High visceral leishmaniasis mortality rate in Barra Mansa, a new area of visceral leishmaniasis transmission in the State of Rio de Janeiro, Brazil

Submitted by Janaína Nascimento ([email protected]) on 2019-02-25T13:56:59Z No. of bitstreams: 1 ve_Pimentel_Maria_etal_INI_2014.pdf: 682300 bytes, checksum: 4e3bfdd78a8d38cf7d46a986e2b14e94 (MD5)Approved for entry into archive by Janaína Nascimento ([email protected]) on 2019-02-26T12:23:26Z (GMT) No. of bitstreams: 1 ve_Pimentel_Maria_etal_INI_2014.pdf: 682300 bytes, checksum: 4e3bfdd78a8d38cf7d46a986e2b14e94 (MD5)Made available in DSpace on 2019-02-26T12:23:26Z (GMT). No. of bitstreams: 1 ve_Pimentel_Maria_etal_INI_2014.pdf: 682300 bytes, checksum: 4e3bfdd78a8d38cf7d46a986e2b14e94 (MD5) Previous issue date: 2014Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Laboratório de Vigilância em Leishmanioses. Rio de Janeiro, RJ, Brasil / Secretaria de Estado de Saúde do Rio de Janeiro. Gerência de Doenças Transmitidas por Vetores e Zoonoses. Rio de Janeiro, RJ, Brasil.Secretaria Municipal de Saúde de Barra Mansa. Coordenação de Vigilância Epidemiológica. Barra Mansa, RJ, Brasil.Santa Casa de Misericórdia de Barra Mansa. Barra Mansa, RJ, Brasil.Secretaria de Estado de Saúde do Rio de Janeiro. Gerência de Doenças Transmitidas por Vetores e Zoonoses. Rio de Janeiro, RJ, Brasil.Secretaria de Estado de Saúde do Rio de Janeiro. Gerência de Doenças Transmitidas por Vetores e Zoonoses. Rio de Janeiro, RJ, Brasil.Santa Casa de Misericórdia de Barra Mansa. Barra Mansa, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Laboratório de Vigilância em Leishmanioses. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Laboratório de Vigilância em Leishmanioses. Rio de Janeiro, RJ, Brasil / Fundação Carlos Chagas Filho de Amparo à Pesquisa no Estado do Rio de Janeiro. Rio de Janeiro, RJ, Brasil.Introduction: Nine cases of visceral leishmaniasis occurred recently in Barra Mansa, State of Rio de Janeiro, with a high mortality rate. Methods: We reviewed the medical records of the patients. Results: Eight were male; 7 were adults. Patients who died progressed to death quickly and presented with aggravating factors: systemic steroid therapy before diagnosis, bleeding, severe liver involvement, infection, and/or refusal to receive transfusion. Conclusions: We warn clinicians to be aware of the emergence of visceral leishmaniasis in new areas and to keep in mind the possibility of atypical clinical pictures and aggravating factors, so timely diagnosis can be made and prompt and adequate treatment can be initiated

High visceral leishmaniasis mortality rate in Barra Mansa, a new area of visceral leishmaniasis transmission in the State of Rio de Janeiro, Brazil

Introduction Nine cases of visceral leishmaniasis occurred recently in Barra Mansa, State of Rio de Janeiro, with a high mortality rate. Methods We reviewed the medical records of the patients. Results Eight were male; 7 were adults. Patients who died progressed to death quickly and presented with aggravating factors: systemic steroid therapy before diagnosis, bleeding, severe liver involvement, infection, and/or refusal to receive transfusion. Conclusions We warn clinicians to be aware of the emergence of visceral leishmaniasis in new areas and to keep in mind the possibility of atypical clinical pictures and aggravating factors, so timely diagnosis can be made and prompt and adequate treatment can be initiated