84 research outputs found
A Case of a Giant Congenital Melanocytic Nevus Treated by Curettage with the Application of Cultured Epidermal Autografts before 6 Months of Age
Curettage is common in the treatment of a giant congenital melanocytic nevus (GCMN) in infants and should generally be performed before 6 months of age. Post-curettage retarded epithelialization often interferes with the ability to perform multiple operations within a short interval, and thus, it is difficult to treat large lesions in the neonatal period. We herein report a case of a GCMN comprising 20% of the total body surface area, which required multi-stage curettage, in which a cultured epithelial autograft was used to promote epithelialization of the post-curettage wound. The patient was a 1-month-old boy with a GCMN in his head, neck, chest, back, buttock, left upper arm, and a few satellite lesions. A four-stage operation was performed between 3 and 6 months of age; the cultured epithelial autograft took well after each operation, and complete epithelialization was observed at postoperative days 20, 23, 27, and 12, respectively. Seven months after the last surgery, hypertrophic scar formation was only observed in a small area of the left upper arm without axillary contracture. The color of the treated area improved, except for slight partial re-pigmentation. A skin biopsy was obtained from the re-pigmented area. The results demonstrated that nevus cells remained in the basal layer of the epidermis, hair follicles, and deep layer of the remaining dermis, suggesting that the recurrent nevus cells in the regenerated epidermis migrated from hair follicles. We conclude that the combination of curettage and the application of a cultured epithelial autograft is a promising option for GCMN treatment
Squamous Cell Carcinoma of the Scalp after Artificial Hair Implantation
A 48-year-old man with a protruding tumor on the parietal region had undergone treatment of alopecia using artificial synthetic fibers 2 or 3 times a year for 10 years from 30 to 39 years old. Three months before the first consultation at our hospital, he noticed a small tumor that had gradually shown bleeding and discharge, with expansion of the affected area. A diagnosis of squamous cell carcinoma (SCC) was made based on a biopsy, and we resected the tumor with a 1-cm surgical margin from the reddened area around the protruding tumor (14 × 11 cm), including the periosteum membrane. No tight adhesion was found between the periosteum and skull, so we excised the outer table of the skull of the central part (diameter: 8 cm) for a pathological analysis. A pathological study showed moderately differentiated SCC with a negative surgical margin. The whole tumor was surrounded by scar tissue with buried artificial hair implants. The second surgery was performed on the 15th postoperative day. An anterolateral thigh flap was divided into 2 flaps to fit the circle-shaped wound. This is the second report of SCC developing after artificial hair implantation in the frontal-parietal scalp. The whole protruding tumor was surrounded by scar tissue with buried artificial hair implants. Proving the direct causal relationship between inflammation of scar tissue and SCC generation is difficult; however, our pathological findings support the possibility of the harmful effects of artificial hair implants
A Novel Real-time Navigation System for Lymphaticovenular Anastomosis Using Projection Mapping with Indocyanine Green Fluorescence
Impact of Ambulation Status in Patients with End-stage Renal Disease on Hemodialysis due to Diabetic Nephropathy : The PREDICT Study
Article信州医学雑誌 68(3): 131-138(2020)journal articl
Measurement of low-energy antiproton detection efficiency in BESS below 1 GeV
An accelerator experiment was performed using a low-energy antiproton beam to
measure antiproton detection efficiency of BESS, a balloon-borne spectrometer
with a superconducting solenoid. Measured efficiencies showed good agreement
with calculated ones derived from the BESS Monte Carlo simulation based on
GEANT/GHEISHA. With detailed verification of the BESS simulation, the relative
systematic error of detection efficiency derived from the BESS simulation has
been determined to be 5%, compared with the previous estimation of
15% which was the dominant uncertainty for measurements of cosmic-ray
antiproton flux.Comment: 13 pages, 7 figure
Precise Measurement of Cosmic-Ray Proton and Helium Spectra with the BESS Spectrometer
We report cosmic-ray proton and helium spectra in energy ranges of 1 to 120
GeV and 1 to 54 GeV/nucleon, respectively, measured by a balloon flight of the
BESS spectrometer in 1998. The magnetic-rigidity of the cosmic-rays was
reliably determined by highly precise measurement of the circular track in a
uniform solenoidal magnetic field of 1 Tesla. Those spectra were determined
within overall uncertainties of +-5 % for protons and +- 10 % for helium nuclei
including statistical and systematic errors.Comment: 12 pages, 4 figure
Measurements of atmospheric muon spectra at mountain altitude
We report new measurements of the atmospheric muons at mountain altitude. The
measurement was carried out with the BESS detector at the top of Mt. Norikura,
Japan. The altitude is 2,770 m above sea level. Comparing our results and
predictions given by some interaction models, a further appropriate model has
been investigated. These studies would improve accuracy of atmospheric neutrino
calculations.Comment: Mean momentum in Table 1 was correcte
Measurements of Cosmic-ray Low-energy Antiproton and Proton Spectra in a Transient Period of the Solar Field Reversal
The energy spectra of cosmic-ray low-energy antiprotons and protons have been
measured by BESS in 1999 and 2000, during a period covering the solar magnetic
field reversal. Based on these measurements, a sudden increase of the
antiproton to proton flux ratio following the solar magnetic field reversal was
observed, and it generally agrees with a drift model of the solar modulation.Comment: 4 pages, 4 figures, revised version accepted for publication in Phys.
Rev. Let
Influence of γ/γ’ Composite Microstructure on Crack Tip Deformation Behavior in Ni-Based Single Crystal Superalloy
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