Recurrent neuroendocrine adenoma of the middle ear: A case report

Les historiens, qui sont rarement des oiseaux de très bon augure pour la vitalité des croyances qu’ils étudient, ont beaucoup écrit, depuis les années 1970, sur le purgatoire, ce troisième « lieu » de l’au-delà catholique, situé entre enfer et paradis. Support d’une dévotion très populaire, il a connu en Europe trois pics successifs de popularité, à la fin du Moyen Âge, au xviie et au xixe siècles. Le dogme et la croyance ont ainsi puissamment structuré dans la longue durée le rapport aux morts dans les sociétés de culture catholique, en leur conférant une « utilité » particulière, à la fois matérielle, institutionnelle, pastorale et anthropologique, que cet article s’efforce d’explorer.Historians are people who rarely contribute to the continued vitality of the beliefs they study. Since the 1970’s they have written a lot about purgatory, the third place in the catholic beyond. This is situated in between hell and paradise. The belief was the basis of a very popular cult which peaked in popularity in three different periods, one at the end of the Middle Ages, another in the seventeenth and a third in the nineteenth century. The dogma and the belief in purgatory have thus for long periods powerfully structured the relation to the dead in catholic cultures and have given these a particular “usefulness” whether this concerns material, institutional, pastoral or anthropological aspects. The paper attempts to explore these issues

La démodécie chez les Bovins de l’Ouest Africain

Mornet Paul, Mahou R. La démodécie chez les Bovins de l’Ouest Africain. In: Bulletin de l'Académie Vétérinaire de France tome 102 n°1, 1949. pp. 87-92

Prophylaxie de la peste bovine : nouvelle méthode économique de préparation du virus-vaccin bovipestique caprinisé sur boeuf réagissant

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Considérations sur le poids et l'âge des zébus de boucherie du Soudan et de la Haute-Volta (A.O.F.)

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Mild forms of hypophosphatasia mostly result from dominant negative effect of severe alleles or from compound heterozygosity for severe and moderate alleles

<p>Abstract</p> <p>Background</p> <p>Mild hypophosphatasia (HPP) phenotype may result from <it>ALPL </it>gene mutations exhibiting residual alkaline phosphatase activity or from severe heterozygous mutations exhibiting a dominant negative effect. In order to determine the cause of our failure to detect a second mutation by sequencing in patients with mild HPP and carrying on a single heterozygous mutation, we tested the possible dominant effect of 35 mutations carried by these patients.</p> <p>Methods</p> <p>We tested the mutations by site-directed mutagenesis. We also genotyped 8 exonic and intronic <it>ALPL </it>gene polymorphisms in the patients and in a control group in order to detect the possible existence of a recurrent intronic mild mutation.</p> <p>Results</p> <p>We found that most of the tested mutations exhibit a dominant negative effect that may account for the mild HPP phenotype, and that for at least some of the patients, a second mutation in linkage disequilibrium with a particular haplotype could not be ruled out.</p> <p>Conclusion</p> <p>Mild HPP results in part from compound heterozygosity for severe and moderate mutations, but also in a large part from heterozygous mutations with a dominant negative effect.</p

Hypophosphatasia

Hypophosphatasia is a rare inherited disorder characterized by defective bone and teeth mineralization, and deficiency of serum and bone alkaline phosphatase activity. The prevalence of severe forms of the disease has been estimated at 1/100 000