Oral health related quality of life among adults reffered to dental clinic of Babol Faculty of Dentistry in 2009-2011

Introduction: The quality of life is defined as the individual's sense of well-being and their satisfaction with daily work as influenced by dental and oral conditions. Oral diseases are very common and have impacts on the different aspects of individual's life and can change their social performances roles, in other words, they can change the quality of life. The aim of this study was to evaluae the impact of oral problems on quality of life in adults who referred to Babol Faculty of Dentistry during 2009-2011. Methods: This cross-sectional study was performed using a non-randomized sampling method. In this study, 500 patients who referred to Babol Faculty of Dentistry age 20-50 years were selected. Then all the questions in OIDP (Oral Impact on Daily Performance) questionnaire which were translated into persian from english were asked and completed. These questions are valuable and reliable for Iranians based on the previous studies. Finally, the data were analyzed by SPSS statistical software. Results: According to this study, oral problems have effected on (80.6%) of the patients’ quality of life. Gender, occupation, level of education and general health have impacted on OIDP score changes. There were significant differences in gender, occupation and level of education. In this study, the general and oral health conditions scores showed a significant association with OIDP score. Most of the patients’ complaint was about eating (64.4%), but going outside and shopping were the least (10%). Conclusions: According to the results of this study, tooth pain was the most oral and dental problem and tooth shape and size were the least effective on the oral health related quality of life. This shows that the most needed treatment are tooth restoration، root canal therapy and surgical treatment for pain relief

Coronally advanced flap and connective tissue graft with or without plasma rich in growth factors (PRGF) in treatment of gingival recession

Several researchers have tried to improve the results of gingival recession treatment techniques. One of the methods is to use growth factors The present study was undertaken to evaluate the effect of CAF (coronally advanced flap) + CTG (connective tissue graft) + PRGF (plasma rich in growth factors) in the treatment of Miller Class I buccal gingival recession. Twenty-two teeth with Miller Class I gingival recession in 6 patients 26 ? 47 years of age were included in a split-mouth designed randomized controlled trial (RCT). In each patient, one side was treated with CAF + CTG + PRGF (test) and the other side was treated with CAF + CTG (control). The following parameters were measured before surgery and up to 6 months after surgery on the mid-buccal surface of the tooth: keratinized tissue width (KTW), clinical attachment level (CAL), probing depth (PD), vertical recession depth (VRD), recession depth (RD), gingival thickness (GT), root coverage in percentage (RC%) and the distance between the CEJ and mucogingival junction (MGJL). Data were analyzed with paired t-test and repeated measures ANOVA. After 6 months noticeable improvements were observed in both groups in all the variables measured except for PD; however, the differences between the two groups were not significant. RC% was 80 ± 25% and 67 ± 28% in the test and control groups, respectively, after 6 months. Both CAF + CTG + PRGF and CAF + CTG treatment modalities resulted in favorable root coverage; however, the addition of PRGF added no measurable significant effect

A case report of neurofibromatosis

Introduction: Neurofibromatosis is a genetic disease characterized by multifocal benign tumors of peripheral nerves, called neurofibromas, and pigmented spots on the skin which inherited as autosomal-dominant. The most common form of the disease is neurofibromatosis type 1, also known as von Recklinghausen's disease of the skin. When an individual has small number of lesions in a limited region of the his body, it could be missed by the patient or not acknowledged by the clinicians as a form of neurofibromatosis. We present here, a case of an 18-year-old male with neurofibromatosis type 1who referred to Babol Dental School for a routine dental examination

Reliability and validity of the persian version of the General Oral Health Assessment Index (GOHAI)

Introduction: As the oral health related quality of life has been important in many dental patients GOHAI is an acceptable tool, preparing its Persian version can be useful in oral health research among Persian populations. The aim of this study was to evaluate the reliability and validity of the Persian version of General Oral Health Assessment Index (GOHAI). Methods: Translation was performed using the forward-backward process. The final Persian version was then tested through an interview and test-retest to evaluate its comprehensibility and reliability. A sample of 150 subjects (20-65 years old) was requested to answer the GOHAI items prior to a clinical examination. Data on the subjects’ socio-demographic characteristics and self-rating report of oral health, general health and dental care needs were recorded. Internal consistency was calculated by Cronbach’s α. Interview and test-retest reliability was evaluated by weighted kappa. Concurrent validity was assessed by comparing GOHAI scores and self-rated measures of oral health, general health and perceived dental care needs. Discriminant validity was tested by comparing GOHAI scores with clinical oral condition. Results: The mean GOHAI score was 46.78±7.85. Cronbach’s α (0.78) showed a high internal consistency and homogeneity between items. Weighted kappa coefficient for the interview varied from 0.60 to 0.96 and was between 0.33 and 0.64 for test-retest. Bland-Altman plot displayed a good agreement between the two GOHAI scores for both the interview and test-retest. There was no significant relationship between GOHAI scores and self-rating oral health (p=0.090), but there was a relationship between self-rating general health and mean GOHAI scores (p=0.047). Also, the low GOHAI scores were associated with the perceived dental care needs (p=0.001). There was an opposite correlation between GOHAI scores and caries and missing teeth (p<0.0001). Conclusions: The Persian version of the GOHAI exhibits acceptable reliability and validity, so it can be used widely throughout the Persian communities

