7,260 research outputs found
Open access series of imaging studies: Longitudinal MRI data in nondemented and demented older adults
The Open Access Series of Imaging Studies (OASIS) is a series of neuroimaging data sets that is publicly available for study and analysis. The present MRI data set consists of a longitudinal collection of 150 subjects aged 60 to 96 all acquired on the same scanner using identical sequences. Each subject was scanned on two or more visits, separated by at least one year for a total of 373 imaging sessions. Subjects were characterized using the Clinical Dementia Rating (CDR) as either nondemented or with very mild to mild Alzheimerâs disease (AD). 72 of the subjects were characterized as nondemented throughout the study. 64 of the included subjects were characterized as demented at the time of their initial visits and remained so for subsequent scans, including 51 individuals with CDR 0.5 similar level of impairment to individuals elsewhere considered to have âmild cognitive impairmentâ. Another 14 subjects were characterized as nondemented at the time of their initial visit (CDR 0) and were subsequently characterized as demented at a later visit (CDR > 0). The subjects were all right-handed and include both men (n=62) and women (n=88). For each scanning session, 3 or 4 individual T1-weighted MRI scans were obtained. Multiple within-session acquisitions provide extremely high contrast-to-noise making the data amenable to a wide range of analytic approaches including automated computational analysis. Automated calculation of whole brain volume is presented to demonstrate use of the data for measuring differences associated with normal aging and AD
Electroconvection in a Suspended Fluid Film: A Linear Stability Analysis
A suspended fluid film with two free surfaces convects when a sufficiently
large voltage is applied across it. We present a linear stability analysis for
this system. The forces driving convection are due to the interaction of the
applied electric field with space charge which develops near the free surfaces.
Our analysis is similar to that for the two-dimensional B\'enard problem, but
with important differences due to coupling between the charge distribution and
the field. We find the neutral stability boundary of a dimensionless control
parameter as a function of the dimensionless wave number .
, which is proportional to the square of the applied voltage, is
analogous to the Rayleigh number. The critical values and
are found from the minimum of the stability boundary, and its
curvature at the minimum gives the correlation length . The
characteristic time scale , which depends on a second dimensionless
parameter , analogous to the Prandtl number, is determined from the
linear growth rate near onset. and are coefficients in the
Ginzburg-Landau amplitude equation which describes the flow pattern near onset
in this system. We compare our results to recent experiments.Comment: 36 pages, 7 included eps figures, submitted to Phys Rev E. For more
info, see http://mobydick.physics.utoronto.ca
A new method for imaging nuclear threats using cosmic ray muons
Muon tomography is a technique that uses cosmic ray muons to generate three
dimensional images of volumes using information contained in the Coulomb
scattering of the muons. Advantages of this technique are the ability of cosmic
rays to penetrate significant overburden and the absence of any additional dose
delivered to subjects under study above the natural cosmic ray flux.
Disadvantages include the relatively long exposure times and poor position
resolution and complex algorithms needed for reconstruction. Here we
demonstrate a new method for obtaining improved position resolution and
statistical precision for objects with spherical symmetry
Natural Wormholes as Gravitational Lenses
Visser has suggested traversable 3-dimensional wormholes that could plausibly
form naturally during Big Bang inflation. A wormhole mouth embedded in high
mass density might accrete mass, giving the other mouth a net *negative* mass
of unusual gravitational properties. The lensing of such a gravitationally
negative anomalous compact halo object (GNACHO) will enhance background stars
with a time profile that is observable and qualitatively different from that
recently observed for massive compact halo objects (MACHOs) of positive mass.
