Early life conditions and financial risk–taking in older age

Using life-history survey data from eleven European countries, we investigate whether childhood conditions, such as socioeconomic status, cognitive abilities and health problems influence portfolio choice and risk attitudes later in life. After controlling for the corresponding conditions in adulthood, we find that superior cognitive skills in childhood (especially mathematical abilities) are positively associated with stock and mutual fund ownership. Childhood socioeconomic status, as indicated by the number of rooms and by having at least some books in the house during childhood, is also positively associated with the ownership of stocks, mutual funds and individual retirement accounts, as well as with the willingness to take financial risks. On the other hand, less risky assets like bonds are not affected by early childhood conditions. We find only weak effects of childhood health problems on portfolio choice in adulthood. Finally, favorable childhood conditions affect the transition in and out of risky asset ownership, both by making divesting less likely and by facilitating investing (i.e., transitioning from non-ownership to ownership)

Transport properties of armchair graphene nanoribbon junctions between graphene electrodes

The transmission properties of armchair graphene nanoribbon junctions between graphene electrodes are investigated by means of first-principles quantum transport calculations. First the dependence of the transmission function on the size of the nanoribbon has been studied. Two regimes are highlighted: for small applied bias transport takes place via tunneling and the length of the ribbon is the key parameter that determines the junction conductance; at higher applied bias resonant transport through HOMO and LUMO starts to play a more determinant role, and the transport properties depend on the details of the geometry (width and length) of the carbon nanoribbon. In the case of the thinnest ribbon it has been verified that a tilted geometry of the central phenyl ring is the most stable configuration. As a consequence of this rotation the conductance decreases due to the misalignment of the $pi$ orbitals between the phenyl ring and the remaining part of the junction. All the computed transmission functions have shown a negligible dependence on different saturations and reconstructions of the edges of the graphene leads, suggesting a general validity of the reported results

Early Life Conditions and Financial Risk–Taking in Older Age

Using life-history survey data from eleven European countries, we investigate whether childhood conditions, such as socioeconomic status, cognitive abilities and health problems influence portfolio choice and risk attitudes later in life. After controlling for the corresponding conditions in adulthood, we find that superior cognitive skills in childhood (especially mathematical abilities) are positively associated with stock and mutual fund ownership. Childhood socioeconomic status, as indicated by the number of rooms and by having at least some books in the house during childhood, is also positively associated with the ownership of stocks, mutual funds and individual retirement accounts, as well as with the willingness to take financial risks. On the other hand, less risky assets like bonds are not affected by early childhood conditions. We find only weak effects of childhood health problems on portfolio choice in adulthood. Finally, favorable childhood conditions affect the transition in and out of risky asset ownership, both by making divesting less likely and by facilitating investing (i.e., transitioning from non-ownership to ownership).Portfolio Choice, Childhood Socio-economic Status, Cognition, Health, Financial Risk

Calda bordalesa: utilidades e preparo.

bitstream/item/38833/1/FOL200837.pd

Segurança alimentar e horticultura agroecológica familiar.

bitstream/item/50007/1/12.pdfSIDE 12/09 - Dourados Informa, 07 jan. 2009; SIDE 12/09B - Infobibos, 2009; SIDE 12/09C - Agora MS, 7 jan. 2009; SIDE 012/09D - Hoje MS , 07 jan. 2009