Investigating the effect of nifedipine mucosal adhesive on the wound healing process in the palate: A clinical trial study

Introduction: Nifedipine (NF) is a calcium channel blocker that accelerates wound healing and subsequently relieves pain and discomfort. The aim of the present study was to investigate the local effect of this drug on the wound-healing process of the palate. Materials & Methods: In this triple-blind clinical trial study, 31 patients who were referred to the Periodontology Department of Babol Dental School (14 in the experimental group and 17 in the control group) were examined. They were candidates for gingival surgery and needed a palate transplant. Mucotom was used to create identical wounds in the palate (transplant donor). After a free gingival grafting, the active ingredient of 0.3% NF was applied as a mucosal adhesive (made of chitosan) in the area of the graft (palate). Patients were examined and recorded on days 2, 4, 7, 14, and 30 after surgery for wound closure and healing criteria (Landry & Manchester scar scale) and pain (VAS). Sutures were removed on day 7 of the study. Data were analyzed with SPSS 20 and chi-square, Kruskal-Wallis and Mann-Whitney tests. The significance level was set at 0.05. Results: Based on Landry and Manchester criteria, the wound healing process in the two groups was not significant (p=0.125). There was no significant difference between mean wound size reduction and VAS in both treatment and control groups (p=0.253). Conclusion: Topical NF has no effect on the natural process of healing oral mucosal ulcers and reducing pain

Evaluation of Interleukin- 6 Levels in Saliva of patients with Oral Lichen Planus

Introduction: Oral lichen planus (OLP) is a chronic mucocutaneous inflammatory disorder with an unknown etiology. Although a considerable body of evidence suggests that immunologic factors are involved in the etiology of OLP, the involvement of cytokines in the pathogenesis of the disease is not fully understood yet. The aim of the present study was to assess interleukin-6 (IL-6) levels as a proinflammatory cytokine in the saliva of OLP patients compared to healthy controls. Materials & Methods: This case-control study was conducted on 30 OLP patients (12 males and 18 females) and 30 healthy control subjects, selected from individuals who were referred to the Department of Oral and Maxillofacial Diseases in Faculty of Dentistry, Babol University of Medical Sciences. Samples of unstimulated saliva were collected. Salivary IL-6 levels were measured using an ELISA kit and compared between OLP patients and healthy controls. The collected data were analyzed by Chi-square, independent t-test, and receiver operating characteristic (ROC) curve using SPSS 18. Sensitivity, specificity, positive predictive values (PPVs), and negative predictive values (NPVs) ​​were calculated. A value of p<0.05 was considered significant. Results: Mean salivary IL-6 values in OLP patients and healthy controls were 24.68±9.90 ng/L and 13.76±9.27 ng/L, respectively. The difference was statistically significant (P<0.001). The mean IL-6 values in reticular and erosive forms of OLP clinically were 24.35±9.26 ng/L and 24.91±10.64 ng/L, respectively. This difference was not statistically significant (P=0.87). Conclusions: Higher levels of IL-6 in saliva of OLP patients compared with healthy controls support the role of IL-6 in the pathogenesis of the disease

Evaluation of knowledge toward oral cancer and treatment complications among general dentists of babol, iran (2015)

Introduction: Oral cancer is the most common malignancy in head and neck region. Primary diagnosis is critical and low knowledge of dentists can lead to improper or delayed diagnosis. The aim of this study was to evaluate the knowledge of general dentists regarding oral cancer and the complications of its treatment in Babol, Iran. Materials &Methods: This cross-sectional study was performed on all general dentists working in Babol. Seventy-six dentists entered into the study and filled out the questionnaire. Data were analyzed by SPSS software. Results: Mean score of knowledge in the group with more than 21-years-experience was significantly higher than the group with less than 10-years-experience (p=0.017). There was a positive correlation between total knowledge and years of experience (p=0.001). There was no significant relationship between other criteria with total score of knowledge (p.0.05). Conclusion: It seems that knowledge the babol dentists’ regarding oral cancer and cancer treatment complications is not sufficient