We recommend that MACHO search data be analyzed for GNACHOs.Comment: 4 pages; plus 4 figures; ReV_TeX 3.0; DOE/ER/40537-001/NPL94-07-01
Second to fourth digit ratio (2D:4D) and concentrations of circulating sex hormones in adulthood
<p>Abstract</p> <p>Background</p> <p>The second to fourth digit ratio (2D:4D) is used as a marker of prenatal sex hormone exposure. The objective of this study was to examine whether circulating concentrations of sex hormones and SHBG measured in adulthood was associated with 2D:4D.</p> <p>Methods</p> <p>This analysis was based on a random sample from the Melbourne Collaborative Cohort Study. The sample consisted of of 1036 men and 620 post-menopausal women aged between 39 and 70 at the time of blood draw. Concentrations of circulating sex hormones were measured from plasma collected at baseline (1990-1994), while digit length was measured from hand photocopies taken during a recent follow-up (2003-2009). The outcome measures were circulating concentrations of testosterone, oestradiol, dehydroepiandrosterone sulphate, androstenedione, Sex Hormone Binding Globulin, androstenediol glucoronide for men only and oestrone sulphate for women only. Free testosterone and oestradiol were estimated using standard formulae derived empirically. Predicted geometric mean hormone concentrations (for tertiles of 2D:4D) and conditional correlation coefficients (for continuous 2D:4D) were obtained using mixed effects linear regression models.</p> <p>Results</p> <p>No strong associations were observed between 2D:4D measures and circulating concentrations of hormones for men or women. For males, right 2D:4D was weakly inversely associated with circulating testosterone (predicted geometric mean testosterone was 15.9 and 15.0 nmol/L for the lowest and highest tertiles of male right 2D:4D respectively (<it>P</it>-<it>trend </it>= 0.04). There was a similar weak association between male right 2D:4D and the ratio of testosterone to oestradiol. These associations were not evident in analyses of continuous 2D:4D.</p> <p>Conclusions</p> <p>There were no strong associations between any adult circulating concentration of sex hormone or SHGB and 2D:4D. These results contribute to the growing body of evidence indicating that 2D:4D is unrelated to adult sex hormone concentrations.</p
Increased aerobic capacity reduces susceptibility to acute highâfat dietâinduced weight gain
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/134165/1/oby21564.pdfhttp://deepblue.lib.umich.edu/bitstream/2027.42/134165/2/oby21564_am.pd
Analytic Controllability of Time-Dependent Quantum Control Systems
The question of controllability is investigated for a quantum control system
in which the Hamiltonian operator components carry explicit time dependence
which is not under the control of an external agent. We consider the general
situation in which the state moves in an infinite-dimensional Hilbert space, a
drift term is present, and the operators driving the state evolution may be
unbounded. However, considerations are restricted by the assumption that there
exists an analytic domain, dense in the state space, on which solutions of the
controlled Schrodinger equation may be expressed globally in exponential form.
The issue of controllability then naturally focuses on the ability to steer the
quantum state on a finite-dimensional submanifold of the unit sphere in Hilbert
space -- and thus on analytic controllability. A relatively straightforward
strategy allows the extension of Lie-algebraic conditions for strong analytic
controllability derived earlier for the simpler, time-independent system in
which the drift Hamiltonian and the interaction Hamiltonia have no intrinsic
time dependence. Enlarging the state space by one dimension corresponding to
the time variable, we construct an augmented control system that can be treated
as time-independent. Methods developed by Kunita can then be implemented to
establish controllability conditions for the one-dimension-reduced system
defined by the original time-dependent Schrodinger control problem. The
applicability of the resulting theorem is illustrated with selected examples.Comment: 13 page
Open Access Series of Imaging Studies: Longitudinal MRI Data in Nondemented and Demented Older Adults
The Ursinus Weekly, February 13, 1961
Jun Kawashima to study at U.C. this semester ⢠Cub and Key asks junior men to apply ⢠Dr. G. S. Pancoast seeks State Assembly position ⢠Dr. Miller begins new TV series on WFIL-TV ⢠Mrs. Rice addresses Collegeville club on Swedish decor ⢠IRC Club to participate in Model UN meeting in N.Y. ⢠Art museum presents series of art programs ⢠Pancoast, Sanders appear on radio; Discuss politics ⢠Spring Festival replaces May Day ⢠Mr. H. Lloyd Jones helps plan conference at Lafayette College ⢠Mr. Jordania to play his own piano pieces for French Club ⢠Rev. Mrs. Kriebel will speak at annual Color Day ⢠Lorelei will be held on Feb. 17 ⢠Y to sponsor Ash Wed. candlelight service ⢠Dean Rothenberger talks to Bible class on European tours ⢠Dr. Harold K. Schilling to address Forum at 8 ⢠Ford, Genter to direct annual senior show ⢠Ardith Mumbauer to show her Costa Rican slides on Feb. 20 ⢠Editorial: Policies ⢠Letters to the editor ⢠Chapel commentary ⢠Seven weeks abroad at music festivals ⢠Village of the damned ⢠Consideration of costs ⢠Tribute for Dr. Dooley ⢠Book review: Herman Wouk\u27s This is my God ⢠Snowbound thoughts ⢠On the theory and practice of in-class sleeping ⢠Spanish sketchbook: The marriage situation ⢠Poomer ⢠On the movie scene ⢠Thoughts at Broad and Locust ⢠Meal time mess ⢠Man over beasts ⢠Wrestlers score another victory, defeat E-Town ⢠Lassies topple strong crusaders; Downed by Grads ⢠Varsity five overpower Johns Hopkins, Fords ⢠Greek gleanings ⢠Cindy Benner is R&B contest rep ⢠Dean\u27s listhttps://digitalcommons.ursinus.edu/weekly/1332/thumbnail.jp
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