based, considering the staging of the tumor, the performance status and preferences of the patient. The aim of this guideline is to provide practical and evidence-based recommendations for the management of PC

    Differences in In Vitro Properties of Pancreatin Preparations for Pancreatic Exocrine Insufficiency as Marketed in Russia and CIS

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    BACKGROUND: Pancreatic enzyme-replacement therapy (PERT), provided as pancreatin to patients with pancreatic exocrine insufficiency (PEI), is considered an essential substitute for the pivotal physiological function the pancreas fulfills in digestion. PEI involves a reduction in the synthesis and secretion of pancreatic enzymes (lipase, protease, amylase), which leads to an inadequate enzymatic response to a meal and consequently to maldigestion and malabsorption of nutrients. The efficacy of PERT is strongly dependent on enzyme activity, dissolution, and pancreatin particle size. OBJECTIVE: The physiological properties of eight pancreatin preparations (nine batches; five different brands) available in Russia and CIS (Commonwealth of Independent States: Armenia, Azerbaijan, Belarus, Kazakhstan, Kyrgyzstan, Moldova, Russia, Tajikistan, Uzbekistan) were investigated. METHODS: The lipase activity, dissolution, and particle size distribution of samples from multiple batches of pancreatin of different strengths were measured. RESULTS: Regarding lipase activities, all pancreatin preparations except Micrazim(R) matched the labeled content. Considerable differences were observed in particle size and dissolution. CONCLUSION: Pancreatin preparations available in Russia and CIS demonstrate product-to-product and batch-to-batch variability regarding the measured properties of lipase activity, dissolution, and particle size. This may impact the efficacy of PERT and therefore clinical outcomes
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