Wild reindeer of the Kamchatka Peninsula - past, present, and future

A unique subspecies of wild reindeer (Rangifer tarandus phylarchus Hollister) that is endemic to the Kamchatka Peninsula has been declining in number since the 1950s due to commercial hunting, increasing industrial development and competition with domestic reindeer. The largest remaining herd of wild reindeer occurs in the Kronotsky Reserve in northeastern Kamchatka, and the reserve is now critical to the preservation of this subspecies of reindeer

Conservation of wild reindeer in Kamchatka

The wild reindeer of Kamchatka were never numerous and probably did not exceed 15 000 in number because of the restricted amount of winter and summer range, and the characteristically deep snow of the peninsula. Before I960, biologists believed there was one population with three major wintering areas. The inaccessibility of the interior of the peninsula provided natural protection for wild reindeer and other wildlife. After I960, the road system was expanded for the benefit of the logging and mining industries, and poorly regulated commercial hunting of wild reindeer expanded. The wild reindeer population declined rapidly, and became fragmented into 3 herds by the early 1970s. The herds in southern and northeastern Kamchatka were reduced to a few hundred animals, but the herd in eastern Kamchatka that was largely protected by the federal Kronotskii Biosphere Reserve recovered. Poorly regulated hunting and competition with domestic reindeer continue to be the major conservation issues facing wild reindeer in Kamchatka

Primary structure of potato Kunitz-type serine proteinase inhibitor

The serine proteinase inhibitor (PSPI-51) isolated from potato tubers (Solanum tuberosum L,) comprises two protein species with pi 5.2 and 6.3, denoted as PSPI-21-5.2 and PSPI-21-6.3, respectively. They were separated by anion exchange chromatography on a Mono Q FPLC column. Both species tightly inhibit human leukocyte elastase, whereas their interaction with trypsin and chymotrypsin is substantially weaker. The sequences of both PSPI-21-5.2 and PSPI-21-6.3 were determined by analysis of overlapping peptides obtained from the oxidized or reduced and S-pyridylethylated proteins after digestion with trypsin or pepsin, Both species of PSPI-21 are composed of two chains, named chains A and B, which are linked by a disulfide bridge between Cys(146) and Cys(157). The other disulfide bridge is located within the A chains between Cys(48) and Cys(97). The amino acid sequences of the large A chains of the two forms, consisting of 150 amino acids residues each, differ in a single residue at position 52. The small chains B, containing 37 and 36 residues in PSPI-21-6.3 and PSPI-21-5.2, respectively, have nine different residues. The entire amino acid sequences of the two inhibitors show a high degree of homology to the other Kunitz-type proteinase inhibitors from plants

Pristupi i rješenja za izradu atlasa u geografskim informacijskim sustavima https://doi.org/10.32909/kg.19.33.1

The features, advantages and disadvantages of using QGIS, ArcGIS and MapInfo Pro when creating atlases of various types (geographic, complex and thematic) are considered in this paper. Schemes for their potential organization are presented and technological schemes for their automated creation in these geographic information systems are proposed. As a result, approaches and solutions for improving geographic information software can be formulated. Algorithms and modules were developed, primarily aimed at formalizing the structure of atlases and automating the design process of their mathematical basis. The development of functionality was implemented using built-in developer tools implemented in MapInfo as the MapBasic language, and in ArcGIS and QGIS in the Python programming language. A summary table was compiled, which presents the basic functionalities required to create atlases in GIS and their implementation in the appropriate software. These proposals will ensure the fulfillment of all requirements necessary for atlas design, primarily at the regional mapping level.U radu se razmatraju obilježja, prednosti i nedostatci softvera QGIS, ArcGIS i MapInfo Pro za izradu različitih tipova atlasa (geografskih, složenih i tematskih). Prikazane su sheme moguće organizacije takvih atlasa te predložene tehnološke sheme za njihovu automatsku izradu u razmatranim geografskim informacijskim sustavima (GIS). Ishod je formulacija pristupa i rješenja za poboljšanje softvera za GIS. Razvijeni su algoritmi i moduli čiji je glavni cilj formaliziranje strukture atlasa i automatizacija procesa oblikovanja njihove matematičke osnove. Razvoj funkcionalnosti ugrađen je s pomoću postojećih alata u softveru MapInfo kao jezik MapBasic, a u softverima ArcGIS i QGIS u jeziku Python. Izrađena je pregledna tablica koja prikazuje osnovne funkcionalnosti potrebne za izradu atlasa u GIS-u te njihovu ugradnju u razmatrani softver. Ti će prijedlozi osigurati ispunjenje svih potrebnih zahtjeva za izradu atlasa, pogotovo na regionalnoj razini kartiranja

