Oxygen transfer in the solid-state cultivation of D. Monoceras on polyurethane foam as an inert support

In recent years, there has been a resurgence of interest concerning solid-state cultivation processes due to a number of advantages over submerged cultivation. However, studies on oxygen transfer and the performance of bioreactors are lacking. Processes that use inert supports loaded with chemically-defined liquid media have several potential applications and offer numerous advantages, such as improved process control and monitoring and enhanced process consistency compared with cultivation on natural solid substrates. The aim of this research was to study the oxygen transfer for the production of allergenic proteins from a biomass of Drechslera (Helminthosporium) monoceras cultured in a packed-bed reactor filled with polyurethane foam. The results show that a high protein concentration can be produced on an inert support with a high overall oxygen transfer coefficient (KLa) during cultivation334793799CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICO - CNPQCOORDENAÇÃO DE APERFEIÇOAMENTO DE PESSOAL DE NÍVEL SUPERIOR - CAPESsem informaçã

Evaluating the semantic web: a task-based approach

The increased availability of online knowledge has led to the design of several algorithms that solve a variety of tasks by harvesting the Semantic Web, i.e. by dynamically selecting and exploring a multitude of online ontologies. Our hypothesis is that the performance of such novel algorithms implicity provides an insight into the quality of the used ontologies and thus opens the way to a task-based evaluation of the Semantic Web. We have investigated this hypothesis by studying the lessons learnt about online ontologies when used to solve three tasks: ontology matching, folksonomy enrichment, and word sense disambiguation. Our analysis leads to a suit of conclusions about the status of the Semantic Web, which highlight a number of strengths and weaknesses of the semantic information available online and complement the findings of other analysis of the Semantic Web landscape

ACS Observations of a Strongly Lensed Arc in a Field Elliptical

We report the discovery of a strongly lensed arc system around a field elliptical galaxy in Hubble Space Telescope (HST) Advanced Camera for Surveys (ACS) images of a parallel field observed during NICMOS observations of the HST Ultra-Deep Field. The ACS parallel data comprise deep imaging in the F435W, F606W, F775W, and F850LP bandpasses. The main arc is at a radius of 1.6 arcsec from the galaxy center and subtends about 120 deg. Spectroscopic follow-up at Magellan Observatory yields a redshift z=0.6174 for the lensing galaxy, and we photometrically estimate z_phot = 2.4\pm0.3 for the arc. We also identify a likely counter-arc at a radius of 0.6 arcsec, which shows structure similar to that seen in the main arc. We model this system and find a good fit to an elliptical isothermal potential of velocity dispersion $\sigma \approx 300$ \kms, the value expected from the fundamental plane, and some external shear. Several other galaxies in the field have colors similar to the lensing galaxy and likely make up a small group.Comment: Accepted for publication in ApJ Letters. 10 pages, 3 figures. Figures have been degraded to meet size limit; a higher resolution version and addtional pictures available at http://acs.pha.jhu.edu/~jpb/UDFparc

Methylparaben concentration in commercial Brazilian local anesthetics solutions

FAPESP - FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULOTo detect the presence and concentration of methylparaben in cartridges of commercial Brazilian local anesthetics. Twelve commercial brands (4 in glass and 8 in plastic cartridges) of local anesthetic solutions for use in dentistry were purchased from the Brazilian market and analyzed. Different lots of the commercial brands were obtained in different Brazilian cities (Piracicaba, Campinas and Sao Paulo). Separation was performed using high performance liquid chromatography (HPLC) with UV-Vis detector. The mobile phase used was acetonitrile: water (75:25 - v/v), pH 4.5, adjusted with acetic acid at a flow rate of 1.0 ml.min(-1). When detected in the solutions, the methylparaben concentration ranged from 0.01% (m/v) to 0.16% (m/v). One glass and all plastic cartridges presented methylparaben. 1. Methylparaben concentration varied among solutions from different manufacturers, and it was not indicated in the drug package inserts; 2. Since the presence of methylparaben in dental anesthetics is not regulated by the Brazilian National Health Surveillance Agency (ANVISA) and this substance could cause allergic reactions, it is important to alert dentists about its possible presence204444448FAPESP - FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULOFAPESP - FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULOsem informaçã

