22 research outputs found

    Reframing professional development through understanding authentic professional learning

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    Continuing to learn is universally accepted and expected by professionals and other stakeholders across all professions. However, despite changes in response to research findings about how professionals learn, many professional development practices still focus on delivering content rather than enhancing learning. In exploring reasons for the continuation of didactic practices in professional development, this article critiques the usual conceptualization of professional development through a review of recent literature across professions. An alternative conceptualization is proposed, based on philosophical assumptions congruent with evidence about professional learning from seminal educational research of the past two decades. An argument is presented for a shift in discourse and focus from delivering and evaluating professional development programs to understanding and supporting authentic professional learning

    Immunohistochemical expression of vascular endothelial growth factor and matrix metalloproteinase-9 in radicular and residual radicular cysts

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    OBJECTIVE: This study assessed and compared the immunoexpression of vascular endothelial growth factor (VEGF) and matrix metalloproteinase-9 (MMP-9) in radicular cysts (RCs) and residual radicular cysts (RRCs), relating them to the angiogenic index and the intensity of the inflammatory infiltrate. MATERIAL AND METHODS: Twenty RCs and 10 RRCs were evaluated by immunohistochemistry using anti-VEGF and anti-MMP-9 antibodies. The angiogenic index was determined by microvessel count (MVC) using anti-von Willebrand factor antibody. RESULTS: The expression of both VEGF and MMP-9 was higher in RCs than in RRCs. RCs and RRCs presented strong epithelial expression of VEGF, irrespective of the intensity of the inflammatory infiltrate. Lesions with strong expression of MMP-9 showed significantly higher number of immunopositive cells for VEGF (p<0.05) and higher MVC (p<0.05). Lesions with dense inflammatory infiltrate exhibited significantly higher MVC (p<0.05) and higher number of immunopositive cells for VEGF (p<0.05). There was a positive correlation between both MVC (p<0.05) and the quantity of immunopositive cells for VEGF (p<0.05), with intensity of the inflammatory infiltrate. In addition, it was observed a positive correlation between the number of immunopositive cells for VEGF and MVC (p<0.05). CONCLUSIONS: VEGF and MMP-9 might play important roles in the angiogenesis in RCs and RRCs. In these lesions, the expression of these molecules and the MVC is closely related to the intensity of the inflammatory infiltrate. The expression of VEGF in the epithelial lining of RCs and RRCs might be important for the enlargement of these lesions

    Spatial pattern, water use and risk levels associated with the transmission of schistosomiasis on the north coast of Pernambuco, Brazil Padrão espacial, uso da água e níveis de risco associados à transmissão da esquistossomose no litoral norte de Pernambuco, Brasil

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    This study aimed to describe epidemiological aspects of schistosomiasis in Carne de Vaca, Goiana, on the coast of Pernambuco State, Brazil and analyze the spatial distribution of households' sanitary conditions and patterns of water contact. A parasitological survey was conducted between 2006 and 2007. An indicator was set to establish risk levels for schistosomiasis based on variables of water contact pattern, household characteristics and proximity to the foci of vector snails. The prevalence was 18.71 in men and 15.96 in women. The age groups most affected were 20-29 years among men and 10-19 among women. The most common parasite load was 1-99 eggs per gram of feces. The prevalence was 17.3 cases per 100 inhabitants and its spatial distribution was not homogeneous. The Bayesian analysis proved unsatisfactory. It is concluded that schistosomiasis is endemic in Carne de Vaca and the risk indicator, based on geoprocessing, proved to be satisfactory, highlighting areas where the problem is more acute.<br>O estudo objetivou descrever aspectos epidemiológicos da esquistossomose em Carne de Vaca, litoral de Pernambuco, Brasil, e analisar a distribuição espacial das condições de esgotamento sanitário e padrão de contato com a água. Foi realizado um inquérito parasitológico entre 2006 e 2007, e criado indicador de risco para a esquistossomose com base em variáveis do padrão de água de contato, características do agregado familiar e da proximidade com focos de moluscos vetores. A prevalência em homens foi de 18,71, e 15,96 em mulheres. A faixa etária mais acometida em homens e mulheres foi de 20-29 e 10-19, respectivamente. A carga parasitária mais freqüente foi de 1-99 ovos por grama de fezes. A prevalência foi de 17,3 casos por 100 habitantes e sua distribuição espacial não foi homogênea. A estatística Bayesiana não se mostrou satisfatória. Conclui-se que a esquistossomose é endêmica em Carne de Vaca e que o indicador de risco com base em geoprocessamento revelou-se satisfatório, destacando as áreas onde o problema é mais relevante
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