STRESS AND ANXIETY AMONG HEALTHCARE WORKERS ASSOCIATED WITH COVID-19 PANDEMIC IN RUSSIA

Background: Mental health of medical workers treating patients with COVID-19 is an issue of increasing concern worldwide. The available data on stress and anxiety symptoms among healthcare workers during the COVID-19 are relatively limited and have not been evaluated in Russia yet. Subjects and methods: The cross-sectional anonymous survey included 1,090 healthcare workers. Stress and anxiety symptoms were assessed using Stress and Anxiety to Viral Epidemics - 9 (SAVE-9) and Generalized Anxiety Disorder - 7 (GAD-7) scales. Logistic regression, Kaiser-Meyer-Olkin two component factor model, Cronbach\u27s alpha and ROC-analysis were performed to determine the influence of different variables, internal structure and consistency, sensitivity and specificity of SAVE-9 compared with GAD-7. Results: The median scores on the GAD-7 and SAVE-9 were 5 and 14, respectively. 535 (49.1%) respondents had moderate and 239 (21.9%) had severe anxiety according to SAVE-9. 134 participants (12.3%) had severe anxiety, 144 (13.2%) had moderate according to GAD-7. The component model revealed two-factor structure of SAVE-9: “anxiety and somatic concern” and “social stress”. Female gender (OR - 0.98, p=0.04) and younger age (OR - 0.65, p=0.04) were associated with higher level of anxiety according to regression model. The total score of SAVE-9 with a high degree of confidence predicted the GAD-7 value in comparative ROC analysis. Conclusions: Healthcare workers in Russia reported high rates of stress and anxiety. The Russian version of the SAVE-9 displayed a good ratio of sensitivity to specificity compared with GAD-7 and can be recommended as a screening instrument for detection of stress and anxiety in healthcare workers

Approaches and Solutions for Creating Atlases in Geographic Information Systems

U radu se razmatraju obilježja, prednosti i nedostatci softvera QGIS, ArcGIS i MapInfo Pro za izradu različitih tipova atlasa (geografskih, složenih i tematskih). Prikazane su sheme moguće organizacije takvih atlasa te predložene tehnološke sheme za njihovu automatsku izradu u razmatranim geografskim informacijskim sustavima (GIS). Ishod je formulacija pristupa i rješenja za poboljšanje softvera za GIS. Razvijeni su algoritmi i moduli čiji je glavni cilj formaliziranje strukture atlasa i automatizacija procesa oblikovanja njihove matematičke osnove. Razvoj funkcionalnosti ugrađen je s pomoću postojećih alata u softveru MapInfo kao jezik MapBasic, a u softverima ArcGIS i QGIS u jeziku Python. Izrađena je pregledna tablica koja prikazuje osnovne funkcionalnosti potrebne za izradu atlasa u GIS-u te njihovu ugradnju u razmatrani softver. Ti će prijedlozi osigurati ispunjenje svih potrebnih zahtjeva za izradu atlasa, pogotovo na regionalnoj razini kartiranja.The features, advantages and disadvantages of using QGIS, ArcGIS and MapInfo Pro when creating atlases of various types (geographic, complex and thematic) are considered in this paper. Schemes for their potential organization are presented and technological schemes for their automated creation in these geographic information systems are proposed. As a result, approaches and solutions for improving geographic information software can be formulated. Algorithms and modules were developed, primarily aimed at formalizing the structure of atlases and automating the design process of their mathematical basis. The development of functionality was implemented using built-in developer tools implemented in MapInfo as the MapBasic language, and in ArcGIS and QGIS in the Python programming language. A summary table was compiled, which presents the basic functionalities required to create atlases in GIS and their implementation in the appropriate software. These proposals will ensure the fulfillment of all requirements necessary for atlas design, primarily at the regional mapping level

