2 research outputs found
Neuropsychological Aspects in Neurosurgical Patients with Glial Tumours // ΠΠ΅Π²ΡΠΎΠΏΡΠΈΡ ΠΎΠ»ΠΎΠ³ΠΈΡΠ½ΠΈ Π°ΡΠΏΠ΅ΠΊΡΠΈ ΠΏΡΠΈ Π½Π΅Π²ΡΠΎΡ ΠΈΡΡΡΠ³ΠΈΡΠ½ΠΈ ΠΏΠ°ΡΠΈΠ΅Π½ΡΠΈ Ρ Π³Π»ΠΈΠ°Π»Π½ΠΈ ΡΡΠΌΠΎΡΠΈ
Cognitive dysfunction refers to damage to one or more cognitive areas, from the following: executive functions, memory, attention, language functions, and visuospatial functions. These may be present before initiating the initial treatment in the preoperative period of the patients, even presenting a normal neurological status on assessment. With regard to targeted studies of glial tumours, different authors report between 19% and 95% cognitive function impairment in the studied groups of newly diagnosed patients. However, regardless of the rate of cognitive impairment at the time of diagnosis of a glial brain tumour, cognitive impairment occurs in all patients at some later stage of the disease. The tumour itself may cause this deficit, the subsequent treatment or a combination of both. Cognitive functions are used for long-term follow-up of neuro-oncology patients due to their proven prognostic value in life expectancy and disease recurrence. This necessitates more extensive pre- and post-operative follow-up of the cognitive status of these patients.
