5,081 research outputs found
Till Studies, Shelburne Vermont
Guidebook for field trips in Vermont: 64th annual meeting October 13, 14, 15, 1972 Burlington, Vermont: Trip G-
Accelerator performance analysis of the Fermilab Muon Campus
Fermilab is dedicated to hosting world-class experiments in search of new
physics that will operate in the coming years. The Muon g-2 Experiment is one
such experiment that will determine with unprecedented precision the muon
anomalous magnetic moment, which offers an important test of the Standard
Model. We describe in this study the accelerator facility that will deliver a
muon beam to this experiment. We first present the lattice design that allows
for efficient capture, transport, and delivery of polarized muon beams. We then
numerically examine its performance by simulating pion production in the
target, muon collection by the downstream beam line optics, as well as
transport of muon polarization. We finally establish the conditions required
for the safe removal of unwanted secondary particles that minimizes
contamination of the final beam.Comment: 10 p
The Robertson v. Princeton Case: Too Important to Be Left to the Lawyers
Offers comments from eleven contributors on the Robertson family's donor rights suit against the Woodrow Wilson School of Public and International Affairs for violation of donor intent. Explores its effects on and implications for the nonprofit sector
Discriminating cool-water from warm-water carbonates and their diagenetic environments using element geochemistry: the Oligocene Tikorangi Formation (Taranaki Basin) and the dolomite effect
Fields portrayed within bivariate element plots have been used to distinguish between carbonates formed in warm- (tropical) water and cool- (temperate) water depositional settings. Here, element concentrations (Ca, Mg, Sr, Na, Fe, and Mn) have been determined for the carbonate fraction of bulk samples from the late Oligocene Tikorangi Formation, a subsurface, mixed dolomite-calcite, cool-water limestone sequence in Taranaki Basin, New Zealand. While the occurrence of dolomite is rare in New Zealand Cenozoic carbonates, and in cool-water carbonates more generally, the dolomite in the Tikorangi carbonates is shown to have a dramatic effect on the "traditional" positioning of cool-water limestone fields within bivariate element plots. Rare undolomitised, wholly calcitic carbonate samples in the Tikorangi Formation have the following average composition: Mg 2800 ppm; Ca 319 100 ppm; Na 800 ppm; Fe 6300 ppm; Sr 2400 ppm; and Mn 300 ppm. Tikorangi Formation dolomite-rich samples (>15% dolomite) have average values of: Mg 53 400 ppm; Ca 290 400 ppm; Na 4700 ppm; Fe 28 100 ppm; Sr 5400 ppm; and Mn 500 ppm. Element-element plots for dolomite-bearing samples show elevated Mg, Na, and Sr values compared with most other low-Mg calcite New Zealand Cenozoic limestones. The increased trace element contents are directly attributable to the trace element-enriched nature of the burial-derived dolomites, termed here the "dolomite effect". Fe levels in the Tikorangi Formation carbonates far exceed both modern and ancient cool-water and warm-water analogues, while Sr values are also higher than those in modern Tasmanian cool-water carbonates, and approach modern Bahaman warm-water carbonate values. Trace element data used in conjunction with more traditional petrographic data have aided in the diagenetic interpretation of the carbonate-dominated Tikorangi sequence. The geochemical results have been particularly useful for providing more definitive evidence for deep burial dolomitisation of the deposits under the influence of marine-modified pore fluids
Signature of the Simplicial Supermetric
We investigate the signature of the Lund-Regge metric on spaces of simplicial
three-geometries which are important in some formulations of quantum gravity.
Tetrahedra can be joined together to make a three-dimensional piecewise linear
manifold. A metric on this manifold is specified by assigning a flat metric to
the interior of the tetrahedra and values to their squared edge-lengths. The
subset of the space of squared edge-lengths obeying triangle and analogous
inequalities is simplicial configuration space. We derive the Lund-Regge metric
on simplicial configuration space and show how it provides the shortest
distance between simplicial three-geometries among all choices of gauge inside
the simplices for defining this metric (Regge gauge freedom). We show
analytically that there is always at least one physical timelike direction in
simplicial configuration space and provide a lower bound on the number of
spacelike directions. We show that in the neighborhood of points in this space
corresponding to flat metrics there are spacelike directions corresponding to
gauge freedom in assigning the edge-lengths. We evaluate the signature
numerically for the simplicial configuration spaces based on some simple
triangulations of the three-sphere (S^3) and three-torus (T^3). For the surface
of a four-simplex triangulation of S^3 we find one timelike direction and all
the rest spacelike over all of the simplicial configuration space. For the
triangulation of T^3 around flat space we find degeneracies in the simplicial
supermetric as well as a few gauge modes corresponding to a positive
eigenvalue. Moreover, we have determined that some of the negative eigenvalues
are physical, i.e. the corresponding eigenvectors are not generators of
diffeomorphisms. We compare our results with the known properties of continuum
superspace.Comment: 24 pages, RevTeX, 4 eps Figures. Submitted to Classical Quantum
Gravit
Optical Structure and Proper-Motion Age of the Oxygen-rich Supernova Remnant 1E 0102-7219 in the Small Magellanic Cloud
We present new optical emission-line images of the young SNR 1E 0102-7219
(E0102) in the SMC obtained with the HST Advanced Camera for Surveys (ACS).
E0102 is a member of the oxygen-rich class of SNRs showing strong oxygen, neon
, and other metal-line emissions in its optical and X-ray spectra, and an
absence of H and He. The progenitor of E0102 may have been a Wolf-Rayet star
that underwent considerable mass loss prior to exploding as a Type Ib/c or
IIL/b SN. The ejecta in this SNR are fast-moving (V > 1000 km/s) and emit as
they are compressed and heated in the reverse shock. In 2003, we obtained
optical [O III], H-alpha, and continuum images with the ACS Wide Field Camera.
