Large negotiable certificates of deposit

Certificates of deposit ; Money market

Thomas Mann and Teachers

Thomas Mann\u27s attitude toward the teaching profession is in many ways a negative one. He attacked and ridiculed conventional teachers, and he made teachers of manners laughable and pitiful. Nevertheless, he did have great respect for the good teacher who is a master in his field and who attracts pupils of ability. The pedagogical ideal which Mann developed is a personal, aesthetic one in which teacher and pupil are drawn together by love and where education takes place as an end in itself. The process is creative, not infrequently involving the demonic. It may lead one into difficulty, but it may also be the way in which mankind progresses, because the teacher-pupil relationship in its ideal form must not be a simple copying—that is barbarism—but rather a long struggle in which the pupil finally overcomes his teacher and develops his own personality

Issaquah in January

ISSAQUAH IN JANUARY is an original collection of fifty-one poems accompanied by a preface

RELATION BETWEEN WATER PERMEABILITY AND INTEGRITY OF SULFHYDRYL GROUPS IN MALIGNANT AND NORMAL CELLS

When malignant cells, animal and human, were exposed in vitro to solutions of heavy metals or other selected compounds, three types of cell blebs were produced: (1) acentric blebs, arising from one side of the cell, e. g., by chlormerodrin, meralluride sodium, mercuric chloride; (2) symmetrical blebs; which completely enveloped the cell, e. g., by strong silver protein, auric chloride, p-chloromercuribenzoate; (3) scallop blebs, numerous small spherical elevations which completely covered the cell, e.g., by N-ethyl-maleimide, trivalent arsenicals, iodoacetamide. As indicated by vital stains and morphologic appearance, the blebs arose in healthy cells. They also can be made to appear in vivo in ascites tumor cells by intraperitoneal administration of a blebbing agent. All the bleb-producing chemicals have the property of reacting with protein-sulfhydryl groups by alkylation, oxidation or mercaptide formation. The three bleb types have been induced in 8 mouse and 2 rat ascites tumor cells; in 4 human and 1 mouse malignant cell lines; and in 3 normal cell lines grown in tissue culture. In contrast, cells from normal solid tissues of liver, lung, spleen, kidney, testis and brain from mouse, rat and rabbit failed to produce blebs. A possible interpretation for these observations is presented