Frequency of fruit and vegetable consumption and oral health-related quality of life among the elderly in Amirkola (Babol, Iran)

Introduction: Considering that nutrition plays a prominent role in the health of the elderly, oral health and the associated quality of life are very important for a healthy diet. The aim of this study was to investigate the association between the frequency of fruit and vegetable consumption and oral health-related quality of life (OHRQoL) among the elderly in Amirkola. Materials & Methods: This study was part of the second phase of the Amirkola elderly cohort study conducted on 750 older people who underwent a special oral and dental examination in 2016-2020 using the Oral Health Questionnaire. The frequency of fruit and vegetable consumption was assessed with the Semi-Quantitative Food Frequency Questionnaire (SQFFQ), OHRQoL was assessed with the General Oral Health Assessment Index (GOHAI), and information on age, sex, history of systemic diseases, and the number of teeth was extracted from the full data set completed by specialists for each patient. Data were analyzed with SPSS 20 using the chi-square statistical test, ANOVA, and Pearson correlation coefficient. A value of p<0.05 was considered significant. Results: Non-smokers and people with a higher level of education had a better OHRQoL (P=0.022 and P=0.036, respectively). There was no significant relationship between the frequency of fruit and vegetable consumption and OHRQoL, but a significant relationship was found between the frequency of fresh herb consumption and OHRQoL (p=0.005). In men, there was a significant relationship between the number of teeth and frequency of vegetable consumption as well as between OHRQoL and frequency of fresh herb consumption in men (P=0.048, r=0.096).In women, a significant relationship was observed between the frequency of total vegetable consumption and OHRQoL (p=0.021, r=0.129). Conclusion: According to the results of the present study, it was found that the amount of fruit and vegetable consumption has no effect on improving the OHRQoL among the elderly of Amirkola city

Muco-bioadhesive containing Ginger officinale extract in the management of recurrent aphthous stomatitis a double blind clinical study

Background and objectives: Recurrent aphthous stomatitis (RAS) is the most common oral mucosal lesions in the general population. Various treatment modalities have been used but no specific therapy proved to be definitive. Ginger Officinale (ginger) indicated to have anti-inflammatory properties in herbal medicine. Thus, this study aimed to evaluate the efficacy of Gingerginger containing bioadhesive in treatment of aphthous ulcers. Material and Methods: This was a double-blinded placebo randomized controlled trial. Fifteen patients enrolled in this study. The clinical efficacy of the mucoadhessive on pain, inflammatory zone and ulcer's diameter in the test period was compared with that of the base treatment and no treatment periodss during 10 days of study. Results: Significant reduction in pain as observed on day 5 between placebo (using base bioadhesives) and no-treatment periods at the first phase of the study (4.53 vs. 3.27 p=0.038.( Reduction in inflamed halo diameters was significant on day 1 between no-treatment and ginger containing bioadhesives )46.73 vs 28.67 p=0.044). Other variables such as ulcer's diameter did not indicate any significant differences in both periods. Conclusion: This study indicated that ginger bioadhesive is capable to relieving pain of RAS. However, its efficacy on ulcer diameter, inflamed halo and healing time was not significantly different compared to the results of the placeb received period

Rhabdomyosarcoma of the maxillary gingiva

Rhabdomyosarcoma is a malignant skeletal muscle neoplasm. The tumor is much more common in children, and the most frequent site is head and neck region. Since this tumor is less frequent than other neoplasms in oral cavity, the clinicians sometimes ignore it, working the patients up. Rhabdomyosarcoma is a high-grade malignancy with poor prognosis. Considering the aggressive behavior and various clinical or histopathologic presentations of the tumor, early diagnosis has a significant impact on the treatment outcome and prognosis of the patients. We highlight the importance of combining the clinical, radiographic, and histopathologic examination to obtain a definitive diagnosis in sarcomas of the head and neck region, especially rhabdomyosarcoma. A case of rhabdomyosarcoma of the maxillary gingiva is presented in a 32-year-old woman in which the primary incisional biopsy was erroneously interpreted as an inflammatory process and consequently, the accurate diagnosis postponed for about 10 months