709 research outputs found

    Eclampsia

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    The rise and development of apocalyptic literature in Judaism

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    Thesis (M.A.)--Boston University, 1931. This item was digitized by the Internet Archive

    The validity of the Petrine tradition in the light of modern research

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    Thesis (Ph.D.)--Boston UniversityAccording to Papias and other writers of the early Christian Church, the gospel of Mark embodies the reminiscences of the apostle Peter; Mark, the apostle's hearer and "interpreter," has preserved in his gospel the content of the latter's preaching. This "Petrine tradition" is now brought into question by movements which have produced alternative theories concerning the gospel's origin, theories of revision and redaction, theories of sources, theories of interpretation in the gospel, and theories resulting from the use of the formgeschichtliche method. Does the traditional explanation stand or fall before the proposed hypotheses? In order to arrive at a satisfactory verdict, there must be made a thorough and comprehensive examination of all the evidence which has any bearing upon the matter. When the results of the study of the problem's numerous aspects are taken together, the cumulative effect is thoroughly convincing. At no point has the Petrine tradition been disproved. Instead, every consideration produces possibilities and probabilities that are in complete harmony with it. Alternative theories which have been proposed are purely hypothetical. They have no traditional support whatever. Nor do they disprove the Petrine hypothesis. As matters now stand in the field of New Testament research, the Petrine tradition must be accepted as a valid explanation for the origin of Mark's gospel

    Disruption of cortical microtubules by overexpression of green fluorescent protein-tagged α-tubulin 6 causes a marked reduction in cell wall synthesis

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    It has been known that the transverse orientation of cortical microtubules (MTs) along the elongation axis is essential for normal cell morphogenesis, but whether cortical MTs are essential for normal cell wall synthesis is still not clear. In the present study, we have investigated whether cortical MTs affect cell wall synthesis by direct alteration of the cortical MT organization in Arabidopsis thaliana. Disruption of the cortical MT organization by expression of an excess amount of green fluorescent protein-tagged α-tubulin 6 (GFP-TUA6) in transgenic Arabidopsis plants was found to cause a marked reduction in cell wall thickness and a decrease in the cell wall sugars glucose and xylose. Concomitantly, the stem strength of the GFP-TUA6 overexpressors was markedly reduced compared with the wild type. In addition, expression of excess GFP-TUA6 results in an alteration in cell morphogenesis and a severe effect on plant growth and development. Together, these results suggest that the proper organization of cortical MTs is essential for the normal synthesis of plant cell walls. © 2006 Institute of Botany, Chinese Academy of Sciences

    Provisional BioBrick Language (PoBoL)

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    This BioBricks Foundation Request for Comments (BBF RFC) describes a semantic markup language for publishing and sharing information about BioBricks on the World Wide Web. This BBF RFC includes the recommendation for the minimal information expected when creating a Provisional BioBrick Language (PoBoL) description of BioBricks and for the implementation of the language using Web Ontology Language (OWL)

    Effect of fasting on the toxicity and serum concentration of aminopyrine in rats

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    The acute oral toxicity of aminopyrine is considerably greater in the fasted rat than in the fed rat. Acute toxicity by the ip route was comparable in these two groups of animals. Serum aminopyrine concentrations in the fasted rat reached maximum values within 5 min after oral dosing compared with approximately 15 min after dosing in the fed (ad libitum) animals. Maximum serum aminopyrine concentrations in the fasted rats were more than double those of the fed animals, thus accounting for the increased acute toxicity of this compound in fasted animals. These data not only indicate the importance of serum concentrations in toxicity studies, but also emphasize the necessity for consideration of the short-term nutritional status of the animals used in toxicologic investigations.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/32738/1/0000107.pd

    <i>Trypanosoma brucei rhodesiense</i> transmitted by a single tsetse fly bite in vervet monkeys as a model of human African trypanosomiasis

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    Sleeping sickness is caused by a species of trypanosome blood parasite that is transmitted by tsetse flies. To understand better how infection with this parasite leads to disease, we provide here the most detailed description yet of the course of infection and disease onset in vervet monkeys. One infected tsetse fly was allowed to feed on each host individual, and in all cases infections were successful. The characteristics of infection and disease were similar in all hosts, but the rate of progression varied considerably. Parasites were first detected in the blood 4-10 days after infection, showing that migration of parasites from the site of fly bite was very rapid. Anaemia was a key feature of disease, with a reduction in the numbers and average size of red blood cells and associated decline in numbers of platelets and white blood cells. One to six weeks after infection, parasites were observed in the cerebrospinal fluid (CSF), indicating that they had moved from the blood into the brain; this was associated with a white cell infiltration. This study shows that fly-transmitted infection in vervets accurately mimics human disease and provides a robust model to understand better how sleeping sickness develops
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