The Grizzly, November 8, 2001

Construction on Campus Continues as Scheduled • UC Leadership Scholars Attend Annual Halloween Concert • An Evening with Alice Parker a Musical Success • Peace Corps and City Year Representatives Speak About Careers in Common Good • Anthrax Vaccine at Center of Controversy • Opinions: Closed Courses and Wait Lists: Nightmares of Registration; Pop Goes the Quiz! • Gospel Choir Sings out for Peace, Prayer and Healing; Concert a Great Success • Judy Chicago is Coming! World-famous Artist to Visit Ursinus • Influenza Season is Upon Us • Comparative Prices on Museums • Self Protection Facts: What You Need to Know • Power of Dance • Rushing Season Begins Again • Gettysburg Becomes New CC Men\u27s Soccer Champion • UC Women\u27s Rugby Fighting the Good Fight • NCAA Volleyball Semi-finals • UC Downs FDUhttps://digitalcommons.ursinus.edu/grizzlynews/1500/thumbnail.jp

The Grizzly, November 29, 2001

UC Blueskies Calls for Help with Recycling • AIDS Legacy Continues in Poor Countries • Economics and Business Administration Panel Discussion Offers Students Advice on Finding Job Connections • Volunteers Wanted for NBA League Jam Session • UC Group Makes Plans for Alternative Spring Break • New California Law Enables Women to Obtain Emergency Contraceptive Pills without a Prescription • Opinions: So This is Christmas?; Family Bonding is Better than Trip to Spain; Letter of Apology • Messiah to Hit the Stage • Jazz Ensemble Keeps it Swinging • Comparative Pricing: Local Gasoline • Dougherty Finishes 123rd at Nationals • 8+6+9 = Success for UC Wrestling Team • Lady Bears Knocked off by Susquehanna • Duncan Selected as a Finalist for the Gagliardi Trophy • Captains Leading the Way to Victory for Bears Swimming • Bears Basketball Still Looking for First Winhttps://digitalcommons.ursinus.edu/grizzlynews/1502/thumbnail.jp

The Grizzly, November 15, 2001

Second Annual Operation Christmas Child a Success Thanks to the Holiday Spirit in UC Students • Ribbon Cutting Ceremony Held to Dedicate the New Floy Lewis Bakes Field House • With a New Face Comes Changes at Zack\u27s • SASA Sponsors Bizarre Turkey Contest • Ursinus Students Help in Election Campaign • Career Services Helps Misdirected Students • Great American Smokeout Turns Twenty-Five • Opinions: Thanksgiving not Really a Holiday at Ursinus; Zack\u27s: Think Twice About That Price; Take Three Advil: The Universal Cure from the Wellness Center • Cheesecake Factory far from a Cheesy Experience • The Glass Menagerie is Coming to Ursinus! • Open Mic Night Steals the Stage! • Olevian Hall: The First Women\u27s Dormitory at Ursinus • Advantages and Disadvantages of Working at the Mall this Holiday Season • Club Review • The Real Deal About Birth Control • UC Swimming Left to Choke on the Wake of Swarthmore • The New, Buffer, Women\u27s Basketball Team • Four Athletes Attempt to Save Passengers of Flight 93 • Ursinus Performs Exorcism on Devils • Going Deep with the Ursinus Scuba Diving Team • Dougherty Headed to Nationalshttps://digitalcommons.ursinus.edu/grizzlynews/1501/thumbnail.jp

The Grizzly, October 18, 2001

Sisters of Omega Chi Sponsor Blood Drive • Taking a Hike with the Environmental Studies Classes • World Cultures Club Encourages Campus-Wide Cultural Awareness • Gil Cook and Heather Potts Named 2001 Homecoming King and Queen • Understanding the Social Norms at Ursinus College • Ursinus Bookstore Holding Coat and Blanket Drive • Ursinus Alumna Martha Kriebel Reflects on the Unexpected Turns in Life\u27s Path • The Economic Effects of Terrorism • Struggling to Survive: The Way of Life for Women in Afghanistan • From Mexico to Collegeville: International Exchange Student Enrique Cobarrubias • Sophomore Week: Helping Students Reach Academic Goals • Second Annual Take Back the Night Rally & March Planned for Next Week • Opinions: Lady Wismer Attacks Students Saying Next Time, I\u27m Gonna Nail You! ; A Student\u27s Battle with Smoking; New Gym is Great, not Awkward; Message of Tolerance and Peace; One Resident Complains: Loss of Interest in Special Interest Houses • Dr. David Releases his own CD • New Road Brewhouse Ready to Rock! • Scary Way to Have a Fun Fall Day • Chinese Food: The Staple of Every College Student\u27s Diet • Can\u27t Decide What to do after Graduation? This Online Program Will Help • Class of 2003 has a new President • Ruby\u27s Restaurant: A Tasty Time Capsule • Give the Wismer Staff a Break: They\u27re Working for You • Who is Grizzly the Bear? • Ursinus Field Hockey Takes Victory over Holy Cross • Bears Wake from Hibernation; Crush Gettysburg 31-7 • Men\u27s Soccer Meets Gettysburg • Volleyball Wins Against Bryn Mawr and U. of the Sciences • XC Cleans up at Lehigh University • Barth Becomes Record-holder for Points • Field Hockey Changing NCAA Division • Women\u27s Soccer Rocks the Househttps://digitalcommons.ursinus.edu/grizzlynews/1497/thumbnail.jp

