298 research outputs found
Bat mitigation measures on roads - a guideline. - SafeBatPaths Technical Report:SafeBatPaths Technical Report.
SafeBatPaths Fumbling in the dark – effectiveness of bat mitigation measures on roads Effectiveness of mitigating measures for bats – a review:Effectiveness of mitigating measures for bats – a review
Transglycosylating β-d-galactosidase and α-l-fucosidase from Paenibacillus sp. 3179 from a hot spring in East Greenland
Flagermus I Næstved Kommune. Undersøgelse af artsdiversiteten af flagermus I særligt udvalgte områder
Biochemical characterization of bovine plasma thrombin-activatable fibrinolysis inhibitor (TAFI)
<p>Abstract</p> <p>Background</p> <p>TAFI is a plasma protein assumed to be an important link between coagulation and fibrinolysis. The three-dimensional crystal structures of authentic mature bovine TAFI (TAFIa) in complex with tick carboxypeptidase inhibitor, authentic full lenght bovine plasma thrombin-activatable fibrinolysis inhibitor (TAFI), and recombinant human TAFI have recently been solved. In light of these recent advances, we have characterized authentic bovine TAFI biochemically and compared it to human TAFI.</p> <p>Results</p> <p>The four N-linked glycosylation sequons within the activation peptide were all occupied in bovine TAFI, similar to human TAFI, while the sequon located within the enzyme moiety of the bovine protein was non-glycosylated. The enzymatic stability and the kinetic constants of TAFIa differed somewhat between the two proteins, as did the isoelectric point of TAFI, but not TAFIa. Equivalent to human TAFI, bovine TAFI was a substrate for transglutaminases and could be proteolytically cleaved by trypsin or thrombin/solulin complex, although small differences in the fragmentation patterns were observed. Furthermore, bovine TAFI exhibited intrinsic activity and TAFIa attenuated tPA-mediated fibrinolysis similar to the human protein.</p> <p>Conclusion</p> <p>The findings presented here suggest that the properties of these two orthologous proteins are similar and that conclusions reached using the bovine TAFI may be extrapolated to the human protein.</p
Competing magnetic fluctuations and orders in a multiorbital model of doped SrCoAs
We revisit the intriguing magnetic behavior of the paradigmatic itinerant
frustrated magnet , which shows strong and competing
magnetic fluctuations yet does not develop long-range magnetic order. By
calculating the static spin susceptibility within a
realistic sixteen orbital Hubbard-Hund model, we determine the leading
instability to be ferromagnetic (FM). We then explore the effect of doping and
calculate the critical Hubbard interaction strength that is required for
the development of magnetic order. We find that decreases under electron
doping and with increasing Hund's coupling , but increases rapidly under
hole doping. This suggests that magnetic order could possibly emerge under
electron doping but not under hole doping, which agrees with experimental
findings. We map out the leading magnetic instability as a function of doping
and Hund's coupling and find several antiferromagnetic phases in addition to
FM. We also quantify the degree of itinerant frustration in the model and
resolve the contributions of different orbitals to the magnetic susceptibility.
Finally, we discuss the dynamic spin susceptibility, , at finite frequencies, where we recover the anisotropy of the peaks
at and observed by inelastic neutron
scattering that is associated with the phenomenon of itinerant magnetic
frustration. By comparing results between theory and experiment, we conclude
that the essential experimental features of doped SrCoAs are well
captured by a Hubbard-Hund multiorbital model if one considers a small shift of
the chemical potential towards hole doping.Comment: 19 pages, 12 figure
Embedding complex hydrology in the climate system - towards fully coupled climate-hydrology models
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