Leading Groups To Create Healthy Culture Through Accomplishing Tasks Aligned To Strategy

This study examined the link between the consistency of self-evaluation versus peer-evaluation of managers’ skills and the level of relational stress in an organization and was based on two models: (a) the Competing Values Framework (CVF), which measures different management skills of individuals in an organization, and (b) the Healthy versus Toxic Organization Model, which focuses on the stress level in partnerships.  The researchers hypothesized that the lower the stress in the organization, the more consistent the results will be between self-evaluation and peer-evaluation. In an empirical analysis, the researchers found that the relationship was most visible in the area of managers’ facilitator skills. With strong facilitator skills, managers can lead their organizations effectively and stay focused on maintaining strategic alignment. The study also examined how management skills could be most effective in developing a healthy work culture

Fresh shallow valleys in the Martian midlatitudes as features formed by meltwater flow beneath ice

Significant numbers of valleys have been identified in the Martian midlatitudes (30–60°N/S), spatially associated with extant or recent ice accumulations. Many of these valleys date to the Amazonian, but their formation during these cold, dry epochs is problematic. In this study, we look in detail at the form, distribution, and quantitative geomorphology of two suites of these valleys and their associated landforms in order to better constrain the processes of their formation. Since the valleys themselves are so young and thus well preserved, uniquely, we can constrain valley widths and courses and link these to the topography from the Mars Orbiter Laser Altimeter and High-Resolution Stereo Camera data. We show that the valleys are both qualitatively and quantitatively very similar, despite their being >5000 km apart in different hemispheres and around 7 km apart in elevation. Buffered crater counting indicates that the ages of these networks are statistically identical, probably forming during the Late Amazonian, ~100 Ma. In both localities, at least tens of valleys cross local drainage divides, apparently flowing uphill. We interpret these uphill reaches to be characteristic of flow occurring beneath a now absent, relatively thin (order 101–102 m), regionally extensive ice cover. Ridges and mounds occasionally found at the foot of these valley systems are analogous to eskers and aufeis-like refreezing features. On the basis of their interaction with these aufeis-like mounds, we suggest that this suite of landforms may have formed in a single, short episode (perhaps order of days), probably forced by global climate change

Equivariant volumes of non-compact quotients and instanton counting

Motivated by Nekrasov's instanton counting, we discuss a method for calculating equivariant volumes of non-compact quotients in symplectic and hyper-K\"ahler geometry by means of the Jeffrey-Kirwan residue-formula of non-abelian localization. In order to overcome the non-compactness, we use varying symplectic cuts to reduce the problem to a compact setting, and study what happens in the limit that recovers the original problem. We implement this method for the ADHM construction of the moduli spaces of framed Yang-Mills instantons on $\R^{4}$ and rederive the formulas for the equivariant volumes obtained earlier by Nekrasov-Shadchin, expressing these volumes as iterated residues of a single rational function.Comment: 34 pages, 2 figures; minor typos corrected, to appear in Comm. Math. Phy

Stone Quarries and Sourcing in the Carolina Slate Belt

Research Report No. 25, Research Laboratories of Archaeology, University of North Carolina at Chapel Hill. Reports in this series discuss the findings of archaeological excavations and research projects undertaken by the RLA between 1984 and present

Factor Structure of the Barriers to Physical Activity Scale for Youth with Visual Impairments

Youth with visual impairments (VI) often experience unique barriers to physical activity (PA) compared to their sighted peers (Armstrong et al., 2018). A psychometrically sound scale for assessing barriers to PA for youth with VI is needed to facilitate research. The purpose of this paper was to confirm the ability of the previously identified three-factor structure of the Physical Activity Barriers Questionnaire for youth with Visual Impairments (PABQ-VI) to produce scores considered to be valid and reliable (Armstrong et al., 2020; Armstrong et al., 2018) that perform equally well across age, VI severity, and gender. Our results supported the three-factor structure and that the PABQ-VI produces scores considered valid and reliable. Mean, variance, and correlation differences were found in personal, social, and environmental barriers for age and VI severity, but not gender. Researchers can use the PABQ-VI to test and evaluate ways to reduce barriers for this population

Effect of active immunization against growth hormone releasing factor on concentrations of somatotropin and insulin-like growth factor I in lactating beef cows