The thesis aims to find a short screening method for diagnosing cognitive impairment in neurosurgical patients with glial tumours that is affordable, reliable and convenient for application in daily neurosurgical practice.ΠΠ° ΠΊΠΎΠ³Π½ΠΈΡΠΈΠ²Π½Π° Π΄ΠΈΡΡΡΠ½ΠΊΡΠΈΡ ΡΠ΅ Π³ΠΎΠ²ΠΎΡΠΈ ΠΏΡΠΈ ΡΠ²ΡΠ΅Π΄Π° Π½Π° Π΅Π΄Π½Π° ΠΈΠ»ΠΈ ΠΏΠΎΠ²Π΅ΡΠ΅ ΠΊΠΎΠ³Π½ΠΈΡΠΈΠ²Π½ΠΈ ΠΎΠ±Π»Π°ΡΡΠΈ, ΠΎΡ ΡΠ»Π΅Π΄Π½ΠΈΡΠ΅: Π΅ΠΊΠ·Π΅ΠΊΡΡΠΈΠ²Π½ΠΈ ΡΡΠ½ΠΊΡΠΈΠΈ, ΠΏΠ°ΠΌΠ΅Ρ, Π²Π½ΠΈΠΌΠ°Π½ΠΈΠ΅, Π΅Π·ΠΈΠΊΠΎΠ²ΠΈ ΡΡΠ½ΠΊΡΠΈΠΈ, Π²ΠΈΠ·ΡΠ°Π»Π½ΠΎΠΏΡΠΎΡΡΡΠ°Π½ΡΡΠ²Π΅Π½ΠΈ ΡΡΠ½ΠΊΡΠΈΠΈ. Π’Π΅ ΠΌΠΎΠ³Π°Ρ Π΄Π° ΡΠ° Π½Π°Π»ΠΈΡΠ½ΠΈ ΠΏΡΠ΅Π΄ΠΈ Π·Π°ΠΏΠΎΡΠ²Π°Π½Π΅ΡΠΎ Π½Π° ΠΈΠ½ΠΈΡΠΈΠ°Π»Π½ΠΎΡΠΎ Π»Π΅ΡΠ΅Π½ΠΈΠ΅ Π² ΠΏΡΠ΅Π΄ΠΎΠΏΠ΅ΡΠ°ΡΠΈΠ²Π½ΠΈΡ ΠΏΠ΅ΡΠΈΠΎΠ΄ Π½Π° ΠΏΠ°ΡΠΈΠ΅Π½ΡΠΈΡΠ΅, Π΄ΠΎΡΠΈ ΠΏΡΠΈ Π½ΠΎΡΠΌΠ°Π»Π΅Π½ Π½Π΅Π²ΡΠΎΠ»ΠΎΠ³ΠΈΡΠ΅Π½ ΡΡΠ°ΡΡΡ. ΠΠΎ ΠΎΡΠ½ΠΎΡΠ΅Π½ΠΈΠ΅ Π½Π° Π³Π»ΠΈΠ°Π»Π½ΠΈΡΠ΅ ΡΡΠΌΠΎΡΠΈ, ΠΏΡΠΈ Π½Π°ΡΠΎΡΠ΅Π½ΠΎ ΠΈΠ·ΡΠ»Π΅Π΄Π²Π°Π½Π΅ ΡΠ°Π·Π»ΠΈΡΠ½ΠΈΡΠ΅ Π°Π²ΡΠΎΡΠΈ Π΄ΠΎΠΊΠ»Π°Π΄Π²Π°Ρ ΠΌΠ΅ΠΆΠ΄Ρ 19% ΠΈ 95% Π·Π°ΡΡΠ³Π°Π½Π΅ Π½Π° ΠΊΠΎΠ³Π½ΠΈΡΠΈΠ²Π½ΠΈΡΠ΅ ΡΡΠ½ΠΊΡΠΈΠΈ Π½Π° ΠΈΠ·ΡΠ»Π΅Π΄Π²Π°Π½Π°ΡΠ° Π³ΡΡΠΏΠ° Π½ΠΎΠ²ΠΎΠ΄ΠΈΠ°Π³Π½ΠΎΡΡΠΈΡΠΈΡΠ°Π½ΠΈ ΠΏΠ°ΡΠΈΠ΅Π½ΡΠΈ. ΠΠΎ Π±Π΅Π· Π·Π½Π°ΡΠ΅Π½ΠΈΠ΅ ΠΎΡ ΠΏΡΠΎΡΠ΅Π½ΡΠ° Π½Π° ΠΊΠΎΠ³Π½ΠΈΡΠΈΠ²Π½ΠΎ ΡΠ²ΡΠ΅ΠΆΠ΄Π°Π½Π΅ Π² ΠΌΠΎΠΌΠ΅Π½ΡΠ° Π½Π° ΠΏΠΎΡΡΠ°Π²ΡΠ½Π΅ Π½Π° Π΄ΠΈΠ°Π³Π½ΠΎΠ·Π° Π³Π»ΠΈΠ°Π»Π΅Π½ ΠΌΠΎΠ·ΡΡΠ΅Π½ ΡΡΠΌΠΎΡ, ΠΊΠΎΠ³Π½ΠΈΡΠΈΠ²Π½ΠΈΡΠ΅ Π½Π°ΡΡΡΠ΅Π½ΠΈΡ ΡΠ΅ ΠΏΡΠΎΡΠ²ΡΠ²Π°Ρ ΠΏΡΠΈ Π²ΡΠΈΡΠΊΠΈ ΠΏΠ°ΡΠΈΠ΅Π½ΡΠΈ Π² Π½ΡΠΊΠΎΠΈ ΠΎΡ ΡΠ»Π΅Π΄Π²Π°ΡΠΈΡΠ΅ ΡΡΠ°Π΄ΠΈΠΈ Π½Π° ΡΠ°Π·Π²ΠΈΡΠΈΠ΅ Π½Π° Π·Π°Π±ΠΎΠ»ΡΠ²Π°Π½Π΅ΡΠΎ. Π’ΠΎΠ·ΠΈ Π΄Π΅ΡΠΈΡΠΈΡ ΠΌΠΎΠΆΠ΅ Π΄Π° ΡΠ΅ Π΄ΡΠ»ΠΆΠΈ Π½Π° ΡΠ°ΠΌΠΈΡ ΡΡΠΌΠΎΡ, Π½Π° ΠΏΠΎΡΠ»Π΅Π΄Π²Π°ΡΠΎΡΠΎ Π³ΠΎ Π»Π΅ΡΠ΅Π½ΠΈΠ΅ ΠΈΠ»ΠΈ Π½Π° ΠΊΠΎΠΌΠ±ΠΈΠ½Π°ΡΠΈΡ ΠΎΡ Π΄Π²Π΅ΡΠ΅. ΠΠΎΠ³Π½ΠΈΡΠΈΠ²Π½ΠΈΡΠ΅ ΡΡΠ½ΠΊΡΠΈΠΈ ΡΠ»ΡΠΆΠ°Ρ Π·Π° Π΄ΡΠ»Π³ΠΎΡΡΠΎΡΠ½ΠΎ ΠΏΡΠΎΡΠ»Π΅Π΄ΡΠ²Π°Π½Π΅ Π½Π° Π½Π΅Π²ΡΠΎΠΎΠ½ΠΊΠΎΠ»ΠΎΠ³ΠΈΡΠ½ΠΈΡΠ΅ Π±ΠΎΠ»Π½ΠΈ ΠΏΠΎΡΠ°Π΄ΠΈ ΡΡΡ
Π½Π°ΡΠ° Π΄ΠΎΠΊΠ°Π·Π°Π½Π° ΠΏΡΠΎΠ³Π½ΠΎΡΡΠΈΡΠ½Π° ΡΡΠΎΠΉΠ½ΠΎΡΡ ΠΏΠΎ ΠΎΡΠ½ΠΎΡΠ΅Π½ΠΈΠ΅ Π½Π° ΠΏΡΠΎΠ΄ΡΠ»ΠΆΠΈΡΠ΅Π»Π½ΠΎΡΡΡΠ° Π½Π° ΠΆΠΈΠ²ΠΎΡ ΠΈ ΡΠ΅ΡΠΈΠ΄ΠΈΠ² Π½Π° Π·Π°Π±ΠΎΠ»ΡΠ²Π°Π½Π΅ΡΠΎ. Π’ΠΎΠ²Π° Π½Π°Π»Π°Π³Π° ΠΏΠΎ-ΠΎΠ±ΡΡΠΎΠΉΠ½ΠΎΡΠΎ ΠΏΡΠ΅Π΄- ΠΈ ΠΏΠΎΡΡΠΎΠΏΠ΅ΡΠ°ΡΠΈΠ²Π½ΠΎ ΠΏΡΠΎΡΠ»Π΅Π΄ΡΠ²Π°Π½Π΅ Π½Π° ΠΊΠΎΠ³Π½ΠΈΡΠΈΠ²Π½ΠΈΡ ΡΡΠ°ΡΡΡ Π½Π° ΡΠ΅Π·ΠΈ ΠΏΠ°ΡΠΈΠ΅Π½ΡΠΈ.
Π¦Π΅Π»: ΠΠ° ΡΠ΅ ΠΎΡΠΊΡΠΈΠ΅ ΠΊΡΠ°ΡΡΠΊ ΡΠΊΡΠΈΠ½ΠΈΠ½Π³ΠΎΠ² ΠΌΠ΅ΡΠΎΠ΄ Π·Π° Π΄ΠΈΠ°Π³Π½ΠΎΡΡΠΈΡΠΈΡΠ°Π½Π΅ Π½Π° ΠΊΠΎΠ³Π½ΠΈΡΠΈΠ²Π½ΠΈΡΠ΅ Π½Π°ΡΡΡΠ΅Π½ΠΈΡ ΠΏΡΠΈ Π½Π΅Π²ΡΠΎΡ
ΠΈΡΡΡΠ³ΠΈΡΠ½ΠΈ ΠΏΠ°ΡΠΈΠ΅Π½ΡΠΈ Ρ Π³Π»ΠΈΠ°Π»Π½ΠΈ ΡΡΠΌΠΎΡΠΈ, ΠΊΠΎΠΉΡΠΎ Π΄Π° Π΅ Π΄ΠΎΡΡΡΠΏΠ΅Π½, Π΄Π° Π΄Π°Π²Π° Π΄ΠΎΡΡΠΎΠ²Π΅ΡΠ½ΠΈ ΡΠ΅Π·ΡΠ»ΡΠ°ΡΠΈ ΠΈ Π΄Π° Π΅ Π΄ΠΎΡΡΠ°ΡΡΡΠ½ΠΎ ΡΠ΄ΠΎΠ±Π΅Π½ Π·Π° ΠΏΡΠΈΠ»ΠΎΠΆΠ΅Π½ΠΈΠ΅ Π² Π΅ΠΆΠ΅Π΄Π½Π΅Π²Π½Π°ΡΠ° Π½Π΅Π²ΡΠΎΡ
ΠΈΡΡΡΠ³ΠΈΡΠ½Π° ΠΏΡΠ°ΠΊΡΠΈΠΊΠ°