Dietary flavanols and procyanidin oligomers from cocoa (Theobroma cacao) inhibit platelet function

© 2003 American Society for Clinical NutritionBackground: Flavonoids may be partly responsible for some health benefits, including antiinflammatory action and a decreased tendency for the blood to clot. An acute dose of flavanols and oligomeric procyanidins from cocoa powder inhibits platelet activation and function over 6 h in humans. Objective: This study sought to evaluate whether 28 d of supplementation with cocoa flavanols and related procyanidin oligomers would modulate human platelet reactivity and primary hemostasis and reduce oxidative markers in vivo. Design: Thirty-two healthy subjects were assigned to consume active (234 mg cocoa flavanols and procyanidins/d) or placebo (≤ 6 mg cocoa flavanols and procyanidins/d) tablets in a blinded parallel-designed study. Platelet function was determined by measuring platelet aggregation, ATP release, and expression of activation-dependent platelet antigens by using flow cytometry. Plasma was analyzed for oxidation markers and antioxidant status. Results: Plasma concentrations of epicatechin and catechin in the active group increased by 81% and 28%, respectively, during the intervention period. The active group had significantly lower P selectin expression and significantly lower ADP-induced aggregation and collagen-induced aggregation than did the placebo group. Plasma ascorbic acid concentrations were significantly higher in the active than in the placebo group (P < 0.05), whereas plasma oxidation markers and antioxidant status did not change in either group. Conclusions: Cocoa flavanol and procyanidin supplementation for 28 d significantly increased plasma epicatechin and catechin concentrations and significantly decreased platelet function. These data support the results of acute studies that used higher doses of cocoa flavanols and procyanidins.Karen J. Murphy, Andriana K. Chronopoulos, Indu Singh, Maureen A. Francis, Helen Moriarty, Marilyn J. Pike, Alan H. Turner, Neil J. Mann, and Andrew J. Sinclai

Antibiotics-First Versus Surgery for Appendicitis: A US Pilot Randomized Controlled Trial Allowing Outpatient Antibiotic Management

Study objectiveRandomized trials suggest that nonoperative treatment of uncomplicated appendicitis with antibiotics-first is safe. No trial has evaluated outpatient treatment and no US randomized trial has been conducted, to our knowledge. This pilot study assessed feasibility of a multicenter US study comparing antibiotics-first, including outpatient management, with appendectomy.MethodsPatients aged 5 years or older with uncomplicated appendicitis at 1 US hospital were randomized to appendectomy or intravenous ertapenem greater than or equal to 48 hours and oral cefdinir and metronidazole. Stable antibiotics-first-treated participants older than 13 years could be discharged after greater than or equal to 6-hour emergency department (ED) observation with next-day follow-up. Outcomes included 1-month major complication rate (primary) and hospital duration, pain, disability, quality of life, and hospital charges, and antibiotics-first appendectomy rate.ResultsOf 48 eligible patients, 30 (62.5%) consented, of whom 16 (53.3%) were randomized to antibiotics-first and 14 (46.7%) to appendectomy. Median age was 33 years (range 9 to 73 years), median WBC count was 15,000/μL (range 6,200 to 23,100/μL), and median computed tomography appendiceal diameter was 10 mm (range 7 to 18 mm). Of 15 antibiotic-treated adults, 14 (93.3%) were discharged from the ED and all had symptom resolution. At 1 month, major complications occurred in 2 appendectomy participants (14.3%; 95% confidence interval [CI] 1.8% to 42.8%) and 1 antibiotics-first participant (6.3%; 95% CI 0.2% to 30.2%). Antibiotics-first participants had less total hospital time than appendectomy participants, 16.2 versus 42.1 hours, respectively. Antibiotics-first-treated participants had less pain and disability. During median 12-month follow-up, 2 of 15 antibiotics-first-treated participants (13.3%; 95% CI 3.7% to 37.9%) developed appendicitis and 1 was treated successfully with antibiotics; 1 had appendectomy. No more major complications occurred in either group.ConclusionA multicenter US trial comparing antibiotics-first to appendectomy, including outpatient management, is feasible to evaluate efficacy and safety