The [O III] image captures the full velocity range of the ejecta, and shows
considerable high-velocity emission projected in the middle of the SNR that was
Doppler-shifted out of the narrow F502N bandpass of a previous Wide Field and
Planetary Camera 2 image from 1995. Using these two epochs separated by ~8.5
years, we measure the transverse expansion of the ejecta around the outer rim
in this SNR for the first time at visible wavelengths. From proper-motion
measurements of 12 ejecta filaments, we estimate a mean expansion velocity for
the bright ejecta of ~2000 km/s and an inferred kinematic age for the SNR of
\~2050 +/- 600 years. The age we derive from HST data is about twice that
inferred by Hughes et al.(2000) from X-ray data, though our 1-sigma error bars
overlap. Our proper-motion age is consistent with an independent optical
kinematic age derived by Eriksen et al.(2003) using spatially resolved [O III]
radial-velocity data. We derive an expansion center that lies very close to
X-ray and radio hotspots, which could indicate the presence of a compact
remnant (neutron star or black hole).Comment: 28 pages, 8 figures. Accepted to the Astrophysical Journal, to appear
in 20 April 2006 issue. Full resolution figures are posted at:
http://stevenf.asu.edu/figure
Recommended from our members
Development and characterisation of a Dynamic Mass Instrument (DMI) for use in microwave heating experiments
This study describes the development of an instrument known as the Dynamic Mass Instrument (DMI) for use in microwave heating experiments that will allow greater insight in to the efficacy of the technique. A commercially available load cell is used as the main mechanism of mass measurement with a load arm used to provide microwave isolation of the load cell. The DMI is capable of measuring changes in mass with a mass range of 100 g to 200 g with an accuracy of ± 0.1 g in an environment of 250 W, 2.45 GHz microwaves under a working pressure of 3 mbar. A series of calibrations and experiments have been performed to quantify and clarify the behaviour of the instrument in different environments and scenarios and to ensure the DMI meets preset requirements. The DMI will, in future work, be used in In Situ Resource Utilisation (ISRU) experiments to examine in greater detail the efficacy of using microwave heating as a water extraction technique
Clinical and molecular genetic features of pulmonary hypertension in patients with hereditary hemorrhagic telangiectasia
BACKGROUND: Most patients with familial primary pulmonary hypertension have defects in the gene for bone morphogenetic protein receptor II (BMPR2), a member of the transforming growth factor beta (TGF-beta) superfamily of receptors. Because patients with hereditary hemorrhagic telangiectasia may have lung disease that is indistinguishable from primary pulmonary hypertension, we investigated the genetic basis of lung disease in these patients.
METHODS: We evaluated members of five kindreds plus one individual patient with hereditary hemorrhagic telangiectasia and identified 10 cases of pulmonary hypertension. In the two largest families, we used microsatellite markers to test for linkage to genes encoding TGF-beta-receptor proteins, including endoglin and activin-receptor-like kinase 1 (ALK1), and BMPR2. In subjects with hereditary hemorrhagic telangiectasia and pulmonary hypertension, we also scanned ALK1 and BMPR2 for mutations.
RESULTS: We identified suggestive linkage of pulmonary hypertension with hereditary hemorrhagic telangiectasia on chromosome 12q13, a region that includes ALK1. We identified amino acid changes in activin-receptor-like kinase 1 that were inherited in subjects who had a disorder with clinical and histologic features indistinguishable from those of primary pulmonary hypertension. Immunohistochemical analysis in four subjects and one control showed pulmonary vascular endothelial expression of activin-receptor-like kinase 1 in normal and diseased pulmonary arteries.
CONCLUSIONS: Pulmonary hypertension in association with hereditary hemorrhagic telangiectasia can involve mutations in ALK1. These mutations are associated with diverse effects, including the vascular dilatation characteristic of hereditary hemorrhagic telangiectasia and the occlusion of small pulmonary arteries that is typical of primary pulmonary hypertension
Variability between human experts and artificial intelligence in identification of anatomical structures by ultrasound in regional anaesthesia: a framework for evaluation of assistive artificial intelligence
Background: ScanNavTM Anatomy Peripheral Nerve Block (ScanNavâą) is an artificial intelligence (AI)-based device that produces a colour overlay on real-time B-mode ultrasound to highlight key anatomical structures for regional anaesthesia. This study compares consistency of identification of sono-anatomical structures between expert ultrasonographers and ScanNavâą.
Methods: Nineteen experts in ultrasound-guided regional anaesthesia (UGRA) annotated 100 structures in 30 ultrasound videos across six anatomical regions. These annotations were compared with each other to produce a quantitative assessment of the level of agreement amongst human experts. The AI colour overlay was then compared with all expert annotations. Differences in humanâhuman and humanâAI agreement are presented for each structure class (artery, muscle, nerve, fascia/serosal plane) and structure. Clinical context is provided through subjective assessment data from UGRA experts.
Results: For humanâhuman and humanâAI annotations, agreement was highest for arteries (mean Dice score 0.88/0.86), then muscles (0.80/0.77), and lowest for nerves (0.48/0.41). Wide discrepancy exists in consistency for different structures, both with humanâhuman and humanâAI comparisons; highest for sartorius muscle (0.91/0.92) and lowest for the radial nerve (0.21/0.27).
Conclusions: Human experts and the AI system both showed the same pattern of agreement in sono-anatomical structure identification. The clinical significance of the differences presented must be explored; however the perception that human expert opinion is uniform must be challenged. Elements of this assessment framework could be used for other devices to allow consistent evaluations that inform clinical training and practice. Anaesthetists should be actively engaged in the development and adoption of new AI technology
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