Decolonising violence against women research: a study design for co-developing violence prevention interventions with communities in low and middle income countries (LMICs)

BACKGROUND: There has been substantial progress in research on preventing violence against women and girls (VAWG) in the last 20 years. While the evidence suggests the potential of well-designed curriculum-based interventions that target known risk factors of violence at the community level, this has certain limitations for working in partnership with communities in low- and middle-income (LMIC) countries, particularly when it comes to addressing the power dynamics embedded within north-south research relationships. METHODS: As an alternative approach, we outline the study design for the EVE Project: a formative research project implemented in partnership with community-based researchers in Samoa and Amantaní (Peru) using a participatory co-design approach to VAWG prevention research. We detail the methods we will use to overcome the power dynamics that have been historically embedded in Western research practices, including: collaboratively defining and agreeing research guidelines before the start of the project, co-creating theories of change with community stakeholders, identifying local understandings of violence to inform the selection and measurement of potential outcomes, and co-designing VAWG prevention interventions with communities. DISCUSSION: Indigenous knowledge and ways of thinking have often been undermined historically by Western research practices, contributing to repeated calls for better recognition of Southern epistemologies. The EVE Project design outlines our collective thinking on how to address this gap and to further VAWG prevention through the meaningful participation of communities affected by violence in the research and design of their own interventions. We also discuss the significant impact of the COVID-19 pandemic on the project in ways that have both disrupted and expanded the potential for a better transfer of power to the communities involved. This article offers specific strategies for integrating Southern epistemologies into VAWG research practices in four domains: ethics, theories of change, measurement, and intervention design. Our aim is to create new spaces for engagement between indigenous ways of thinking and the evidence that has been established from the past two decades of VAWG prevention research and practice

Atomic mass dependence of \Xi^- and \overline{\Xi}^+ production in central 250 GeV \pi^- nucleon interactions

We present the first measurement of the atomic mass dependence of central \Xi^- and \overline{\Xi}^+ production. It is measured using a sample of 22,459 \Xi^-'s and \overline{\Xi}^+'s produced in collisions between a 250 GeV \pi^- beam and targets of beryllium, aluminum, copper, and tungsten. The relative cross sections are fit to the two parameter function \sigma_0 A^\alpha, where A is the atomic mass. We measure \alpha = 0.924+-0.020+-0.025, for Feynman-x in the range -0.09 < x_F < 0.15.Comment: 10 pages, revtex, 2 figures, submitted to Phys. Rev.

Discovery of a Very Bright Strongly-Lensed Galaxy Candidate at z ~ 7.6

Using HST and Spitzer IRAC imaging, we report the discovery of a very bright strongly lensed Lyman break galaxy (LBG) candidate at z~7.6 in the field of the massive galaxy cluster Abell 1689. The galaxy candidate, which we refer to as A1689-zD1, shows a strong z-J break of at least 2.2 mag and is completely undetected (<1 sigma) in HST/ACS g, r, i, and z-band data. These properties, combined with the very blue J-H and H-[4.5] colors, are exactly the properties of an z~7.6 LBG and can only be reasonably fit by a star-forming galaxy at z=7.6 +/- 0.4. Attempts to reproduce these properties with a model galaxy at z<4 yield particularly poor fits. A1689-zD1 has an observed (lensed) magnitude of 24.7 AB (8 sigma) in the NICMOS H band and is ~1.3 mag brighter than the brightest-known z-dropout galaxy. When corrected for the cluster magnification of 9.3 at z~7.6, the candidate has an intrinsic magnitude of H=27.1 AB, or about an L* galaxy at z~7.6. The source-plane deprojection shows that the star formation is occurring in compact knots of size ~<300 pc. The best-fit stellar population synthesis models yield a median redshift of 7.6, stellar masses (1.6-3.9) x 10^9 M_sun, stellar ages 45-320 Myr, star-formation rates ~<7.6 M_sun/yr, and low reddening with A_V <= 0.3. These properties are generally similar to those of LBGs found at z~5-6. The inferred stellar ages suggest a formation redshift of z~8-10 (t~<0.63 Gyr). A1689-zD1 is the brightest observed, highly reliable z>7.0 galaxy candidate found to date.Comment: Accepted for publication in the Astrophysical Journal, 8 pages, 8 figures, updated to match version in pres

