A survey of drench resistance in sheep worms

Sheep worms which are resistant to chemical drenches have been detected with increasing freuency is Western Australia\u27s south-western farming areas between 977 and 1980. These worms have anthelmintic resistance and such genetis resistance puts essential internal parasite control practices at risk. This prompted veterinarians in the Esperance, Albany, Bunbury, Geraldton and Northam areas to survey farms to determine the prevalence of resistance to drenches and to define those sheep management practices which encourage its development. This article describes the survey which was conducted to assess the extent of drench resistance, what causes its build-up and how it can be controlled by using a combination of drenching programme changes and sheep management practices. It has been estimated that drench resistance alone could cost the State\u27s sheep industry $4 million to$6 million a year in lost production, and, as shis survey shows, there is potential for far greater costs if resistance continues to increase

De Novo

The crystal structure of form 4 of the drug 4-[4-(2-adamantylcarbamoyl)-5-tert-butyl-pyrazol-1-yl]benzoic acid is determined using a protocol for NMR powder crystallography at natural isotopic abundance combining solid-state 1H NMR spectroscopy, crystal structure prediction, and density functional theory chemical shift calculations. This is the first example of NMR crystal structure determination for a molecular compound of previously unknown structure, and at 422 g/mol this is the largest compound to which this method has been applied so far

The sandplain lupin : its nutritional value and grazing management

The sandplain lupin or Western Australian blue lupin (Lupinus cosentinii) was introduced to the West Midlands at the turn of the last century. Since that time it has been used as a self-regenerating summer forage for sheep and cattle. Being deep rooted, it has adapted well to the sandy soils from Perth to Northampton, and plantings now cover more than 100,000 ha. As few other improved pasture species will persist on these deep sands the sandplain lupin provides an important source of summer feed for grazing livestock. A stand can be grazed throughout summer at stocking rates of 10 to 15 sheep/ha as long as lupinosis is avoided by correct management. The cultivation of the sandplain lupin as a cash crop is restricted by its high alkaloid level in the seeds and shattering pods