The Historical Development of the Law Concerning Demonstrations in Russia

The article is devoted to the of a constitutional right to carry out public events by citizens of Russian Federation. Historical aspect allows us to observe the way constitutional right to carry out public events is regulated and at the same time the scale of democratization of a society. Today we have federal law, which was legislated to define concretely the regulations of the constitution of Russian Federation. And it is a great step for regulating the constitutional right to carry out public events in Russia

Remission in schizophrenia: results of cross-sectional with 6-month follow-up period and 1-year observational therapeutic studies in an outpatient population

<p>Abstract</p> <p>Background</p> <p>A standardized definition of remission criteria in schizophrenia was proposed by the International group of NC Andreasen in 2005 (low symptom threshold for the eight core Positive and Negative Syndrome Scale (PANSS) symptoms for at least 6 consecutive months).</p> <p>Methods</p> <p>A cross-sectional study of remission rate, using a 6-month follow-up to assess symptomatic stability, was conducted in two healthcare districts (first and second) of an outpatient psychiatric service in Moscow. The key inclusion criteria were outpatients with an <it>International Classification of Diseases</it>, 10th edition (ICD-10) diagnosis of schizophrenia or schizoaffective disorder. Remission was assessed using modern criteria (severity and time criteria), PANSS and Global Assessment of Functioning (GAF). Patients who were stable but did not satisfied the symptomatic criteria were included in a further 1-year observational study, with the first group (first district) receiving risperidone (long-acting, injectable) (RLAI) and the second group (second district) continuing to receiving routine treatment. Symptoms were assessed with PANSS, social functioning with the personal and social performance scale, compliance with rating of medication influences scale, and extrapyramidal side effects with the Simpson-Angus scale.</p> <p>Results</p> <p>Only 64 (31.5%) of 203 outpatients met the criteria for symptomatic remission in the cross-sectional study, but at the end of the 6-month follow-up period, 158 (77.8%) were stable (irrespective of remission status). Among these only 53 (26.1%) patients fulfilled the remission criteria. The observational study had 42 stable patients in the RLAI group and 35 in the routine treatment group: 19.0% in the RLAI group and 5.7% in the control group met remission criteria after 12 months of therapy. Furthermore, reduction of PANSS total and subscale scores, as well as improvement in social functioning, was more significant in the first group.</p> <p>Conclusions</p> <p>Only around one-quarter of our outpatient schizophrenic population met full remission criteria. Use of RLAI gave a better remission rate than achieved in standard care with routine treatment. Criteria for remission should take into account clinical course and functioning to support clinical care.</p

Stress, Anxiety, Depression and Burnout in Frontline Healthcare Workers during COVID-19 Pandemic in Russia

During the COVID-19 pandemic, healthcare workers (HCWs) have been subject to increased workload while also exposed to many psychosocial stressors. Most studies reported high levels of depression and anxiety among HCWs worldwide. Our study is based on two online surveys of 2195 HCWs from different regions of Russia during spring and autumn epidemic outbreaks revealed the rates of anxiety, stress, depression, emotional exhaustion and depersonalization and perceived stress as 32.3%, 31.1%, 45.5%, 74.2%, 37.7%,67.8%, respectively. Moreover, 2.4% of HCWs reported suicidal thoughts. Revealed risk factors included: female gender, younger age, working for over 6 months, living outside of Moscow or Saint Petersburg, the fear of getting infected or infecting family and friends. These results demonstrate the need for urgent supportive programs for HCWs fighting COVID-19 that fall into higher risk factors groups

One-loop corrections to the Drell-Yan process in SANC (I). The charged current case

Radiative corrections to the charged current Drell-Yan processes are revisited. Complete one-loop electroweak corrections are calculated within the automatic SANC system. Electroweak scheme dependence and the choice of the factorization scale are discussed. Comparisons with earlier calculations are presented.Comment: extended version submitted to EPJ