2 research outputs found

    Neuropsychological Aspects in Neurosurgical Patients with Glial Tumours // НСвропсихологични аспСкти ΠΏΡ€ΠΈ Π½Π΅Π²Ρ€ΠΎΡ…ΠΈΡ€ΡƒΡ€Π³ΠΈΡ‡Π½ΠΈ ΠΏΠ°Ρ†ΠΈΠ΅Π½Ρ‚ΠΈ с Π³Π»ΠΈΠ°Π»Π½ΠΈ Ρ‚ΡƒΠΌΠΎΡ€ΠΈ

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    Cognitive dysfunction refers to damage to one or more cognitive areas, from the following: executive functions, memory, attention, language functions, and visuospatial functions. These may be present before initiating the initial treatment in the preoperative period of the patients, even presenting a normal neurological status on assessment. With regard to targeted studies of glial tumours, different authors report between 19% and 95% cognitive function impairment in the studied groups of newly diagnosed patients. However, regardless of the rate of cognitive impairment at the time of diagnosis of a glial brain tumour, cognitive impairment occurs in all patients at some later stage of the disease. The tumour itself may cause this deficit, the subsequent treatment or a combination of both. Cognitive functions are used for long-term follow-up of neuro-oncology patients due to their proven prognostic value in life expectancy and disease recurrence. This necessitates more extensive pre- and post-operative follow-up of the cognitive status of these patients. The thesis aims to find a short screening method for diagnosing cognitive impairment in neurosurgical patients with glial tumours that is affordable, reliable and convenient for application in daily neurosurgical practice.Π—Π° ΠΊΠΎΠ³Π½ΠΈΡ‚ΠΈΠ²Π½Π° дисфункция сС Π³ΠΎΠ²ΠΎΡ€ΠΈ ΠΏΡ€ΠΈ ΡƒΠ²Ρ€Π΅Π΄Π° Π½Π° Π΅Π΄Π½Π° ΠΈΠ»ΠΈ ΠΏΠΎΠ²Π΅Ρ‡Π΅ ΠΊΠΎΠ³Π½ΠΈΡ‚ΠΈΠ²Π½ΠΈ области, ΠΎΡ‚ слСднитС: Π΅ΠΊΠ·Π΅ΠΊΡƒΡ‚ΠΈΠ²Π½ΠΈ Ρ„ΡƒΠ½ΠΊΡ†ΠΈΠΈ, ΠΏΠ°ΠΌΠ΅Ρ‚, Π²Π½ΠΈΠΌΠ°Π½ΠΈΠ΅, Π΅Π·ΠΈΠΊΠΎΠ²ΠΈ Ρ„ΡƒΠ½ΠΊΡ†ΠΈΠΈ, визуалнопространствСни Ρ„ΡƒΠ½ΠΊΡ†ΠΈΠΈ. Π’Π΅ ΠΌΠΎΠ³Π°Ρ‚ Π΄Π° са Π½Π°Π»ΠΈΡ‡Π½ΠΈ ΠΏΡ€Π΅Π΄ΠΈ Π·Π°ΠΏΠΎΡ‡Π²Π°Π½Π΅Ρ‚ΠΎ Π½Π° ΠΈΠ½ΠΈΡ†ΠΈΠ°Π»Π½ΠΎΡ‚ΠΎ Π»Π΅Ρ‡Π΅Π½ΠΈΠ΅ Π² прСдопСративния ΠΏΠ΅Ρ€ΠΈΠΎΠ΄ Π½Π° ΠΏΠ°Ρ†ΠΈΠ΅Π½Ρ‚ΠΈΡ‚Π΅, Π΄ΠΎΡ€ΠΈ ΠΏΡ€ΠΈ Π½ΠΎΡ€ΠΌΠ°Π»Π΅Π½ Π½Π΅Π²Ρ€ΠΎΠ»ΠΎΠ³ΠΈΡ‡Π΅Π½ статус. По ΠΎΡ‚Π½ΠΎΡˆΠ΅Π½ΠΈΠ΅ Π½Π° Π³Π»ΠΈΠ°Π»Π½ΠΈΡ‚Π΅ Ρ‚ΡƒΠΌΠΎΡ€ΠΈ, ΠΏΡ€ΠΈ насочСно изслСдванС Ρ€Π°Π·Π»ΠΈΡ‡Π½ΠΈΡ‚Π΅ Π°Π²Ρ‚ΠΎΡ€ΠΈ Π΄ΠΎΠΊΠ»Π°Π΄Π²Π°Ρ‚ ΠΌΠ΅ΠΆΠ΄Ρƒ 19% ΠΈ 95% засяганС Π½Π° ΠΊΠΎΠ³Π½ΠΈΡ‚ΠΈΠ²Π½ΠΈΡ‚Π΅ Ρ„ΡƒΠ½ΠΊΡ†ΠΈΠΈ Π½Π° изслСдваната Π³Ρ€ΡƒΠΏΠ° новодиагностицирани ΠΏΠ°Ρ†ΠΈΠ΅Π½Ρ‚ΠΈ. Но Π±Π΅Π· Π·Π½Π°Ρ‡Π΅Π½ΠΈΠ΅ ΠΎΡ‚ ΠΏΡ€ΠΎΡ†Π΅Π½Ρ‚Π° Π½Π° ΠΊΠΎΠ³Π½ΠΈΡ‚ΠΈΠ²Π½ΠΎ ΡƒΠ²Ρ€Π΅ΠΆΠ΄Π°Π½Π΅ Π² ΠΌΠΎΠΌΠ΅Π½Ρ‚Π° Π½Π° поставянС Π½Π° Π΄ΠΈΠ°Π³Π½ΠΎΠ·Π° Π³Π»ΠΈΠ°Π»Π΅Π½ ΠΌΠΎΠ·ΡŠΡ‡Π΅Π½ Ρ‚ΡƒΠΌΠΎΡ€, ΠΊΠΎΠ³Π½ΠΈΡ‚ΠΈΠ²Π½ΠΈΡ‚Π΅ Π½Π°Ρ€ΡƒΡˆΠ΅Π½ΠΈΡ сС проявяват ΠΏΡ€ΠΈ всички ΠΏΠ°Ρ†ΠΈΠ΅Π½Ρ‚ΠΈ Π² някои ΠΎΡ‚ слСдващитС стадии Π½Π° Ρ€Π°Π·Π²ΠΈΡ‚ΠΈΠ΅ Π½Π° заболяванСто. Π’ΠΎΠ·ΠΈ Π΄Π΅Ρ„ΠΈΡ†ΠΈΡ‚ ΠΌΠΎΠΆΠ΅ Π΄Π° сС дълТи Π½Π° самия Ρ‚ΡƒΠΌΠΎΡ€, Π½Π° послСдващото Π³ΠΎ Π»Π΅Ρ‡Π΅Π½ΠΈΠ΅ ΠΈΠ»ΠΈ Π½Π° комбинация ΠΎΡ‚ Π΄Π²Π΅Ρ‚Π΅. ΠšΠΎΠ³Π½ΠΈΡ‚ΠΈΠ²Π½ΠΈΡ‚Π΅ Ρ„ΡƒΠ½ΠΊΡ†ΠΈΠΈ слуТат Π·Π° Π΄ΡŠΠ»Π³ΠΎΡΡ€ΠΎΡ‡Π½ΠΎ прослСдяванС Π½Π° Π½Π΅Π²Ρ€ΠΎΠΎΠ½ΠΊΠΎΠ»ΠΎΠ³ΠΈΡ‡Π½ΠΈΡ‚Π΅ Π±ΠΎΠ»Π½ΠΈ ΠΏΠΎΡ€Π°Π΄ΠΈ тяхната Π΄ΠΎΠΊΠ°Π·Π°Π½Π° прогностична стойност ΠΏΠΎ ΠΎΡ‚Π½ΠΎΡˆΠ΅Π½ΠΈΠ΅ Π½Π° ΠΏΡ€ΠΎΠ΄ΡŠΠ»ΠΆΠΈΡ‚Π΅Π»Π½ΠΎΡΡ‚Ρ‚Π° Π½Π° ΠΆΠΈΠ²ΠΎΡ‚ ΠΈ Ρ€Π΅Ρ†ΠΈΠ΄ΠΈΠ² Π½Π° заболяванСто. Π’ΠΎΠ²Π° Π½Π°Π»Π°Π³Π° ΠΏΠΎ-обстойното ΠΏΡ€Π΅Π΄- ΠΈ постопСративно прослСдяванС Π½Π° когнитивния статус Π½Π° Ρ‚Π΅Π·ΠΈ ΠΏΠ°Ρ†ΠΈΠ΅Π½Ρ‚ΠΈ. Π¦Π΅Π»: Π”Π° сС ΠΎΡ‚ΠΊΡ€ΠΈΠ΅ ΠΊΡ€Π°Ρ‚ΡŠΠΊ скринингов ΠΌΠ΅Ρ‚ΠΎΠ΄ Π·Π° диагностициранС Π½Π° ΠΊΠΎΠ³Π½ΠΈΡ‚ΠΈΠ²Π½ΠΈΡ‚Π΅ Π½Π°Ρ€ΡƒΡˆΠ΅Π½ΠΈΡ ΠΏΡ€ΠΈ Π½Π΅Π²Ρ€ΠΎΡ…ΠΈΡ€ΡƒΡ€Π³ΠΈΡ‡Π½ΠΈ ΠΏΠ°Ρ†ΠΈΠ΅Π½Ρ‚ΠΈ с Π³Π»ΠΈΠ°Π»Π½ΠΈ Ρ‚ΡƒΠΌΠΎΡ€ΠΈ, ΠΊΠΎΠΉΡ‚ΠΎ Π΄Π° Π΅ Π΄ΠΎΡΡ‚ΡŠΠΏΠ΅Π½, Π΄Π° Π΄Π°Π²Π° достовСрни Ρ€Π΅Π·ΡƒΠ»Ρ‚Π°Ρ‚ΠΈ ΠΈ Π΄Π° Π΅ Π΄ΠΎΡΡ‚Π°Ρ‚ΡŠΡ‡Π½ΠΎ ΡƒΠ΄ΠΎΠ±Π΅Π½ Π·Π° ΠΏΡ€ΠΈΠ»ΠΎΠΆΠ΅Π½ΠΈΠ΅ Π² Π΅ΠΆΠ΅Π΄Π½Π΅Π²Π½Π°Ρ‚Π° Π½Π΅Π²Ρ€ΠΎΡ…ΠΈΡ€ΡƒΡ€Π³ΠΈΡ‡Π½Π° ΠΏΡ€Π°ΠΊΡ‚ΠΈΠΊΠ°
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