VIRTUAL MEMORIES: ARCHIVAL KNITWEAR THROUGH 3D MODELLING SOFTWARE AND NEW MEDIA

Background: The need to adapt archival knowledge to new technologies has always been a crucial part of the transmission of said archives (1) furthered in recent years by the digital transition of knowledge and cultural change driven by the industry 4.0 and 5.0 (2). In this framework, knitwear archives have started to digitalize their pieces, but as today there appears to be a lack of development in the virtualization of assets through 3D modelling softwares, under the impression that it is impossible to achieve realistic digital twins of knitwear clothes (3). Trying to develop knitwear archival fashion through the use of 3D modelling techniques paves the way for overcoming physical limitations in educational and informative fields, other than being in line with the history of knitwear, which has always been pioneering innovation in the design process. Aim: This research has the aim to investigate on the best method of virtualization of knitwear archival pieces though 3D modelling software, with the aim of using said digital twins for educational and promotional purposes. In order to do so, the research was conducted starting from the knitwear production of Gianfranco Ferre, preserved into Gianfranco Ferre’s Research Centre, exploring the crucial points this production and the main focus to be transmitted through digital technologies. Method: Data about pre-existent 3D fashion modelling software was acquired through first-hand research and the selection of pieces was virtualized combining previously set knowledge and discoveries of new methos of utilization of software, interpreting with analytical critique the results, their possible improvements, and implications for the field. Conclusion: The results of this research show interesting developments for the virtualization of knitwear pieces with educational and promotional purposes, suggesting a method of use of non-specific software and a way to overcome physical limitations in the transmission of archival knowledge. Moreover, it is intended as an inspiration for further software development, in order to facilitate the future seamless virtualization of knitwear

Aurones: Golden resource for active compounds

Deemed as poorly represented in nature, aurones have been often overlooked by researchers compared to other members of the flavonoid superfamily. However, over the past two decades, Abstract: Deemed as poorly represented in nature, aurones have been often overlooked by researchers compared to other members of the flavonoid superfamily. However, over the past two decades, they they have been reassessed by the scientific community, who are increasingly appreciating their ability to modulate several biological pathways. This review summarizes the recent literature on this have been reassessed by the scientific community, who are increasingly appreciating their ability to modulate several biological pathways. This review summarizes the recent literature on this class of class of compounds, which has been analyzed from both a chemical and a functional point of view. compounds, which has been analyzed from both a chemical and a functional point of view. Original Original articles, reviews and editorials featured in Pubmed and Scifinder over the last twenty years articles, reviews and editorials featured in Pubmed and Scifinder over the last twenty years have been have been taken into account to provide the readers with a view of the chemical strategies to obtain taken into account to provide the readers with a view of the chemical strategies to obtain them, their them, their functional properties, and their potential of technological use. The resulting comprehensive picture aims at raising the awareness of these natural derivatives as effective drug candidates, functional properties, and their potential of technological use. The resulting comprehensive picture aims at raising the awareness of these natural derivatives as effective drug candidates, fostering the fostering the development of novel synthetic analogues. development of novel synthetic analogues

Curing hemoglobinopathies : challenges and advances of conventional and new gene therapy approaches

Inherited hemoglobin disorders, including beta-thalassemia (BT) and sickle-cell disease (SCD), are the most common monogenic diseases worldwide, with a global carrier frequency of over 5%.1 With migration, they are becoming more common worldwide, making their management and care an increasing concern for health care systems. BT is characterized by an imbalance in the \u3b1/\u3b2-globin chain ratio, ineffective erythropoiesis, chronic hemolytic anemia, and compensatory hemopoietic expansion.1 Globally, there are over 25,000 births each year with transfusion-dependent thalassemia (TDT). The currently available treatment for TDT is lifelong transfusions and iron chelation therapy or allogenic bone marrow transplantation as a curative option. SCD affects 300 million people worldwide2 and severely impacts the quality of life of patients who experience unpredictable, recurrent acute and chronic severe pain, stroke, infections, pulmonary disease, kidney disease, retinopathy, and other complications. While survival has been dramatically extended, quality of life is markedly reduced by disease- and treatment-associated morbidity. The development of safe, tissue-specific and efficient vectors, and efficient gene-editing technologies has led to the development of several gene therapy trials for BT and SCD. However, the complexity of the approach presents its hurdles. Fundamental factors at play include the requirement for myeloablation on a patient with benign disease, the age of the patient, and the consequent bone marrow microenvironment. A successful path from proof-of-concept studies to commercialization must render gene therapy a sustainable and accessible approach for a large number of patients. Furthermore, the cost of these therapies is a considerable challenge for the health care system. While new promising therapeutic options are emerging,3,4 and many others are on the pipeline,5 gene therapy can potentially cure patients. We herein provide an overview of the most recent, likely potentially curative therapies for hemoglobinopathies and a summary of the challenges that these approaches entail