A novel semi-fragile forensic watermarking scheme for remote sensing images

Peer-reviewedA semi-fragile watermarking scheme for multiple band images is presented. We propose to embed a mark into remote sensing images applying a tree structured vector quantization approach to the pixel signatures, instead of processing each band separately. The signature of themmultispectral or hyperspectral image is used to embed the mark in it order to detect any significant modification of the original image. The image is segmented into threedimensional blocks and a tree structured vector quantizer is built for each block. These trees are manipulated using an iterative algorithm until the resulting block satisfies a required criterion which establishes the embedded mark. The method is shown to be able to preserve the mark under lossy compression (above a given threshold) but, at the same time, it detects possibly forged blocks and their position in the whole image.Se presenta un esquema de marcas de agua semi-frágiles para múltiples imágenes de banda. Proponemos incorporar una marca en imágenes de detección remota, aplicando un enfoque de cuantización del vector de árbol estructurado con las definiciones de píxel, en lugar de procesar cada banda por separado. La firma de la imagen hiperespectral se utiliza para insertar la marca en el mismo orden para detectar cualquier modificación significativa de la imagen original. La imagen es segmentada en bloques tridimensionales y un cuantificador de vector de estructura de árbol se construye para cada bloque. Estos árboles son manipulados utilizando un algoritmo iteractivo hasta que el bloque resultante satisface un criterio necesario que establece la marca incrustada. El método se muestra para poder preservar la marca bajo compresión con pérdida (por encima de un umbral establecido) pero, al mismo tiempo, detecta posiblemente bloques forjados y su posición en la imagen entera.Es presenta un esquema de marques d'aigua semi-fràgils per a múltiples imatges de banda. Proposem incorporar una marca en imatges de detecció remota, aplicant un enfocament de quantització del vector d'arbre estructurat amb les definicions de píxel, en lloc de processar cada banda per separat. La signatura de la imatge hiperespectral s'utilitza per inserir la marca en el mateix ordre per detectar qualsevol modificació significativa de la imatge original. La imatge és segmentada en blocs tridimensionals i un quantificador de vector d'estructura d'arbre es construeix per a cada bloc. Aquests arbres són manipulats utilitzant un algoritme iteractiu fins que el bloc resultant satisfà un criteri necessari que estableix la marca incrustada. El mètode es mostra per poder preservar la marca sota compressió amb pèrdua (per sobre d'un llindar establert) però, al mateix temps, detecta possiblement blocs forjats i la seva posició en la imatge sencera

The Transformation of Cluster Galaxies at Intermeidate Redshift

We combine imaging data from the Advanced Camera for Surveys (ACS) with VLT/FORS optical spectroscopy to study the properties of star-forming galaxies in the z=0.837 cluster CL0152-1357. We have morphological information for 24 star-forming cluster galaxies, which range in morphology from late-type and irregular to compact early-type galaxies. We find that while most star-forming galaxies have $r_{625}-i_{775}$ colors bluer than 1.0, eight are in the red cluster sequence. Among the star-forming cluster population we find five compact early-type galaxies which have properties consistent with their identification as progenitors of dwarf elliptical galaxies. The spatial distribution of the star-forming cluster members is nonuniform. We find none within $R\sim 500$ Mpc of the cluster center, which is highly suggestive of an intracluster medium interaction. We derive star formation rates from [OII] $\lambda\lambda 3727$ line fluxes, and use these to compare the global star formation rate of CL0152-1357 to other clusters at low and intermediate redshifts. We find a tentative correlation between integrated star formation rates and $T_{X}$, in the sense that hotter clusters have lower integrated star formation rates. Additional data from clusters with low X-ray temperatures is needed to confirm this trend. We do not find a significant correlation with redshift, suggesting that evolution is either weak or absent between z=0.2-0.8.Comment: ApJ accepte