Détermination de l’activité « in vitro » de certains antiseptiques sur le virus de la Rhino-pneumonie du Cheval

Sept antiseptiques ont été éprouvés quant à leur pouvoir viruli cide, à différentes concentrations, sur le virus de la rhino-pneumonie. Ce pouvoir a été apprécié par inoculation au hamster de 4-5 semaines de virus Kentucky Ky-B mis en suspension dans les solutions antiseptiques. Les plus actives sont le teepol, le crésyl et la chloramine T (limite de concentration efficace 1 à 2 p. 1.000). Il y a lieu de tenir compte de ces indications pour le choix des solutions désinfectantes à appliquer sur les animaux ou sur les objets et parois des locaux infectés ou suspects

Proposition de mesures prophylactiques contre l’avortement de la jument par le virus de la rhino-pneumonie

Brion Abel, Fontaine M., Moraillon Robert. Proposition de mesures prophylactiques contre l’avortement de la Jument par le virus de la rhino-pneumonie. In: Bulletin de l'Académie Vétérinaire de France tome 120 n°2, 1967. pp. 89-93

L’exploration fonctionnelle hépatique chez le Chien par l’épreuve à la B. S. P.

Moraillon Robert, Joncourt A., Lafage P. L’exploration fonctionnelle hépatique chez le Chien par l’épreuve à la B. S. P.. In: Bulletin de l'Académie Vétérinaire de France tome 124 n°4, 1971. pp. 203-214

Particules d’aspect viral dans les cellules du lymphosarcome du chien

Dans le tissu ganglionnaire de deux chiens atteints de lymphosarcome, il a été trouvé des particules rappelant les virus des leucémies murines

Grippe équine. — Caractérisation de virus grippaux isolés en 1965

Brion Abel, Cateigne Geneviève, Fontaine M., Fontaine M. P., Moraillon Robert. Grippe équine.— Caractérisation de virus grippaux isolés en 1965. In: Bulletin de l'Académie Vétérinaire de France tome 119 n°5, 1966. pp. 155-163

Peptide immobilisation on porous silicon surface for metal ions detection

In this work, a Glycyl-Histidyl-Glycyl-Histidine (GlyHisGlyHis) peptide is covalently anchored to the porous silicon PSi surface using a multi-step reaction scheme compatible with the mild conditions required for preserving the probe activity. In a first step, alkene precursors are grafted onto the hydrogenated PSi surface using the hydrosilylation route, allowing for the formation of a carboxyl-terminated monolayer which is activated by reaction with N-hydroxysuccinimide in the presence of a peptide-coupling carbodiimide N-ethyl-N'-(3-dimethylaminopropyl)-carbodiimide and subsequently reacted with the amino linker of the peptide to form a covalent amide bond. Infrared spectroscopy (FT-IR) and X-ray photoelectron spectroscopy are used to investigate the different steps of functionalization

Travelers With Cutaneous Leishmaniasis Cured Without Systemic Therapy

Guidelines recommend wound care and/or local therapy as first-line treatment for cutaneous leishmaniasis. An analysis of a referral treatment program in 135 travelers showed that this approach was feasible in 62% of patients, with positive outcome in 83% of evaluable patient

Pimobendan and Mitral Regurgitation 43 Increased Mitral Valve Regurgitation and Myocardial Hypertrophy in Two Dogs With Long-Term Pimobendan Therapy

Abstract The aim of this article is to describe original adverse effects in two dogs chronically treated with the inodilator pimobendan. We report a German shepherd (i.e., dog 1) and a poodle (i.e., dog 2) that were referred to our cardiology unit after receiving pimobendan for 10 and 5 mo, respectively. In both dogs, conventional echo-Doppler examination demonstrated mitral valve regurgitation and myocardial hypertrophy. Tissue Doppler imaging (TDI) was performed in the first case and revealed an abnormal relaxation phase. After the first examination, pimobendan administration was stopped in both cases and dogs were re-examined 3 and 1 mo later, respectively. Mitral valve regurgitation assessed by echocardiography decreased in both dogs, and the systolic heart murmur disappeared in dog 1. Importantly, most echocardiographic and TDI parameters tended to normalize in dog 1, suggesting, at least partial reversal of both myocardial hypertrophy and relaxation abnormality produced during inodilator therapy. This is the first report to describe an increase in mitral regurgitation under clinical conditions in dogs treated with pimobendan. We also suggest that pimobendan may induce ventricular hypertrophy. However, prospective studies are needed to confirm this observation