Two experiments were conducted to determine the effects of immunoneutralization of growth hormone-releasing factor [GRF(1–29)-NH2] on concentrations of somatotropin (ST) and insulin-like growth factor I (IGF-I) in lactating beef cows. In Experiment 1, multiparous Hereford cows were immunized against 2 mg GRF(1–29)-(Gly)4-Cys-NH2 conjugated to human serum albumin (GRFi, n=3) or 2 mg human serum albumin (HSAi, n=3) at 52 ± 1 d prior to parturition. Boosters (1 mg) were administered on days 12, 40 and 114 postpartum (pp). Serum samples were collected at 15-min intervals for 5 hr on days 18, 46 and 120 pp, followed by administration (IV) of an opioid agonist (FK33-824; 10 μg/kg) and an antagonist (naloxone; .5 mg/kg) at hours 5 and 7, respectively. A GRF-analog ([desamino-Tyr1, D-Ala2, Ala15] GRF (1–29)-NH2; 3.5 μg/kg) and arginine (.5 g/kg) were administered at hour 10 on days 47 and 121, respectively. Percentage binding of [125I]GRF (1:100 dilution of serum) 28 d after primary immunization was greater in GRFi (14.3 ± 4.9) than in HSAi (.7 ± .3) cows. Binding increased to 29.3 ± 6.5% after first booster in GRFi cows. Episodic release of ST was abolished by immunization against GRF; concentration and frequency of release of ST were lower (P125I]GRF, absence of pulsatile release of ST, low concentrations of ST and IGF-I and failure of ST to increase after IV opioid agonist or arginine

Elevated Pressure Improves the Extraction and Identification of Proteins Recovered from Formalin-Fixed, Paraffin-Embedded Tissue Surrogates

Proteomic studies of formalin-fixed paraffin-embedded (FFPE) tissues are frustrated by the inability to extract proteins from archival tissue in a form suitable for analysis by 2-D gel electrophoresis or mass spectrometry. This inability arises from the difficulty of reversing formaldehyde-induced protein adducts and cross-links within FFPE tissues. We previously reported the use of elevated hydrostatic pressure as a method for efficient protein recovery from a hen egg-white lysozyme tissue surrogate, a model system developed to study formalin fixation and histochemical processing.In this study, we demonstrate the utility of elevated hydrostatic pressure as a method for efficient protein recovery from FFPE mouse liver tissue and a complex multi-protein FFPE tissue surrogate comprised of hen egg-white lysozyme, bovine carbonic anhydrase, bovine ribonuclease A, bovine serum albumin, and equine myoglobin (55∶15∶15∶10∶5 wt%). Mass spectrometry of the FFPE tissue surrogates retrieved under elevated pressure showed that both the low and high-abundance proteins were identified with sequence coverage comparable to that of the surrogate mixture prior to formaldehyde treatment. In contrast, non-pressure-extracted tissue surrogate samples yielded few positive and many false peptide identifications. Studies with soluble formalin-treated bovine ribonuclease A demonstrated that pressure modestly inhibited the rate of reversal (hydrolysis) of formaldehyde-induced protein cross-links. Dynamic light scattering studies suggest that elevated hydrostatic pressure and heat facilitate the recovery of proteins free of formaldehyde adducts and cross-links by promoting protein unfolding and hydration with a concomitant reduction in the average size of the protein aggregates.These studies demonstrate that elevated hydrostatic pressure treatment is a promising approach for improving the recovery of proteins from FFPE tissues in a form suitable for proteomic analysis

Are upright lateral cervical radiographs in the obtunded trauma patient useful? A retrospective study

BACKGROUND: The best method for radiographic "clearance" of the cervical spine in obtunded patients prior to removal of cervical immobilization devices remains debated. Dynamic radiographs or MRI are thought to demonstrate unstable injuries, but can be expensive and cumbersome to obtain. An upright lateral cervical radiograph (ULCR) was performed in selected patients to investigate whether this study could provide this same information, to enable removal of cervical immobilization devices in the multiple trauma patient. METHODS: We retrospectively reviewed our experience with ULCR in 683 blunt trauma victims who presented over a 3-year period, with either a Glasgow Coma Score <13 or who were intubated at the time of presentation. RESULTS: ULCR was performed in 163 patients. Seven patients had studies interpreted to be abnormal, of which six were also abnormal, by either CT or MRI. The seventh patient's only abnormality was soft tissue swelling; MRI was otherwise normal. Six patients had ULCR interpreted as normal, but had abnormalities on either CT or MRI. None of the missed injuries required surgical stabilization, although one had a vertebral artery injury demonstrated on subsequent angiography. ULCR had an apparent sensitivity of 45.5% and specificity of 71.4%. CONCLUSION: ULCR are inferior to both CT and MRI in the detection of cervical injury in patients with normal plain radiographs. We therefore cannot recommend the use of ULCR in the obtunded trauma patient